CA3078739A1 - Treating dementia with visual stimulation to synch gamma oscillations in brain - Google Patents

Treating dementia with visual stimulation to synch gamma oscillations in brain

Info

Publication number
CA3078739A1
CA3078739A1 CA3078739A CA3078739A CA3078739A1 CA 3078739 A1 CA3078739 A1 CA 3078739A1 CA 3078739 A CA3078739 A CA 3078739A CA 3078739 A CA3078739 A CA 3078739A CA 3078739 A1 CA3078739 A1 CA 3078739A1
Authority
CA
Canada
Prior art keywords
subject
visual stimuli
mice
chronic
chronic visual
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3078739A
Other languages
English (en)
French (fr)
Inventor
Chinnakkaruppan Adaikkan
Li-Huei Tsai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of CA3078739A1 publication Critical patent/CA3078739A1/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0618Psychological treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0622Optical stimulation for exciting neural tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0022Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the tactile sense, e.g. vibrations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0027Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the hearing sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0044Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the sight sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0693Brain, cerebrum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0626Monitoring, verifying, controlling systems and methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/063Radiation therapy using light comprising light transmitting means, e.g. optical fibres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0635Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645Applicators worn by the patient
    • A61N2005/0647Applicators worn by the patient the applicator adapted to be worn on the head
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0635Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645Applicators worn by the patient
    • A61N2005/0647Applicators worn by the patient the applicator adapted to be worn on the head
    • A61N2005/0648Applicators worn by the patient the applicator adapted to be worn on the head the light being directed to the eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/065Light sources therefor
    • A61N2005/0651Diodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0664Details
    • A61N2005/0667Filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Psychology (AREA)
  • Developmental Disabilities (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Biophysics (AREA)
  • Social Psychology (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Radiation-Therapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA3078739A 2017-10-10 2018-10-10 Treating dementia with visual stimulation to synch gamma oscillations in brain Pending CA3078739A1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201762570250P 2017-10-10 2017-10-10
US62/570,250 2017-10-10
US201762570929P 2017-10-11 2017-10-11
US62/570,929 2017-10-11
USPCT/US2018/051785 2018-09-19
PCT/US2018/055258 WO2019075094A1 (en) 2017-10-10 2018-10-10 TREATMENT OF DEMENTIA BY VISUAL STIMULATION TO INDUCE SYNCHRONIZED GAMA OSCILLATIONS IN THE BRAIN

Publications (1)

Publication Number Publication Date
CA3078739A1 true CA3078739A1 (en) 2019-04-18

Family

ID=83459525

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3078739A Pending CA3078739A1 (en) 2017-10-10 2018-10-10 Treating dementia with visual stimulation to synch gamma oscillations in brain

Country Status (7)

Country Link
EP (1) EP3694593A4 (ko)
JP (1) JP2020536643A (ko)
KR (2) KR20200086277A (ko)
CN (1) CN111655319A (ko)
AU (2) AU2018347366B2 (ko)
CA (1) CA3078739A1 (ko)
WO (1) WO2019075094A1 (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230095907A1 (en) 2019-10-18 2023-03-30 Institute Of Science And Technology Austria Stimulation of neuronal plasticity
KR20210053631A (ko) * 2019-11-04 2021-05-12 한국과학기술원 가시광선을 이용하여 감마 대역의 뇌파를 활성화하는 방법 및 이를 위한 시각 자극 제공 장치
KR102400319B1 (ko) * 2021-12-31 2022-05-24 (주)리솔 객체의 복수의 뇌 영역에서 동기화된 진동을 동조시킴으로써, 뇌를 자극하는 장치 및 방법
CN116407766A (zh) 2021-12-31 2023-07-11 株式会社利率 定制型经颅交流电刺激装置及方法
KR102425066B1 (ko) * 2022-03-25 2022-07-28 (주)리솔 실시간 eeg 신호 모니터링을 기초로, 뇌에서 동기화된 뇌파진동을 동조시키는 맞춤형 경두개교류전기자극 장치 및 방법
KR102577515B1 (ko) 2022-11-21 2023-09-12 이종설 파동자극 생성기기

Family Cites Families (17)

* Cited by examiner, † Cited by third party
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ES2136654T3 (es) * 1991-12-06 1999-12-01 Max Planck Gesellschaft Herramientas para el diagnostico y tratamiento de la enfermedad de alzheimer.
JP3648802B2 (ja) * 1994-09-27 2005-05-18 松下電工株式会社 光治療用高照度光照射装置
EP1814630A4 (en) * 2004-11-15 2008-05-07 Christopher Decharms APPLICATIONS FOR NERVE BEND STIMULATION BY LIGHT
US20080181882A1 (en) * 2006-11-15 2008-07-31 The University Of Pennsylvania Neurgulin 1 (NRG1) - ErbB4 signaling as a target for the treatment of schizophrenia
WO2008147958A1 (en) * 2007-05-25 2008-12-04 Thomas Jefferson University Method of treatment to improve concentration and/or memory in a subject in need thereof
DE102008012669B8 (de) * 2008-03-05 2011-03-03 Anm Adaptive Neuromodulation Gmbh Vorrichtung und Verfahren zur visuellen Stimulation
ITRM20090027A1 (it) * 2009-01-26 2010-07-27 Alain Rocco Apparato di stimolazione per il trattamento del dolore e relativo metodo di funzionamento.
WO2012024243A1 (en) * 2010-08-16 2012-02-23 Photothera, Inc. Minimally invasive low level light therapy for neurological disorders
WO2013061597A1 (ja) * 2011-10-25 2013-05-02 学校法人金沢医科大学 認知症状やうつ様症状改善のための光照射装置、この光照射装置を備えた部屋、及び認知症状やうつ様症状改善のための照明器具
US9272118B1 (en) * 2012-03-02 2016-03-01 George Acton Methods for treating brain malfunctions
US20150337030A1 (en) * 2012-05-31 2015-11-26 The Trustees Of Columbia University In The City Of New York Methods to treat alzheimer's disease using apoe inhibitors
US20140303025A1 (en) * 2013-03-15 2014-10-09 The Translational Genomics Research Institute Methods for the diagnosis and prognosis of neurodegenerative diseases
EP3065818B1 (en) * 2013-11-04 2020-05-27 Phoenix NeuroStim Therapeutics, LLC Device for the treatment of central nervous system conditions using sensory stimulus
WO2015149170A1 (en) * 2014-03-31 2015-10-08 Functional Neuromodulation, Inc. Systems and methods for determining a trajectory for a brain stimulation lead
EP3180080B1 (en) * 2014-08-14 2021-01-06 Functional Neuromodulation, Inc. Brain stimulation system including multiple stimulation modes
KR102603963B1 (ko) * 2015-11-24 2023-11-20 메사추세츠 인스티튜트 오브 테크놀로지 치매를 예방, 경감 및/또는 치료하기 위한 시스템 및 방법
WO2017172728A1 (en) * 2016-03-28 2017-10-05 Duke University Systems and methods for brain stimulation

Also Published As

Publication number Publication date
JP2020536643A (ja) 2020-12-17
EP3694593A1 (en) 2020-08-19
KR20230015501A (ko) 2023-01-31
KR20200086277A (ko) 2020-07-16
AU2022271389A1 (en) 2022-12-15
AU2018347366B2 (en) 2022-09-15
AU2018347366A1 (en) 2020-04-23
WO2019075094A1 (en) 2019-04-18
EP3694593A4 (en) 2021-07-21
CN111655319A (zh) 2020-09-11

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