CA3080484A1 - Nucleo-reticular multi-cell dual-system eye implant - Google Patents
Nucleo-reticular multi-cell dual-system eye implant Download PDFInfo
- Publication number
- CA3080484A1 CA3080484A1 CA3080484A CA3080484A CA3080484A1 CA 3080484 A1 CA3080484 A1 CA 3080484A1 CA 3080484 A CA3080484 A CA 3080484A CA 3080484 A CA3080484 A CA 3080484A CA 3080484 A1 CA3080484 A1 CA 3080484A1
- Authority
- CA
- Canada
- Prior art keywords
- implant
- reticular
- cell
- nucleo
- dual
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007943 implant Substances 0.000 title claims abstract description 154
- 238000000034 method Methods 0.000 claims abstract description 32
- 230000001497 fibrovascular Effects 0.000 claims abstract description 28
- 230000007159 enucleation Effects 0.000 claims abstract description 10
- 238000001125 extrusion Methods 0.000 claims abstract description 10
- 230000005012 migration Effects 0.000 claims abstract description 7
- 238000013508 migration Methods 0.000 claims abstract description 7
- 239000000560 biocompatible material Substances 0.000 claims abstract description 5
- 210000001519 tissue Anatomy 0.000 claims description 21
- 210000003205 muscle Anatomy 0.000 claims description 19
- 230000003387 muscular Effects 0.000 claims description 10
- 230000006870 function Effects 0.000 claims description 9
- 230000017531 blood circulation Effects 0.000 claims description 5
- 229920000642 polymer Polymers 0.000 claims description 3
- 238000005266 casting Methods 0.000 claims description 2
- 230000001413 cellular effect Effects 0.000 claims description 2
- 238000005520 cutting process Methods 0.000 claims description 2
- 230000002262 irrigation Effects 0.000 claims description 2
- 238000003973 irrigation Methods 0.000 claims description 2
- 239000000919 ceramic Substances 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 239000000835 fiber Substances 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 238000000465 moulding Methods 0.000 claims 1
- 230000001706 oxygenating effect Effects 0.000 claims 1
- 238000006213 oxygenation reaction Methods 0.000 claims 1
- 238000003825 pressing Methods 0.000 claims 1
- 238000000859 sublimation Methods 0.000 claims 1
- 230000008022 sublimation Effects 0.000 claims 1
- 235000013311 vegetables Nutrition 0.000 claims 1
- 238000009941 weaving Methods 0.000 claims 1
- 239000000463 material Substances 0.000 abstract description 26
- 238000013461 design Methods 0.000 abstract description 19
- 239000004626 polylactic acid Substances 0.000 abstract description 18
- 229940079593 drug Drugs 0.000 abstract description 15
- 230000004323 axial length Effects 0.000 abstract description 14
- 239000003814 drug Substances 0.000 abstract description 14
- 238000005516 engineering process Methods 0.000 abstract description 9
- 230000005484 gravity Effects 0.000 abstract description 3
- 238000004891 communication Methods 0.000 abstract description 2
- 230000009977 dual effect Effects 0.000 abstract description 2
- 238000000605 extraction Methods 0.000 abstract description 2
- 210000001508 eye Anatomy 0.000 description 56
- 210000004027 cell Anatomy 0.000 description 44
- 230000010354 integration Effects 0.000 description 17
- 238000001356 surgical procedure Methods 0.000 description 13
- 239000007787 solid Substances 0.000 description 12
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 11
- 238000005259 measurement Methods 0.000 description 11
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 11
- 229920000747 poly(lactic acid) Polymers 0.000 description 9
- 210000004279 orbit Anatomy 0.000 description 8
- 238000002604 ultrasonography Methods 0.000 description 8
- 210000005252 bulbus oculi Anatomy 0.000 description 7
- -1 polyethylene Polymers 0.000 description 7
- 230000008569 process Effects 0.000 description 7
- 239000004698 Polyethylene Substances 0.000 description 6
- 229920000573 polyethylene Polymers 0.000 description 6
- 230000008901 benefit Effects 0.000 description 5
- 210000003786 sclera Anatomy 0.000 description 5
- 208000014674 injury Diseases 0.000 description 4
- 230000002784 sclerotic effect Effects 0.000 description 4
- 239000012620 biological material Substances 0.000 description 3
- 210000000988 bone and bone Anatomy 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 230000000399 orthopedic effect Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000008733 trauma Effects 0.000 description 3
- 241000124008 Mammalia Species 0.000 description 2
- 210000003484 anatomy Anatomy 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000009545 invasion Effects 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 229920000139 polyethylene terephthalate Polymers 0.000 description 2
- 239000005020 polyethylene terephthalate Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000011144 upstream manufacturing Methods 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- 239000013585 weight reducing agent Substances 0.000 description 2
- JJTUDXZGHPGLLC-ZXZARUISSA-N (3r,6s)-3,6-dimethyl-1,4-dioxane-2,5-dione Chemical compound C[C@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-ZXZARUISSA-N 0.000 description 1
- 208000009786 Anophthalmos Diseases 0.000 description 1
- 208000003322 Coinfection Diseases 0.000 description 1
- 241000552118 Cubana Species 0.000 description 1
- 241001331845 Equus asinus x caballus Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000000556 agonist Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000003042 antagnostic effect Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000003560 cancer drug Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000005034 decoration Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- LNEPOXFFQSENCJ-UHFFFAOYSA-N haloperidol Chemical compound C1CC(O)(C=2C=CC(Cl)=CC=2)CCN1CCCC(=O)C1=CC=C(F)C=C1 LNEPOXFFQSENCJ-UHFFFAOYSA-N 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 229960000448 lactic acid Drugs 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000008409 marco Nutrition 0.000 description 1
- 244000078446 marco Species 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000001577 neostriatum Anatomy 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 235000020030 perry Nutrition 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000007151 ring opening polymerisation reaction Methods 0.000 description 1
- 230000011664 signaling Effects 0.000 description 1
- 230000000707 stereoselective effect Effects 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 239000003356 suture material Substances 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/141—Artificial eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
- A61F2002/0081—Special surfaces of prostheses, e.g. for improving ingrowth directly machined on the prosthetic surface, e.g. holes, grooves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
- A61F2002/0086—Special surfaces of prostheses, e.g. for improving ingrowth for preferentially controlling or promoting the growth of specific types of cells or tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
- A61F2240/002—Designing or making customized prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
- A61F2240/002—Designing or making customized prostheses
- A61F2240/004—Using a positive or negative model, e.g. moulds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/006—Additional features; Implant or prostheses properties not otherwise provided for modular
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
Landscapes
- Health & Medical Sciences (AREA)
- Transplantation (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MXMX/A/2017/013845 | 2017-10-27 | ||
MX2017013845A MX2017013845A (es) | 2017-10-27 | 2017-10-27 | Implante ocular duosistema multiceldas nucleoreticular. |
PCT/MX2018/000115 WO2019083350A1 (es) | 2017-10-27 | 2018-10-29 | Implante ocular duosistema multiceldas nucleoreticular |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3080484A1 true CA3080484A1 (en) | 2019-05-02 |
Family
ID=62778653
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3080484A Pending CA3080484A1 (en) | 2017-10-27 | 2018-10-29 | Nucleo-reticular multi-cell dual-system eye implant |
Country Status (14)
Country | Link |
---|---|
US (1) | US11654013B2 (de) |
EP (1) | EP3701909A4 (de) |
JP (1) | JP7482781B2 (de) |
KR (1) | KR20200081389A (de) |
CN (1) | CN111417363B (de) |
AU (1) | AU2018355805A1 (de) |
BR (1) | BR112020008294A2 (de) |
CA (1) | CA3080484A1 (de) |
CL (1) | CL2020001117A1 (de) |
CO (1) | CO2020006207A2 (de) |
IL (1) | IL274267B2 (de) |
MX (1) | MX2017013845A (de) |
RU (1) | RU2020115565A (de) |
WO (1) | WO2019083350A1 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3083080B1 (fr) * | 2018-06-29 | 2021-08-27 | France Chirurgie Instr Sas | Implant orbital comportant des fenetres traversantes pour sutures |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2629877A (en) * | 1946-04-27 | 1953-03-03 | American Optical Corp | Artificial eye |
US2570149A (en) * | 1949-11-25 | 1951-10-02 | American Optical Corp | Device for aiding in performing eye surgery |
US2688139A (en) * | 1950-03-09 | 1954-09-07 | American Optical Corp | Anatomical replacement means |
US4731077A (en) | 1987-06-25 | 1988-03-15 | Allen Edwin L | Universal implant for artificial eyes |
US5466258A (en) | 1993-11-12 | 1995-11-14 | Porex Surgical, Inc. | Orbital implant |
US5466259A (en) | 1994-03-07 | 1995-11-14 | Durette; Jean-Francois | Orbital implant and method |
US5584880A (en) * | 1994-04-28 | 1996-12-17 | Martinez; Miguel | Orbital implant |
US5713955A (en) * | 1996-11-08 | 1998-02-03 | Durette; Jean-Francois | Orbital implant |
US6063117A (en) | 1998-01-22 | 2000-05-16 | Perry; Arthur C. | Porous orbital implant structure |
WO2003037155A2 (en) | 2001-10-30 | 2003-05-08 | Csir | Orbital implant |
RU2240092C1 (ru) * | 2003-09-01 | 2004-11-20 | Всероссийский центр глазной и пластической хирургии | Способ коррекции опорно-двигательной культи при анофтальме |
US8118867B2 (en) * | 2003-12-03 | 2012-02-21 | Arthur C. Perry | Orbital implant coating having bulbously raised suture zone |
JP4401412B2 (ja) * | 2004-09-30 | 2010-01-20 | ジャン・フランソワ デュレット,オキュラリスト インク. | 眼のインプラント |
US7988730B2 (en) | 2004-09-30 | 2011-08-02 | Durette Jean-Francois | Quasi-spherical orbital implant |
US20100121439A1 (en) * | 2007-03-21 | 2010-05-13 | Perry Arthur C | Vaulted perforated coating for orbital implants |
EP2173289A4 (de) * | 2007-07-17 | 2010-11-24 | Transcend Medical Inc | Augenimplantat mit hydrogelausdehnungsfähigkeiten |
WO2009093104A2 (en) * | 2008-01-25 | 2009-07-30 | B & T S.R.L | Use of transesterified olive oil in the cosmetic field |
AU2009257506B2 (en) * | 2008-06-10 | 2014-04-17 | Cook Biotech Incorporated | Quilted implantable graft |
ES2640867T3 (es) | 2008-06-25 | 2017-11-07 | Novartis Ag | Implante ocular con capacidad de cambio de forma |
FR2951070B1 (fr) * | 2009-10-08 | 2011-11-11 | Kasios | Bille a enucleation et procede de fabrication d'une telle bille |
US20120129123A1 (en) * | 2010-11-19 | 2012-05-24 | Yin-Chao Yao | Multi-coordinate orthodontic implant positioning device |
US9289300B2 (en) * | 2012-11-10 | 2016-03-22 | La Fuente's Ocular Prosthetics, Llc | La fuente porus implant matrix |
CN104414773B (zh) * | 2013-08-23 | 2017-03-01 | 深圳迈普再生医学科技有限公司 | 防粘连组织修复膜及其制备方法 |
CN103961751B (zh) * | 2014-04-22 | 2019-10-11 | 卢建熙 | 多功能生物陶瓷义眼台、制备工艺及其应用 |
-
2017
- 2017-10-27 MX MX2017013845A patent/MX2017013845A/es unknown
-
2018
- 2018-10-29 EP EP18869860.9A patent/EP3701909A4/de active Pending
- 2018-10-29 US US16/759,723 patent/US11654013B2/en active Active
- 2018-10-29 RU RU2020115565A patent/RU2020115565A/ru unknown
- 2018-10-29 JP JP2020543450A patent/JP7482781B2/ja active Active
- 2018-10-29 WO PCT/MX2018/000115 patent/WO2019083350A1/es unknown
- 2018-10-29 KR KR1020207013237A patent/KR20200081389A/ko not_active Application Discontinuation
- 2018-10-29 CN CN201880077331.1A patent/CN111417363B/zh active Active
- 2018-10-29 BR BR112020008294-5A patent/BR112020008294A2/pt active Search and Examination
- 2018-10-29 CA CA3080484A patent/CA3080484A1/en active Pending
- 2018-10-29 AU AU2018355805A patent/AU2018355805A1/en not_active Abandoned
- 2018-10-29 IL IL274267A patent/IL274267B2/en unknown
-
2020
- 2020-04-27 CL CL2020001117A patent/CL2020001117A1/es unknown
- 2020-05-21 CO CONC2020/0006207A patent/CO2020006207A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
US20210177572A1 (en) | 2021-06-17 |
WO2019083350A4 (es) | 2019-06-20 |
EP3701909A4 (de) | 2021-08-11 |
CN111417363B (zh) | 2024-01-19 |
IL274267B1 (en) | 2024-02-01 |
MX2017013845A (es) | 2018-03-21 |
RU2020115565A3 (de) | 2022-03-23 |
WO2019083350A1 (es) | 2019-05-02 |
CN111417363A (zh) | 2020-07-14 |
CO2020006207A2 (es) | 2020-05-29 |
IL274267A (en) | 2020-06-30 |
IL274267B2 (en) | 2024-06-01 |
BR112020008294A2 (pt) | 2020-10-20 |
JP2021500214A (ja) | 2021-01-07 |
RU2020115565A (ru) | 2021-11-30 |
AU2018355805A1 (en) | 2020-05-28 |
CL2020001117A1 (es) | 2020-08-21 |
JP7482781B2 (ja) | 2024-05-14 |
EP3701909A1 (de) | 2020-09-02 |
KR20200081389A (ko) | 2020-07-07 |
US11654013B2 (en) | 2023-05-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Baino et al. | Orbital implants: State-of-the-art review with emphasis on biomaterials and recent advances | |
Liu et al. | Porous polyethylene implant for cranioplasty and skull base reconstruction | |
US20060282164A1 (en) | Implant shell and filler apparatus | |
Sami et al. | Perspective on orbital enucleation implants | |
KR20060003852A (ko) | 매크로다공성 합성 수지 및 생활성 유리 입자로부터제조된 복합 외과적 이식물 | |
MXPA04009547A (es) | Implante quirugico. | |
Grecchi et al. | Reconstruction of the zygomatic bone with smartbone®: Case report | |
CN110180027A (zh) | 具有改进的操作特征的脱矿质骨基质 | |
ES2955779T3 (es) | Andamios de ingeniería tisular | |
CN112107394A (zh) | 一种用于颌面骨缺损修复的植入体及其制备方法 | |
US11654013B2 (en) | Nucleo-reticular multi-cell dual-system eye implant | |
CN108670507A (zh) | 自适应的椎间融合器 | |
CN210962457U (zh) | 一种用于颌面骨缺损修复的植入体 | |
Dharadhar et al. | Biomaterials and Its Medical Applications | |
RU2375007C1 (ru) | Способ замещения костных дефектов | |
CN209236469U (zh) | 自适应的椎间融合器 | |
Elmazar et al. | The efficacy of Gore-Tex vs. hydroxyapatite and bone graft in reconstruction of orbital floor defects | |
RU159838U1 (ru) | Орбитальный имплантат | |
JPWO2019083350A5 (de) | ||
Zhang et al. | Composite implants in oculoplastic surgery | |
Schellini | Perspectives on the clinical feasibility of techniques used in anophthalmic socket reconstruction | |
Jordan et al. | Controversies in enucleation technique and implant selection: whether to wrap, attach muscles, and peg? | |
CN213552648U (zh) | 一种骨填充块 | |
US20140277514A1 (en) | La fuente porus implant matrix | |
BRPI0906274A2 (pt) | processo de produção, compósitos, sistema e dispositivos médico-veterinários bio-ativos, biointegráveis, condutores, indutores teciduais para fixação, reparo, reconstrução, remodelação, plastias intra, supra teciduais e/ou totais, permanentes, biológica e fisiologicamente biocompatìveis |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |
Effective date: 20231027 |