CA3058081C - MICROFLUID DEVICE FOR ANALYTE DETECTION - Google Patents

MICROFLUID DEVICE FOR ANALYTE DETECTION

Info

Publication number
CA3058081C
CA3058081C CA3058081A CA3058081A CA3058081C CA 3058081 C CA3058081 C CA 3058081C CA 3058081 A CA3058081 A CA 3058081A CA 3058081 A CA3058081 A CA 3058081A CA 3058081 C CA3058081 C CA 3058081C
Authority
CA
Canada
Prior art keywords
microfluidic device
analyte
chamber
chambers
capture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3058081A
Other languages
English (en)
French (fr)
Other versions
CA3058081A1 (en
Inventor
Robert Forster
Elaine Spain
Kellie Adamson
Eadaoin Carthy
David Boyle
Original Assignee
Dublin City University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dublin City University filed Critical Dublin City University
Publication of CA3058081A1 publication Critical patent/CA3058081A1/en
Application granted granted Critical
Publication of CA3058081C publication Critical patent/CA3058081C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
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    • B01L3/502746Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
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    • G01N27/04Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
    • G01N27/06Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
    • G01N27/07Construction of measuring vessels; Electrodes therefor
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    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
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    • GPHYSICS
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    • G01N33/577Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
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    • G01N35/00069Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
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    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
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    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
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    • B01L2400/0677Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
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    • G01N2333/37Assays involving biological materials from specific organisms or of a specific nature from fungi

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Fluid Mechanics (AREA)
  • Electrochemistry (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA3058081A 2017-04-03 2018-03-28 MICROFLUID DEVICE FOR ANALYTE DETECTION Active CA3058081C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1705328.1A GB2561173A (en) 2017-04-03 2017-04-03 Microfluidic device for detection of analytes
GB1705328.1 2017-04-03
PCT/EP2018/057997 WO2018184957A1 (en) 2017-04-03 2018-03-28 Microfluidic device for detection of analytes

Publications (2)

Publication Number Publication Date
CA3058081A1 CA3058081A1 (en) 2018-10-11
CA3058081C true CA3058081C (en) 2024-10-01

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CA3058081A Active CA3058081C (en) 2017-04-03 2018-03-28 MICROFLUID DEVICE FOR ANALYTE DETECTION

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Country Link
US (2) US11406976B2 (https=)
EP (1) EP3606667B1 (https=)
JP (1) JP7202664B2 (https=)
AU (2) AU2018247760B2 (https=)
CA (1) CA3058081C (https=)
ES (1) ES2992414T3 (https=)
GB (1) GB2561173A (https=)
PL (1) PL3606667T3 (https=)
WO (1) WO2018184957A1 (https=)

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WO2019126388A1 (en) * 2017-12-19 2019-06-27 Biological Dynamics, Inc. Methods and devices for detection of multiple analytes from a biological sample
WO2020223900A1 (en) * 2019-05-07 2020-11-12 Boe Technology Group Co., Ltd. Method of classifying and counting cells in a sample, bioassay kit, and micropore array plate
WO2025083614A1 (en) * 2023-10-19 2025-04-24 Vital Biosciences Inc. Devices, systems, and methods for optical analysis of biological samples

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WO1998022819A1 (de) * 1996-11-16 1998-05-28 Nmi Naturwissenschaftliches Und Medizinisches Institut An Der Universität Tübingen In Reutlingen Stiftung Bürgerlichen Rechts Mikroelementenanordnung, verfahren zum kontaktieren von in einer flüssigen umgebung befindlichen zellen und verfahren zum herstellen einer mikroelementenanordnung
US5922604A (en) * 1997-06-05 1999-07-13 Gene Tec Corporation Thin reaction chambers for containing and handling liquid microvolumes
FR2787582B1 (fr) * 1998-12-16 2001-01-12 Commissariat Energie Atomique Procede de fabrication d'une biopuce et biopuce
US20060068409A1 (en) * 2000-11-27 2006-03-30 Phan Brigitte C Use of restriction enzymes and other chemical methods to decrease non-specific binding in dual bead assays and related bio-discs, methods, and system apparatus for detecting medical targets
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