WO2019083350A4 - Implante ocular duosistema multiceldas nucleoreticular - Google Patents

Implante ocular duosistema multiceldas nucleoreticular Download PDF

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Publication number
WO2019083350A4
WO2019083350A4 PCT/MX2018/000115 MX2018000115W WO2019083350A4 WO 2019083350 A4 WO2019083350 A4 WO 2019083350A4 MX 2018000115 W MX2018000115 W MX 2018000115W WO 2019083350 A4 WO2019083350 A4 WO 2019083350A4
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WO
WIPO (PCT)
Prior art keywords
canceled
nucleoreticular
multicellular
implant
ocular implant
Prior art date
Application number
PCT/MX2018/000115
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English (en)
French (fr)
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WO2019083350A1 (es
Inventor
Aldo FICHTL GARCÍA
Original Assignee
Fichtl Garcia Aldo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to KR1020207013237A priority Critical patent/KR20200081389A/ko
Application filed by Fichtl Garcia Aldo filed Critical Fichtl Garcia Aldo
Priority to BR112020008294-5A priority patent/BR112020008294A2/pt
Priority to RU2020115565A priority patent/RU2020115565A/ru
Priority to CN201880077331.1A priority patent/CN111417363B/zh
Priority to EP18869860.9A priority patent/EP3701909A4/en
Priority to JP2020543450A priority patent/JP7482781B2/ja
Priority to IL274267A priority patent/IL274267B1/en
Priority to AU2018355805A priority patent/AU2018355805A1/en
Priority to CA3080484A priority patent/CA3080484A1/en
Priority to US16/759,723 priority patent/US11654013B2/en
Publication of WO2019083350A1 publication Critical patent/WO2019083350A1/es
Publication of WO2019083350A4 publication Critical patent/WO2019083350A4/es
Priority to CONC2020/0006207A priority patent/CO2020006207A2/es

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/141—Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
    • A61F2002/0081—Special surfaces of prostheses, e.g. for improving ingrowth directly machined on the prosthetic surface, e.g. holes, grooves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
    • A61F2002/0086—Special surfaces of prostheses, e.g. for improving ingrowth for preferentially controlling or promoting the growth of specific types of cells or tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008—Fixation appliances for connecting prostheses to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001—Designing or manufacturing processes
    • A61F2240/002—Designing or making customized prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001—Designing or manufacturing processes
    • A61F2240/002—Designing or making customized prostheses
    • A61F2240/004—Using a positive or negative model, e.g. moulds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/006—Additional features; Implant or prostheses properties not otherwise provided for modular
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Abstract

El Implante Ocular Duosistema Multiceldas Nucleoreticular, consiste en una estructura esférica con longitud axial calculada y variable dependiendo de las necesidades que requiera la cavidad orbital ocular, compuesta de una malla de celdas con diseños alternativos que a su vez compone el Sistema M.M.M, en el que se facilita la sutura en cualquier técnica, ya sea en casos de evisceración o enucleación. Gracias a su diseño estructural multiceldas, favorece su colocación y disminuye el riesgo de migración, extrusión, exposición y extracción. Al ser una estructura con oquedades estructurales, brinda un mayor porcentaje del volumen para su vascularización, asimismo alberga en su interior un Sistema Núcleo Reticular Fibrovascular, el cual cuenta con una estructura basada en pluriniveles dotados de tejido microreticular y una comunicación intraniveles a base de filamentos; con capacidad para albergar medicamentos y/o tecnología por presentar un duosistema de dos piezas enroscables, pudiéndose fabricar en distintos diseños estructurales y materiales biocompatibles. El modelo C100 fabricado con ácido poliláctico (PLA), un material ideal para implantes, consta de 100 celdas ovaladas. Al ser un implante ocular ligero, evita la depresión por asentamiento o gravedad y es elaborable en cualquier medida.

Claims

REIVINDICACIONES MODIFICADAS recibidas por la oficina Internacional el 18 de abril de 2019 (18.04.2019)
1 .- Implante Ocular Duosistema Multiceldas Nucleoreticular, que técnicamente consiste en dos sistemas interrelacionados, el Sistema Multiceldas Muscular Motriz M.M.M. y el Sistema Núcleo Reticular Flbrovascular, N.R.F., conformados en primer orden por una estructura exterior que dispone de multiceldas para irrigación súbita de la vascularización, bordeadas por postes y nodos para sujeción de sutura; y un segundo sistema opcional constituido al Interior por un núcleo plurlnlvel de mlcroreticulas y filamentos que logran la vascularización y flbrovascularlzación.
2.- CANCELADA
3.- CANCELADA
4.- CANCELADA
5. -El Implante Ocular Duosistema Multiceldas Nucleoreticular de la reivindicación número 1 permite ser elaborado con cualquier tipo de material biocompatible, natural o sintético, tales como los cerámicos, metálicos, polímeros, orgánicos, vegetales, celulares, de la Industria espacial o cualesquiera otros.
6.- El Implante Ocular Duosistema Multiceldas Nucleoreticular de las reivindicaciones números 1 y 2.- puede ser fabricado bajo cualquier procedimiento de elaboración sea moldeado, vaciado, troquelado, Inyectado, presionado por vaciado, tejido, sublimado, por inducción celular, estereolltografía, o cualesquiera otra manera que la forma permita y compatible con los fines y funciones que la reivindicación 1 refieren.
7.- CANCELADA
8.- CANCELADA
9.- El Implante Ocular Duosistema Multiceldas Nucleoreticular de la reivindicación 1 .- en los puntos de intersección de los postes tiene nodos, los cuales permiten una suturaclón diagonal que complementa las otras suturas musculares, cada nodo es ¡dentlflcable en relación a la celda a que pertenece y su posición en la misma, lo cual permite anotar el registro clínico del paciente a detalle.
10.- CANCELADA
1 1 .- El Implante Ocular Duosistema Multiceldas Nucleoreticular de las reivindicaciones 1 .-,2.-,3.- y 4.- está dotado del sistema multiceldas siendo una de sus funciones multiplicar los métodos de 28 sutura, al tener condiciones y accesibilidad para que el cirujano cuente con libertad técnica de sujeción del implante, tanto en los casos de evisceración como de enucleación, ello mediante el establecimiento de postes y nodos, siendo los primeros fijaciones verticales u horizontales y los segundos diagonales, prestaciones que combinadas permiten evitar los riesgos de extrusión o migración del implante. El cirujano dispone de múltiples opciones de colocación del implante, existe una posición de colocación natural, misma que puede variar en los casos que el cirujano lo estime conveniente, sin que tal variación signifique menoscabo en las potencialidades del implante.
12.- CANCELADA
13.- CANCELADA
14.- El Implante Ocular Duosistema Multiceldas Nucleoreticular de las reivindicaciones 1 .-, 2.-, 3.-, 4.-, 5.- , 6.- y 7.- cuenta con un un núcleo que compone su sistema interior de filamentos y plataformas de niveles que establecen en su integridad una base para fibrovascularización con cualidades circulatorias y oxigenantes que logran un basamento de tejido orgánico vital primigenio que se integra con el sistema exterior.
15.- En el Implante Ocular Duosistema Multiceldas Nucleoreticular de las reivindicaciones 1 .-, 2.- , 3.-, 4.-, 5.- 6.- 7.- y 8.-, el sistema interior o nuclear, se encuentra fijo a la estructura exterior por unas superficies interiores que constituyen los pluriniveles microreticulares, que son un fino tejido que tiene la función de cimentar y permitir el flujo sanguíneo y oxigenación consecuente, todo ello distribuido en una estructura plurinivel, consistente en varias plataformas posicionadas con alineación a los paralelos, con la función de optimizar la resistencia estructural y a la vez logran la fibrovascularización con el complemento de los filamentos intraniveles.
16.- El Implante Ocular Duosistema Multiceldas Nucleoreticular de la reivindicación 1 .- y 8.- en la estructura interior o núcleo, está dotada de filamentos fibrovascularizables, se trata de fibras que se ubican entre cada plurinivel siendo cimentantes, conectivas y conductivas de flujo sanguíneo, proveen un excelente medio de fibrovascularización.
17.- CANCELADA.
18.- CANCELADA.
19.- CANCELADA. 29
20.- CANCELADA
21 .- CANCELADA.
22.- CANCELADA.
23.- CANCELADA.
24.- CANCELADA.
25.- CANCELADA.
26.- CANCELADA.
27.- CANCELADA
PCT/MX2018/000115 2017-10-27 2018-10-29 Implante ocular duosistema multiceldas nucleoreticular WO2019083350A1 (es)

Priority Applications (11)

Application Number Priority Date Filing Date Title
JP2020543450A JP7482781B2 (ja) 2017-10-27 2018-10-29 核網様体マルチセル二重システム眼インプラント
BR112020008294-5A BR112020008294A2 (pt) 2017-10-27 2018-10-29 implante ocular com sistema duplo multicelular nucleorreticular
RU2020115565A RU2020115565A (ru) 2017-10-27 2018-10-29 Многоячеистый двухсистемный глазной имплантат в виде сетчатого ядра
CN201880077331.1A CN111417363B (zh) 2017-10-27 2018-10-29 网状核多单元双系统眼部植入物
EP18869860.9A EP3701909A4 (en) 2017-10-27 2018-10-29 EYE IMPLANT WITH NUCLEORETICULAR DUAL MULTICELL SYSTEM
KR1020207013237A KR20200081389A (ko) 2017-10-27 2018-10-29 핵-망상 멀티-셀 듀얼 시스템 안구 임플란트
IL274267A IL274267B1 (en) 2017-10-27 2018-10-29 Ocular implant with dual multicellular nucleo-retinal system
US16/759,723 US11654013B2 (en) 2017-10-27 2018-10-29 Nucleo-reticular multi-cell dual-system eye implant
CA3080484A CA3080484A1 (en) 2017-10-27 2018-10-29 Nucleo-reticular multi-cell dual-system eye implant
AU2018355805A AU2018355805A1 (en) 2017-10-27 2018-10-29 Nucleo-reticular multi-cell dual-system ocular implant
CONC2020/0006207A CO2020006207A2 (es) 2017-10-27 2020-05-21 Implante ocular duosistema multiceldas nucleoreticular

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MX2017013845A MX2017013845A (es) 2017-10-27 2017-10-27 Implante ocular duosistema multiceldas nucleoreticular.
MXMX/A/2017/013845 2017-10-27

Publications (2)

Publication Number Publication Date
WO2019083350A1 WO2019083350A1 (es) 2019-05-02
WO2019083350A4 true WO2019083350A4 (es) 2019-06-20

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PCT/MX2018/000115 WO2019083350A1 (es) 2017-10-27 2018-10-29 Implante ocular duosistema multiceldas nucleoreticular

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US (1) US11654013B2 (es)
EP (1) EP3701909A4 (es)
KR (1) KR20200081389A (es)
CN (1) CN111417363B (es)
AU (1) AU2018355805A1 (es)
BR (1) BR112020008294A2 (es)
CA (1) CA3080484A1 (es)
CL (1) CL2020001117A1 (es)
CO (1) CO2020006207A2 (es)
IL (1) IL274267B1 (es)
MX (1) MX2017013845A (es)
RU (1) RU2020115565A (es)
WO (1) WO2019083350A1 (es)

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FR3083080B1 (fr) * 2018-06-29 2021-08-27 France Chirurgie Instr Sas Implant orbital comportant des fenetres traversantes pour sutures

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CL2020001117A1 (es) 2020-08-21
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CN111417363A (zh) 2020-07-14
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