CA3067637A1 - Assessing transplant complication risk with total cell-free dna - Google Patents
Assessing transplant complication risk with total cell-free dna Download PDFInfo
- Publication number
- CA3067637A1 CA3067637A1 CA3067637A CA3067637A CA3067637A1 CA 3067637 A1 CA3067637 A1 CA 3067637A1 CA 3067637 A CA3067637 A CA 3067637A CA 3067637 A CA3067637 A CA 3067637A CA 3067637 A1 CA3067637 A1 CA 3067637A1
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- dna
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/101—Sanger sequencing method, i.e. oligonucleotide sequencing using primer elongation and dideoxynucleotides as chain terminators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762522533P | 2017-06-20 | 2017-06-20 | |
| US62/522,533 | 2017-06-20 | ||
| US201762572556P | 2017-10-15 | 2017-10-15 | |
| US62/572,556 | 2017-10-15 | ||
| PCT/US2018/038598 WO2018237075A1 (en) | 2017-06-20 | 2018-06-20 | Assessing transplant complication risk with total cell-free dna |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3067637A1 true CA3067637A1 (en) | 2018-12-27 |
Family
ID=64735781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3067637A Pending CA3067637A1 (en) | 2017-06-20 | 2018-06-20 | Assessing transplant complication risk with total cell-free dna |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11773434B2 (enExample) |
| EP (2) | EP4488387A3 (enExample) |
| JP (1) | JP2020524519A (enExample) |
| CN (1) | CN110945136A (enExample) |
| AU (2) | AU2018288832B2 (enExample) |
| CA (1) | CA3067637A1 (enExample) |
| IL (1) | IL271460A (enExample) |
| WO (1) | WO2018237075A1 (enExample) |
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| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| CA3207599A1 (en) | 2010-05-18 | 2011-11-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| BR112013020220B1 (pt) | 2011-02-09 | 2020-03-17 | Natera, Inc. | Método para determinar o estado de ploidia de um cromossomo em um feto em gestação |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| EP3134541B1 (en) | 2014-04-21 | 2020-08-19 | Natera, Inc. | Detecting copy number variations (cnv) of chromosomal segments in cancer |
| US20180173846A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| US11479812B2 (en) | 2015-05-11 | 2022-10-25 | Natera, Inc. | Methods and compositions for determining ploidy |
| RU2760913C2 (ru) | 2016-04-15 | 2021-12-01 | Натера, Инк. | Способы выявления рака легкого |
| WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| US12084720B2 (en) | 2017-12-14 | 2024-09-10 | Natera, Inc. | Assessing graft suitability for transplantation |
| US12024738B2 (en) | 2018-04-14 | 2024-07-02 | Natera, Inc. | Methods for cancer detection and monitoring |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| WO2020206290A1 (en) * | 2019-04-03 | 2020-10-08 | The Medical College Of Wisconsin, Inc. | Methods for assessing risk using total cell-free dna |
| US11931674B2 (en) | 2019-04-04 | 2024-03-19 | Natera, Inc. | Materials and methods for processing blood samples |
| WO2020247263A1 (en) | 2019-06-06 | 2020-12-10 | Natera, Inc. | Methods for detecting immune cell dna and monitoring immune system |
| CN111667883B (zh) * | 2020-06-03 | 2021-01-22 | 四川大学 | 一种基于复合微单倍型焦磷酸测序图谱解析的法医学混合dna的分析方法 |
| US20230399697A1 (en) * | 2020-11-09 | 2023-12-14 | The Medical College Of Wisconsin, Inc. | Assessing risk with pre-operative total cell-free dna |
| WO2025079958A1 (ko) * | 2023-10-11 | 2025-04-17 | 고려대학교 산학협력단 | 높은 처리량의 돌연변이 특이적 아답터 리게이션 방법 |
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-
2018
- 2018-06-20 CA CA3067637A patent/CA3067637A1/en active Pending
- 2018-06-20 WO PCT/US2018/038598 patent/WO2018237075A1/en not_active Ceased
- 2018-06-20 CN CN201880048495.1A patent/CN110945136A/zh active Pending
- 2018-06-20 JP JP2019571052A patent/JP2020524519A/ja active Pending
- 2018-06-20 US US16/623,707 patent/US11773434B2/en active Active
- 2018-06-20 EP EP24198235.4A patent/EP4488387A3/en active Pending
- 2018-06-20 AU AU2018288832A patent/AU2018288832B2/en active Active
- 2018-06-20 EP EP18820195.8A patent/EP3642353B1/en active Active
-
2019
- 2019-12-16 IL IL271460A patent/IL271460A/en unknown
-
2023
- 2023-06-28 US US18/343,097 patent/US20240026437A1/en active Pending
-
2025
- 2025-06-05 AU AU2025204208A patent/AU2025204208A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3642353B1 (en) | 2025-03-05 |
| CN110945136A (zh) | 2020-03-31 |
| AU2018288832A1 (en) | 2020-01-16 |
| IL271460A (en) | 2020-01-30 |
| US20240026437A1 (en) | 2024-01-25 |
| EP3642353A1 (en) | 2020-04-29 |
| WO2018237075A1 (en) | 2018-12-27 |
| EP4488387A2 (en) | 2025-01-08 |
| EP3642353C0 (en) | 2025-03-05 |
| US11773434B2 (en) | 2023-10-03 |
| AU2018288832B2 (en) | 2025-03-06 |
| EP3642353A4 (en) | 2021-02-24 |
| EP4488387A3 (en) | 2025-07-23 |
| AU2025204208A1 (en) | 2025-06-26 |
| JP2020524519A (ja) | 2020-08-20 |
| US20210139969A1 (en) | 2021-05-13 |
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