GB2561173A - Microfluidic device for detection of analytes - Google Patents
Microfluidic device for detection of analytes Download PDFInfo
- Publication number
- GB2561173A GB2561173A GB1705328.1A GB201705328A GB2561173A GB 2561173 A GB2561173 A GB 2561173A GB 201705328 A GB201705328 A GB 201705328A GB 2561173 A GB2561173 A GB 2561173A
- Authority
- GB
- United Kingdom
- Prior art keywords
- microfluidic device
- analyte
- chambers
- capture
- fluid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
- G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
- G01N27/06—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
- G01N27/07—Construction of measuring vessels; Electrodes therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56961—Plant cells or fungi
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N35/00069—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0621—Control of the sequence of chambers filled or emptied
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0668—Trapping microscopic beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/088—Passive control of flow resistance by specific surface properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Dispersion Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Fluid Mechanics (AREA)
- Electrochemistry (AREA)
- Botany (AREA)
- Mycology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1705328.1A GB2561173A (en) | 2017-04-03 | 2017-04-03 | Microfluidic device for detection of analytes |
| EP18714243.5A EP3606667B1 (en) | 2017-04-03 | 2018-03-28 | Microfluidic device for detection of analytes |
| ES18714243T ES2992414T3 (es) | 2017-04-03 | 2018-03-28 | Dispositivo microfluídico para la detección de analitos |
| US16/500,190 US11406976B2 (en) | 2017-04-03 | 2018-03-28 | Microfluidic device for detection of analytes |
| PCT/EP2018/057997 WO2018184957A1 (en) | 2017-04-03 | 2018-03-28 | Microfluidic device for detection of analytes |
| PL18714243.5T PL3606667T3 (pl) | 2017-04-03 | 2018-03-28 | Urządzenie mikroprzepływowe do wykrywania analitów |
| CA3058081A CA3058081C (en) | 2017-04-03 | 2018-03-28 | MICROFLUID DEVICE FOR ANALYTE DETECTION |
| JP2019554648A JP7202664B2 (ja) | 2017-04-03 | 2018-03-28 | 分析物検出用の微少流体装置 |
| AU2018247760A AU2018247760B2 (en) | 2017-04-03 | 2018-03-28 | Microfluidic device for detection of analytes |
| US17/857,824 US11850588B2 (en) | 2017-04-03 | 2022-07-05 | Microfluidic device for detection of analytes |
| AU2022283663A AU2022283663B2 (en) | 2017-04-03 | 2022-12-06 | Microfluidic device for detection of analytes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1705328.1A GB2561173A (en) | 2017-04-03 | 2017-04-03 | Microfluidic device for detection of analytes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB201705328D0 GB201705328D0 (en) | 2017-05-17 |
| GB2561173A true GB2561173A (en) | 2018-10-10 |
Family
ID=58682739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1705328.1A Withdrawn GB2561173A (en) | 2017-04-03 | 2017-04-03 | Microfluidic device for detection of analytes |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11406976B2 (https=) |
| EP (1) | EP3606667B1 (https=) |
| JP (1) | JP7202664B2 (https=) |
| AU (2) | AU2018247760B2 (https=) |
| CA (1) | CA3058081C (https=) |
| ES (1) | ES2992414T3 (https=) |
| GB (1) | GB2561173A (https=) |
| PL (1) | PL3606667T3 (https=) |
| WO (1) | WO2018184957A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019126388A1 (en) * | 2017-12-19 | 2019-06-27 | Biological Dynamics, Inc. | Methods and devices for detection of multiple analytes from a biological sample |
| WO2020223900A1 (en) * | 2019-05-07 | 2020-11-12 | Boe Technology Group Co., Ltd. | Method of classifying and counting cells in a sample, bioassay kit, and micropore array plate |
| WO2025083614A1 (en) * | 2023-10-19 | 2025-04-24 | Vital Biosciences Inc. | Devices, systems, and methods for optical analysis of biological samples |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000036145A1 (fr) * | 1998-12-16 | 2000-06-22 | Commissariat A L'energie Atomique | Procede de fabrication d'une biopuce et biopuce |
| US6315940B1 (en) * | 1996-11-16 | 2001-11-13 | Nmi Naturwissenschaftliches Und Medizinisches Institut An Der Universitat Tubingen In Reutlingen | Microelement device |
| US20080130003A1 (en) * | 2006-12-01 | 2008-06-05 | Canon Kabushiki Kaisha | Chemical sensing apparatus and chemical sensing method |
| WO2014206968A1 (en) * | 2013-06-24 | 2014-12-31 | Dublin City University | An aperture array substrate device, a detection system and a method for detecting analytes in a sample |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5922604A (en) * | 1997-06-05 | 1999-07-13 | Gene Tec Corporation | Thin reaction chambers for containing and handling liquid microvolumes |
| US20060068409A1 (en) * | 2000-11-27 | 2006-03-30 | Phan Brigitte C | Use of restriction enzymes and other chemical methods to decrease non-specific binding in dual bead assays and related bio-discs, methods, and system apparatus for detecting medical targets |
| JP2005530127A (ja) * | 2001-11-27 | 2005-10-06 | バースタイン テクノロジーズ,インコーポレイティド | 光磁気バイオディスクおよび関連の方法を含むシステム |
| GB0311902D0 (en) * | 2003-05-22 | 2003-06-25 | Cambridge Life Sciences | Assay method and apparatus |
| US7731907B2 (en) * | 2005-04-09 | 2010-06-08 | Boehringer Ingelheim Microparts Gmbh | Device and process for testing a sample liquid |
| WO2006118420A1 (en) * | 2005-04-30 | 2006-11-09 | Jae Chern Yoo | Bio-disc, bio-driver apparatus, and assay method using the same |
| JP5030110B2 (ja) * | 2005-12-21 | 2012-09-19 | サムスン エレクトロニクス カンパニー リミテッド | バイオメモリディスクドライブ装置及びそれを用いた分析方法 |
| JP2008157923A (ja) * | 2006-12-01 | 2008-07-10 | Canon Inc | 化学センシング装置及び化学センシング方法 |
| KR100913148B1 (ko) * | 2007-04-10 | 2009-08-19 | 이금필 | 자성입자를 포함하는 자기력 기반 바이오 센서 |
| KR101335726B1 (ko) * | 2007-06-04 | 2013-12-04 | 삼성전자주식회사 | 면역혈청 검사 및 생화학 검사를 동시에 수행하는 디스크형미세유동장치 |
| WO2009029073A1 (en) * | 2007-08-30 | 2009-03-05 | The Trustees Of Tufts College | Methods for determining the concentration of an analyte in solution. |
| US20110192726A1 (en) * | 2008-10-31 | 2011-08-11 | Agency For Science ,Technology And Research | Device and method for detection of analyte from a sample |
| JP2011232328A (ja) * | 2010-04-09 | 2011-11-17 | Hitachi Ltd | 生体物質検出アレイ、計測装置および計測方法 |
| AU2013212574C1 (en) * | 2012-01-27 | 2017-03-30 | University Of Tennessee Research Foundation | Method and apparatus for detection of a biomarker by alternating current electrokinetics |
| JP2013220066A (ja) * | 2012-04-17 | 2013-10-28 | Hitachi Ltd | センサチップ及びそれを用いた測定方法 |
| WO2015187792A1 (en) * | 2014-06-05 | 2015-12-10 | President And Fellows Of Harvard College | Protein analysis assay system |
| US10274492B2 (en) * | 2015-04-10 | 2019-04-30 | The Curators Of The University Of Missouri | High sensitivity impedance sensor |
| WO2017027384A1 (en) | 2015-08-07 | 2017-02-16 | Poc Medical Systems, Inc. | Microfluidic devices and methods of use thereof |
| US20170010259A1 (en) * | 2016-06-12 | 2017-01-12 | Ghassem Amoabediny | Multiplexed microfluidic proteomic platform |
-
2017
- 2017-04-03 GB GB1705328.1A patent/GB2561173A/en not_active Withdrawn
-
2018
- 2018-03-28 AU AU2018247760A patent/AU2018247760B2/en active Active
- 2018-03-28 EP EP18714243.5A patent/EP3606667B1/en active Active
- 2018-03-28 WO PCT/EP2018/057997 patent/WO2018184957A1/en not_active Ceased
- 2018-03-28 US US16/500,190 patent/US11406976B2/en active Active
- 2018-03-28 CA CA3058081A patent/CA3058081C/en active Active
- 2018-03-28 JP JP2019554648A patent/JP7202664B2/ja active Active
- 2018-03-28 ES ES18714243T patent/ES2992414T3/es active Active
- 2018-03-28 PL PL18714243.5T patent/PL3606667T3/pl unknown
-
2022
- 2022-07-05 US US17/857,824 patent/US11850588B2/en active Active
- 2022-12-06 AU AU2022283663A patent/AU2022283663B2/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6315940B1 (en) * | 1996-11-16 | 2001-11-13 | Nmi Naturwissenschaftliches Und Medizinisches Institut An Der Universitat Tubingen In Reutlingen | Microelement device |
| WO2000036145A1 (fr) * | 1998-12-16 | 2000-06-22 | Commissariat A L'energie Atomique | Procede de fabrication d'une biopuce et biopuce |
| US20080130003A1 (en) * | 2006-12-01 | 2008-06-05 | Canon Kabushiki Kaisha | Chemical sensing apparatus and chemical sensing method |
| WO2014206968A1 (en) * | 2013-06-24 | 2014-12-31 | Dublin City University | An aperture array substrate device, a detection system and a method for detecting analytes in a sample |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018247760A1 (en) | 2019-11-07 |
| EP3606667C0 (en) | 2024-11-06 |
| JP7202664B2 (ja) | 2023-01-12 |
| AU2022283663B2 (en) | 2024-06-13 |
| US20210106991A1 (en) | 2021-04-15 |
| CA3058081A1 (en) | 2018-10-11 |
| EP3606667A1 (en) | 2020-02-12 |
| AU2022283663A1 (en) | 2023-02-02 |
| JP2020515864A (ja) | 2020-05-28 |
| CA3058081C (en) | 2024-10-01 |
| US11850588B2 (en) | 2023-12-26 |
| GB201705328D0 (en) | 2017-05-17 |
| EP3606667B1 (en) | 2024-11-06 |
| WO2018184957A1 (en) | 2018-10-11 |
| PL3606667T3 (pl) | 2025-03-17 |
| AU2018247760B2 (en) | 2022-09-08 |
| US20230037522A1 (en) | 2023-02-09 |
| US11406976B2 (en) | 2022-08-09 |
| ES2992414T3 (es) | 2024-12-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2022283663B2 (en) | Microfluidic device for detection of analytes | |
| US20240110248A1 (en) | Extract from a body fluid comprising a micro rna | |
| US8940663B2 (en) | Nano-scale biosensors | |
| Lei et al. | Poly (glycidyl methacrylate-co-2-hydroxyethyl methacrylate) brushes as peptide/protein microarray substrate for improving protein binding and functionality | |
| US11391673B2 (en) | Method for preparing encoded hydrogel particles, and encoded hydrogel particles prepared thereby | |
| Kim et al. | Highly sensitive three-dimensional interdigitated microelectrode biosensors embedded with porosity tunable hydrogel for detecting proteins | |
| Zhao et al. | Shape-coded hydrogel microparticles integrated with hybridization chain reaction and a microfluidic chip for sensitive detection of multi-target miRNAs | |
| Srinivas et al. | Oil-isolated hydrogel microstructures for sensitive bioassays on-chip | |
| Gao et al. | Reliable breast cancer miRNAs detection with enhanced silicon nanowire biosensor by PNA probe and optical calibration | |
| US10570461B2 (en) | Methods of detecting tumor cells | |
| JP2024513691A (ja) | バイオアッセイ感度を増強するための微小流体微粒子標識インピーダンスセンサーアレイ | |
| Yao et al. | Hydrogel-Based Microdroplet Ensembles Encapsulating Multiplexed EXPAR Assays for Trichromic Digital Profiling of MicroRNAs and in-Depth Classification of Primary Urethral Cancers | |
| Kumar et al. | Ultrasensitive melanoma biomarker detection using a microchip SERS immunoassay with anisotropic Au–Ag alloy nanoboxes | |
| Xu et al. | Recent development on nanomaterial‐based biosensors for identifying thyroid tumor biomarkers | |
| Thiele et al. | StarPEG–heparin biosensors for rapid and portable diagnostics in complex biofluids | |
| EP4592379A1 (en) | Method for forming microdroplets | |
| Kim et al. | On-chip plasmonic immunoassay based on targeted assembly of gold nanoplasmonic particles | |
| US20190154679A1 (en) | Apparatuses and methods for cell and tissue assays and agent delivery | |
| Zhu et al. | PEG-based autonomous capillary system with integrated microbead array for immunoassay | |
| Bahari et al. | Label-free biosensing of microRNA-423-5p in saliva sample of patients using KAUST catalysis center-1 modified dendritic AuNPs: a new platform towards early-stage diagnosis of oral cancer | |
| US20250383348A1 (en) | Sessile drop biosensor and extracellular vesicle detection method using same | |
| Shapiro | Rational hydrogel design for point-of-care bioassays | |
| Cohen | Single Molecule Detection of Blood Biomarkers for Disease Diagnostics | |
| Zhang et al. | Investigation of plasmonic enhanced fluorescence effect induced from chips possessing numerous hotspots prepared by a facile process: Applied for the recognition of antigen-antibody reaction | |
| Peng et al. | Silicon Micropillar-Enhanced CRISPR Biosensor for Rapid and Sensitive Detection of Drug-Resistant Bacteria |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |