CA3070998A1 - Enhanced chimeric antigen receptors and use thereof - Google Patents

Enhanced chimeric antigen receptors and use thereof

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Publication number
CA3070998A1
CA3070998A1 CA3070998A CA3070998A CA3070998A1 CA 3070998 A1 CA3070998 A1 CA 3070998A1 CA 3070998 A CA3070998 A CA 3070998A CA 3070998 A CA3070998 A CA 3070998A CA 3070998 A1 CA3070998 A1 CA 3070998A1
Authority
CA
Canada
Prior art keywords
car
cell
seq
amino acid
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3070998A
Other languages
English (en)
French (fr)
Inventor
Sonny Oon Ang
Enli LIU
Elizabeth SHPALL
Katy REZVANI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
University of Texas System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Texas System filed Critical University of Texas System
Publication of CA3070998A1 publication Critical patent/CA3070998A1/en
Pending legal-status Critical Current

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    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
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    • C12N15/52—Genes encoding for enzymes or proenzymes
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    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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CA3070998A 2017-07-25 2018-07-25 Enhanced chimeric antigen receptors and use thereof Pending CA3070998A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762536934P 2017-07-25 2017-07-25
US62/536,934 2017-07-25
PCT/US2018/043779 WO2019023396A1 (en) 2017-07-25 2018-07-25 ENHANCED CHIMERIC ANTIGENIC RECEPTORS AND USES THEREOF

Publications (1)

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CA3070998A1 true CA3070998A1 (en) 2019-01-31

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CA3070998A Pending CA3070998A1 (en) 2017-07-25 2018-07-25 Enhanced chimeric antigen receptors and use thereof

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US (1) US20240336699A1 (enExample)
EP (2) EP4582146A2 (enExample)
JP (2) JP2020530989A (enExample)
KR (1) KR20200032174A (enExample)
CN (2) CN118206655A (enExample)
AU (1) AU2018306307B2 (enExample)
CA (1) CA3070998A1 (enExample)
TW (1) TW201908335A (enExample)
WO (1) WO2019023396A1 (enExample)

Families Citing this family (25)

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WO2020106621A1 (en) * 2018-11-19 2020-05-28 Board Of Regents, The University Of Texas System A modular, polycistronic vector for car and tcr transduction
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