CA3072484C - An injection molded microfluidic/fluidic cartridge integrated with silicon-based sensor - Google Patents
An injection molded microfluidic/fluidic cartridge integrated with silicon-based sensor Download PDFInfo
- Publication number
- CA3072484C CA3072484C CA3072484A CA3072484A CA3072484C CA 3072484 C CA3072484 C CA 3072484C CA 3072484 A CA3072484 A CA 3072484A CA 3072484 A CA3072484 A CA 3072484A CA 3072484 C CA3072484 C CA 3072484C
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- plastic substrate
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0689—Sealing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0877—Flow chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
- B01L2400/027—Drop detachment mechanisms of single droplets from nozzles or pins electrostatic forces between substrate and tip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
- B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762553614P | 2017-09-01 | 2017-09-01 | |
| US62/553,614 | 2017-09-01 | ||
| PCT/US2018/049039 WO2019046690A1 (en) | 2017-09-01 | 2018-08-31 | INTEGRATED INJECTION MICROFLUIDIC / FLUID CARTRIDGE WITH SILICON-BASED SENSOR |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA3072484A1 CA3072484A1 (en) | 2019-03-07 |
| CA3072484C true CA3072484C (en) | 2022-05-24 |
Family
ID=65517621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3072484A Active CA3072484C (en) | 2017-09-01 | 2018-08-31 | An injection molded microfluidic/fluidic cartridge integrated with silicon-based sensor |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11007523B2 (enExample) |
| EP (2) | EP3676010B1 (enExample) |
| JP (2) | JP7169345B2 (enExample) |
| KR (1) | KR102387367B1 (enExample) |
| CN (1) | CN111050913B (enExample) |
| AU (1) | AU2018325527B2 (enExample) |
| CA (1) | CA3072484C (enExample) |
| TW (1) | TWI758537B (enExample) |
| WO (1) | WO2019046690A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019055007A1 (en) * | 2017-09-14 | 2019-03-21 | Hewlett-Packard Development Company, L.P. | MICROFLUIDIC HOUSING |
| CN111855083B (zh) * | 2019-04-19 | 2021-10-22 | 厦门大学 | 具有液流控制阀的微流控芯片的模拟检测装置及方法 |
| DE102019112254A1 (de) * | 2019-05-10 | 2020-11-12 | Leonhard Kurz Stiftung & Co. Kg | Mikrofluidische Anordnung, Verfahren zu deren Herstellung und Messsystem umfassend die mikrofluidische Anordnung sowie Verwendung |
| EP3965930A1 (de) | 2019-05-10 | 2022-03-16 | LEONHARD KURZ Stiftung & Co. KG | Mikrofluidische anordnung, verfahren zu deren herstellung und messsystem umfassend die mikrofluidische anordnung sowie verwendung |
| SG11202012495YA (en) * | 2019-05-21 | 2021-01-28 | Illumina Inc | Sensors having an active surface |
| CN111013676A (zh) * | 2019-12-17 | 2020-04-17 | 江苏圣极基因科技有限公司 | 一种液滴制备方法及微流控芯片 |
| US11808569B2 (en) * | 2020-03-22 | 2023-11-07 | Strike Photonics, Inc. | Waveguide enhanced analyte detection apparatus |
| FR3114092B1 (fr) * | 2020-09-17 | 2022-08-26 | Commissariat Energie Atomique | Procédé de fabrication d'un dispositif micro-fluidique et dispositif fabriqué par ledit procédé |
| TW202231156A (zh) | 2021-01-15 | 2022-08-01 | 美商伊路米納有限公司 | 實現感測器頂側打線接合 |
| CA3223107A1 (en) * | 2021-11-05 | 2023-05-11 | Ravi Billa | Sensor having an active surface |
| WO2024173811A1 (en) * | 2023-02-17 | 2024-08-22 | Twist Bioscience Corporation | Vertical flow cell for biomolecule extraction |
| KR20240177093A (ko) | 2023-06-19 | 2024-12-27 | (주)페블아이 | 현장검사를 위한 휴대용 바이오칩 |
| DE102023126573A1 (de) * | 2023-09-28 | 2025-04-03 | Bürkert Werke GmbH & Co. KG | Einweg-Fluidführungsbaugruppe, Verfahren zur Herstellung der Einweg-Fluidführungsbaugruppe, mikrofluidische Vorrichtung mit Einweg-Fluidführungsbaugruppe sowie Proteindefektdiagnosevorrichtung |
| WO2025242595A1 (en) * | 2024-05-21 | 2025-11-27 | Lex diagnostics Ltd. | Fluidic cartridges with component-free valves |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1192097C (zh) * | 1995-03-10 | 2005-03-09 | 梅索磅秤技术有限公司 | 多阵列、多特异性的电化学发光检验 |
| JP2002543403A (ja) * | 1999-05-03 | 2002-12-17 | カンション アクティーゼルスカブ | 液体中において物質の存在を検出するための方法及びセンサ、並びにセンサの製造方法 |
| EP1065378B1 (en) * | 1999-06-28 | 2002-04-03 | California Institute of Technology | Microfabricated elastomeric valve and pump systems |
| US6790599B1 (en) * | 1999-07-15 | 2004-09-14 | Microbionics, Inc. | Microfluidic devices and manufacture thereof |
| AU2002230524A1 (en) * | 2000-11-16 | 2002-05-27 | California Institute Of Technology | Apparatus and methods for conducting assays and high throughput screening |
| NL1016779C2 (nl) * | 2000-12-02 | 2002-06-04 | Cornelis Johannes Maria V Rijn | Matrijs, werkwijze voor het vervaardigen van precisieproducten met behulp van een matrijs, alsmede precisieproducten, in het bijzonder microzeven en membraanfilters, vervaardigd met een dergelijke matrijs. |
| JP3990909B2 (ja) * | 2001-12-26 | 2007-10-17 | 旭化成株式会社 | 化学反応用カートリッジ |
| US6878271B2 (en) * | 2002-09-09 | 2005-04-12 | Cytonome, Inc. | Implementation of microfluidic components in a microfluidic system |
| US7455770B2 (en) * | 2002-09-09 | 2008-11-25 | Cytonome, Inc. | Implementation of microfluidic components in a microfluidic system |
| US7842234B2 (en) * | 2002-12-02 | 2010-11-30 | Epocal Inc. | Diagnostic devices incorporating fluidics and methods of manufacture |
| KR101216828B1 (ko) * | 2002-12-30 | 2013-01-04 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 병원균 검출과 분석을 위한 방법과 기구 |
| CN1867795B (zh) * | 2003-08-11 | 2010-12-08 | 加州理工学院 | 微流体的大规模集成 |
| NL1024578C2 (nl) * | 2003-10-21 | 2005-04-22 | Univ Delft Tech | Inrichting voor het uitvoeren van een reactie. |
| US20060002817A1 (en) * | 2004-06-30 | 2006-01-05 | Sebastian Bohm | Flow modulation devices |
| US7832429B2 (en) * | 2004-10-13 | 2010-11-16 | Rheonix, Inc. | Microfluidic pump and valve structures and fabrication methods |
| KR20080044263A (ko) * | 2005-09-09 | 2008-05-20 | 코닌클리케 필립스 일렉트로닉스 엔.브이. | 마이크로시스템 제작 방법, 그러한 마이크로시스템, 그러한마이크로시스템을 포함하는 포일의 스택, 그러한마이크로시스템을 포함하는 전자 디바이스, 및 그러한 전자디바이스의 사용 |
| NZ567587A (en) * | 2005-10-26 | 2010-11-26 | Gen Electric | Methods and systems for delivery of fluidic samples to sensor arrays |
| WO2008127269A2 (en) * | 2006-08-15 | 2008-10-23 | The Government Of The United States Of America, As Represented By The Secretary Of The Navy | A method and apparatus for attaching a fluid cell to a planar substrate |
| EP2091646A1 (en) * | 2006-11-09 | 2009-08-26 | The Board of Trustees for the University of Illinois | Photonic crystal sensors with integrated fluid containment structure |
| DK2215209T3 (en) * | 2007-10-30 | 2018-09-03 | Complete Genomics Inc | DEVICE FOR HIGH-THROUGHPUT SEQUENCE OF NUCLEIC ACIDS |
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| CN105624020B (zh) * | 2014-11-07 | 2017-11-03 | 深圳华大基因研究院 | 用于检测dna片段的碱基序列的微流控芯片 |
| CN105013550B (zh) * | 2015-07-09 | 2016-08-24 | 清华大学深圳研究生院 | 微流控芯片夹具和微流控芯片 |
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| CN206184464U (zh) * | 2016-11-25 | 2017-05-24 | 黑龙江东方学院 | 自动化的微流控接收装置 |
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2018
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- 2018-08-31 EP EP18852532.3A patent/EP3676010B1/en active Active
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2022
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| EP4382474A3 (en) | 2024-09-25 |
| US11007523B2 (en) | 2021-05-18 |
| EP3676010A1 (en) | 2020-07-08 |
| KR102387367B1 (ko) | 2022-04-14 |
| EP4382474A2 (en) | 2024-06-12 |
| CN111050913B (zh) | 2022-04-12 |
| WO2019046690A1 (en) | 2019-03-07 |
| AU2018325527A1 (en) | 2020-02-27 |
| JP7169345B2 (ja) | 2022-11-10 |
| US20190070606A1 (en) | 2019-03-07 |
| CN111050913A (zh) | 2020-04-21 |
| EP3676010A4 (en) | 2021-09-08 |
| TWI758537B (zh) | 2022-03-21 |
| TW201928331A (zh) | 2019-07-16 |
| JP2023002784A (ja) | 2023-01-10 |
| JP2020532722A (ja) | 2020-11-12 |
| KR20200042534A (ko) | 2020-04-23 |
| CA3072484A1 (en) | 2019-03-07 |
| AU2018325527B2 (en) | 2021-09-16 |
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