EP3694593A4 - TREATMENT OF DEMENTIA BY VISUAL STIMULATION TO INDUCE SYNCHRONIZED GAMA OSCILLATIONS IN THE BRAIN - Google Patents

TREATMENT OF DEMENTIA BY VISUAL STIMULATION TO INDUCE SYNCHRONIZED GAMA OSCILLATIONS IN THE BRAIN Download PDF

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Publication number
EP3694593A4
EP3694593A4 EP18866752.1A EP18866752A EP3694593A4 EP 3694593 A4 EP3694593 A4 EP 3694593A4 EP 18866752 A EP18866752 A EP 18866752A EP 3694593 A4 EP3694593 A4 EP 3694593A4
Authority
EP
European Patent Office
Prior art keywords
synch
brain
visual stimulation
treating dementia
gamma oscillations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP18866752.1A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP3694593A1 (en
Inventor
Chinnakkaruppan Adaikkan
Li-Huei Tsai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
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Massachusetts Institute of Technology
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Filing date
Publication date
Priority claimed from PCT/US2018/051785 external-priority patent/WO2019074637A1/en
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of EP3694593A1 publication Critical patent/EP3694593A1/en
Publication of EP3694593A4 publication Critical patent/EP3694593A4/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0618—Psychological treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0622—Optical stimulation for exciting neural tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0022—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the tactile sense, e.g. vibrations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0027—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the hearing sense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0044—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the sight sense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0693—Brain, cerebrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0626—Monitoring, verifying, controlling systems and methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/063—Radiation therapy using light comprising light transmitting means, e.g. optical fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645—Applicators worn by the patient
    • A61N2005/0647—Applicators worn by the patient the applicator adapted to be worn on the head
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645—Applicators worn by the patient
    • A61N2005/0647—Applicators worn by the patient the applicator adapted to be worn on the head
    • A61N2005/0648—Applicators worn by the patient the applicator adapted to be worn on the head the light being directed to the eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/065—Light sources therefor
    • A61N2005/0651—Diodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0664—Details
    • A61N2005/0667—Filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Psychology (AREA)
  • Developmental Disabilities (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Biophysics (AREA)
  • Social Psychology (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP18866752.1A 2017-10-10 2018-10-10 TREATMENT OF DEMENTIA BY VISUAL STIMULATION TO INDUCE SYNCHRONIZED GAMA OSCILLATIONS IN THE BRAIN Pending EP3694593A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762570250P 2017-10-10 2017-10-10
US201762570929P 2017-10-11 2017-10-11
PCT/US2018/051785 WO2019074637A1 (en) 2017-10-10 2018-09-19 SYSTEMS AND METHODS FOR PREVENTION, MITIGATION AND / OR TREATMENT OF DEMENTIA
PCT/US2018/055258 WO2019075094A1 (en) 2017-10-10 2018-10-10 TREATMENT OF DEMENTIA BY VISUAL STIMULATION TO INDUCE SYNCHRONIZED GAMA OSCILLATIONS IN THE BRAIN

Publications (2)

Publication Number Publication Date
EP3694593A1 EP3694593A1 (en) 2020-08-19
EP3694593A4 true EP3694593A4 (en) 2021-07-21

Family

ID=83459525

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18866752.1A Pending EP3694593A4 (en) 2017-10-10 2018-10-10 TREATMENT OF DEMENTIA BY VISUAL STIMULATION TO INDUCE SYNCHRONIZED GAMA OSCILLATIONS IN THE BRAIN

Country Status (7)

Country Link
EP (1) EP3694593A4 (ko)
JP (1) JP2020536643A (ko)
KR (2) KR20230015501A (ko)
CN (1) CN111655319A (ko)
AU (2) AU2018347366B2 (ko)
CA (1) CA3078739A1 (ko)
WO (1) WO2019075094A1 (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114555166A (zh) 2019-10-18 2022-05-27 奥地利科学技术研究所 神经元可塑性的刺激
KR20210053631A (ko) * 2019-11-04 2021-05-12 한국과학기술원 가시광선을 이용하여 감마 대역의 뇌파를 활성화하는 방법 및 이를 위한 시각 자극 제공 장치
KR102425066B1 (ko) * 2022-03-25 2022-07-28 (주)리솔 실시간 eeg 신호 모니터링을 기초로, 뇌에서 동기화된 뇌파진동을 동조시키는 맞춤형 경두개교류전기자극 장치 및 방법
CN116407766A (zh) 2021-12-31 2023-07-11 株式会社利率 定制型经颅交流电刺激装置及方法
KR102400319B1 (ko) * 2021-12-31 2022-05-24 (주)리솔 객체의 복수의 뇌 영역에서 동기화된 진동을 동조시킴으로써, 뇌를 자극하는 장치 및 방법
KR102577515B1 (ko) 2022-11-21 2023-09-12 이종설 파동자극 생성기기

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008147958A1 (en) * 2007-05-25 2008-12-04 Thomas Jefferson University Method of treatment to improve concentration and/or memory in a subject in need thereof
ITRM20090027A1 (it) * 2009-01-26 2010-07-27 Alain Rocco Apparato di stimolazione per il trattamento del dolore e relativo metodo di funzionamento.
WO2015066679A2 (en) * 2013-11-04 2015-05-07 Metzger Steven Treatment of central nervous system conditions using sensory stimulus
WO2015149170A1 (en) * 2014-03-31 2015-10-08 Functional Neuromodulation, Inc. Systems and methods for determining a trajectory for a brain stimulation lead
US9272118B1 (en) * 2012-03-02 2016-03-01 George Acton Methods for treating brain malfunctions
US20170143934A1 (en) * 2015-11-24 2017-05-25 Li-Huei Tsai Systems and methods for preventing, mitigating, and/or treating dementia

Family Cites Families (11)

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DK0618968T3 (da) * 1991-12-06 2000-04-10 Max Planck Gesellschaft Midler til diagnostisering og behandling af Alzheimer's sygdom
JP3648802B2 (ja) * 1994-09-27 2005-05-18 松下電工株式会社 光治療用高照度光照射装置
JP2008520280A (ja) * 2004-11-15 2008-06-19 デチャームス，クリストファー 光を使用した神経組織の刺激の適用
US20080181882A1 (en) * 2006-11-15 2008-07-31 The University Of Pennsylvania Neurgulin 1 (NRG1) - ErbB4 signaling as a target for the treatment of schizophrenia
DE102008012669B8 (de) * 2008-03-05 2011-03-03 Anm Adaptive Neuromodulation Gmbh Vorrichtung und Verfahren zur visuellen Stimulation
WO2012024243A1 (en) * 2010-08-16 2012-02-23 Photothera, Inc. Minimally invasive low level light therapy for neurological disorders
WO2013061597A1 (ja) * 2011-10-25 2013-05-02 学校法人金沢医科大学 認知症状やうつ様症状改善のための光照射装置、この光照射装置を備えた部屋、及び認知症状やうつ様症状改善のための照明器具
WO2013181618A2 (en) * 2012-05-31 2013-12-05 The Trustees Of Columbia University In The City Of New York Methods to treat alzheimer's disease using apoe inhibitors
US20140303025A1 (en) * 2013-03-15 2014-10-09 The Translational Genomics Research Institute Methods for the diagnosis and prognosis of neurodegenerative diseases
EP3180080B1 (en) * 2014-08-14 2021-01-06 Functional Neuromodulation, Inc. Brain stimulation system including multiple stimulation modes
WO2017172728A1 (en) * 2016-03-28 2017-10-05 Duke University Systems and methods for brain stimulation

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008147958A1 (en) * 2007-05-25 2008-12-04 Thomas Jefferson University Method of treatment to improve concentration and/or memory in a subject in need thereof
ITRM20090027A1 (it) * 2009-01-26 2010-07-27 Alain Rocco Apparato di stimolazione per il trattamento del dolore e relativo metodo di funzionamento.
US9272118B1 (en) * 2012-03-02 2016-03-01 George Acton Methods for treating brain malfunctions
WO2015066679A2 (en) * 2013-11-04 2015-05-07 Metzger Steven Treatment of central nervous system conditions using sensory stimulus
WO2015149170A1 (en) * 2014-03-31 2015-10-08 Functional Neuromodulation, Inc. Systems and methods for determining a trajectory for a brain stimulation lead
US20170143934A1 (en) * 2015-11-24 2017-05-25 Li-Huei Tsai Systems and methods for preventing, mitigating, and/or treating dementia

Also Published As

Publication number Publication date
KR20230015501A (ko) 2023-01-31
EP3694593A1 (en) 2020-08-19
JP2020536643A (ja) 2020-12-17
CN111655319A (zh) 2020-09-11
AU2018347366B2 (en) 2022-09-15
AU2018347366A1 (en) 2020-04-23
CA3078739A1 (en) 2019-04-18
WO2019075094A1 (en) 2019-04-18
AU2022271389A1 (en) 2022-12-15
KR20200086277A (ko) 2020-07-16

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