CA3109553A1 - Rnai agents for inhibiting expression of 17beta-hsd type 13 (hsd17b13), compositions thereof, and methods of use - Google Patents

Rnai agents for inhibiting expression of 17beta-hsd type 13 (hsd17b13), compositions thereof, and methods of use Download PDF

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Publication number
CA3109553A1
CA3109553A1 CA3109553A CA3109553A CA3109553A1 CA 3109553 A1 CA3109553 A1 CA 3109553A1 CA 3109553 A CA3109553 A CA 3109553A CA 3109553 A CA3109553 A CA 3109553A CA 3109553 A1 CA3109553 A1 CA 3109553A1
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Prior art keywords
rnai agent
hsd17b13
nucleotides
seq
sense strand
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CA3109553A
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English (en)
French (fr)
Inventor
Zhen Li
Rui ZHU
Shawn A. Morales
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Arrowhead Pharmaceuticals Inc
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Arrowhead Pharmaceuticals Inc
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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CA3109553A 2018-09-19 2019-09-18 Rnai agents for inhibiting expression of 17beta-hsd type 13 (hsd17b13), compositions thereof, and methods of use Pending CA3109553A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862733320P 2018-09-19 2018-09-19
US62/733,320 2018-09-19
US201862773707P 2018-11-30 2018-11-30
US62/773,707 2018-11-30
US201962890220P 2019-08-22 2019-08-22
US62/890,220 2019-08-22
PCT/US2019/051707 WO2020061177A1 (en) 2018-09-19 2019-09-18 Rnai agents for inhibiting expression of 17beta-hsd type 13- (hsd17b13), compositions thereof, and methods of use

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Publication Number Publication Date
CA3109553A1 true CA3109553A1 (en) 2020-03-26

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CA3109553A Pending CA3109553A1 (en) 2018-09-19 2019-09-18 Rnai agents for inhibiting expression of 17beta-hsd type 13 (hsd17b13), compositions thereof, and methods of use

Country Status (21)

Country Link
US (1) US12534728B2 (https=)
EP (1) EP3852769A4 (https=)
JP (3) JP7488254B2 (https=)
KR (1) KR102769565B1 (https=)
CN (1) CN113164509B (https=)
AU (1) AU2019342117A1 (https=)
BR (1) BR112021005137A2 (https=)
CA (1) CA3109553A1 (https=)
CL (1) CL2021000669A1 (https=)
CO (1) CO2021003446A2 (https=)
CR (1) CR20210186A (https=)
EC (1) ECSP21027262A (https=)
IL (1) IL281597A (https=)
MX (1) MX2021003077A (https=)
MY (1) MY209138A (https=)
PE (1) PE20211212A1 (https=)
PH (1) PH12021550423A1 (https=)
SG (1) SG11202101698WA (https=)
TW (2) TWI870358B (https=)
UY (1) UY38382A (https=)
WO (1) WO2020061177A1 (https=)

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