CA3056855A1 - A breath-condensate analyser - Google Patents

A breath-condensate analyser Download PDF

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Publication number
CA3056855A1
CA3056855A1 CA3056855A CA3056855A CA3056855A1 CA 3056855 A1 CA3056855 A1 CA 3056855A1 CA 3056855 A CA3056855 A CA 3056855A CA 3056855 A CA3056855 A CA 3056855A CA 3056855 A1 CA3056855 A1 CA 3056855A1
Authority
CA
Canada
Prior art keywords
housing
analyser
cartridge
breath
analyser according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3056855A
Other languages
English (en)
French (fr)
Inventor
Helle FUNCH-NIELSEN
Original Assignee
Exhalation Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exhalation Technology Ltd filed Critical Exhalation Technology Ltd
Publication of CA3056855A1 publication Critical patent/CA3056855A1/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/497Physical analysis of biological material of gaseous biological material, e.g. breath
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/01Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/082Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/087Measuring breath flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/097Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B2010/0083Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements for taking gas samples
    • A61B2010/0087Breath samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/4022Concentrating samples by thermal techniques; Phase changes
    • G01N2001/4033Concentrating samples by thermal techniques; Phase changes sample concentrated on a cold spot, e.g. condensation or distillation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00Indexing codes associated with group G01N29/00
    • G01N2291/02Indexing codes associated with the analysed material
    • G01N2291/025Change of phase or condition
    • G01N2291/0253Condensation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N25/00Investigating or analyzing materials by the use of thermal means
    • G01N25/14Investigating or analyzing materials by the use of thermal means by using distillation, extraction, sublimation, condensation, freezing, or crystallisation
    • G01N25/142Investigating or analyzing materials by the use of thermal means by using distillation, extraction, sublimation, condensation, freezing, or crystallisation by condensation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CA3056855A 2017-03-20 2018-03-20 A breath-condensate analyser Pending CA3056855A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1704367.0A GB201704367D0 (en) 2017-03-20 2017-03-20 A breath condensate analyser
GB1704367.0 2017-03-20
PCT/GB2018/050720 WO2018172760A1 (en) 2017-03-20 2018-03-20 A breath-condensate analyser

Publications (1)

Publication Number Publication Date
CA3056855A1 true CA3056855A1 (en) 2018-09-27

Family

ID=58688399

Family Applications (2)

Application Number Title Priority Date Filing Date
CA3056855A Pending CA3056855A1 (en) 2017-03-20 2018-03-20 A breath-condensate analyser
CA3056858A Pending CA3056858A1 (en) 2017-03-20 2018-03-20 A breath-condensate device

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA3056858A Pending CA3056858A1 (en) 2017-03-20 2018-03-20 A breath-condensate device

Country Status (13)

Country Link
US (2) US11885794B2 (https=)
EP (2) EP3602043B1 (https=)
JP (2) JP7261172B2 (https=)
KR (2) KR102490939B1 (https=)
CN (2) CN110431420A (https=)
AU (2) AU2018238862B2 (https=)
CA (2) CA3056855A1 (https=)
DK (1) DK3602042T3 (https=)
ES (2) ES3007612T3 (https=)
FI (1) FI3602042T3 (https=)
GB (1) GB201704367D0 (https=)
PL (1) PL3602043T3 (https=)
WO (2) WO2018172760A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020254819A1 (en) * 2019-06-19 2020-12-24 Exhalation Technology Limited A collection device for exhaled breath

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108459044A (zh) * 2018-05-23 2018-08-28 无锡森威尔化工装备科技有限公司 一种黑木测试设备
CN114040708A (zh) * 2019-06-25 2022-02-11 新加坡国立大学 呼吸采样装置
CN110368039B (zh) * 2019-08-12 2024-02-20 北京大学第一医院 一种呼出气冷凝液收集器
CN117883121A (zh) 2019-08-26 2024-04-16 泽特奥科技公司 利用呼出气诊断结核病和其他疾病
GB201916214D0 (en) * 2019-11-07 2019-12-25 Chen Yu Chih Exhaled breath collection device
AU2021226138A1 (en) * 2020-02-28 2022-10-20 Breathe BioMedical Inc. Apparatus and method for controlling a flow of breath to a sorbent tube
WO2021211821A2 (en) * 2020-04-15 2021-10-21 The Regents Of The University Of California Sample collection methods and apparatus for viral load level diagnosis
US12442726B2 (en) 2020-04-19 2025-10-14 John J. Daniels Mask-based testing system for detecting biomarkers in exhaled breath condensate, aerosols and gases
US12369816B2 (en) 2020-04-19 2025-07-29 John J. Daniels Mask-based diagnostic system using exhaled breath condensate
US12533047B2 (en) 2020-04-19 2026-01-27 John J. Daniels Mask-based diagnostic system using exhaled breath condensate
US12031982B2 (en) * 2020-04-19 2024-07-09 John J. Daniels Using exhaled breath condensate for testing for a biomarker of COVID-19
CN111436974A (zh) * 2020-05-12 2020-07-24 江苏一米生物科技有限公司 收集呼吸道气体的装置及其方法
GB202011756D0 (en) * 2020-07-29 2020-09-09 Exhalation Tech Limited A modular mouthpiece
EP4362784A4 (en) 2021-01-13 2025-04-09 3M Innovative Properties Company Devices and methods for collecting and analyzing bio-aerosol samples
CN112932459B (zh) * 2021-01-29 2025-01-28 西安交通大学第二附属医院 一种用于呼吸疾病检测的无创分析装置及其系统
US20220386893A1 (en) * 2021-03-31 2022-12-08 Zeteo Tech Inc. Capturing truncated proteoforms in exhaled breath for diagnosis and treatment of diseases
EP4312749A4 (en) 2021-03-31 2025-07-09 Zeteo Tech Inc DIAGNOSIS OF RESPIRATORY DISEASES BY CAPTURE OF AEROSOLIZED BIOMATERIAL PARTICLES USING FIXED BED SYSTEMS AND METHODS
KR20230164096A (ko) * 2021-04-02 2023-12-01 쓰리엠 이노베이티브 프로퍼티즈 캄파니 샘플 수집 장치 및 방법
CN112940927B (zh) * 2021-04-12 2025-01-28 天津大学 一种对空气结核杆菌检测的系统
WO2022248936A2 (en) * 2021-05-28 2022-12-01 Exhalation Technology Ltd Device and method for detecting a component of exhaled breath condensate
PL249479B1 (pl) * 2021-07-20 2026-04-27 Gdański Uniwersytet Medyczny Sposób pobierania próbki oddechu i sposób analizy próbki materiału biologicznego pod kątem wykrywania obecności stanu chorobowego pacjenta
WO2023153958A2 (ru) * 2022-02-08 2023-08-17 Федеральное Государственное Бюджетное Учреждение Науки Институт Синтетических Полимерных Материалов Имени Н.С. Ениколопова Российской Академии Наук (Испм Ран) Способ ранней неинвазивной диагностики covid-19 путем анализа выдыхаемого человеком воздуха

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6033368A (en) 1996-03-28 2000-03-07 Nitromed, Inc. Condensate colorimetric nitrogen oxide analyzer
JP4452783B2 (ja) 1999-10-07 2010-04-21 学校法人日本大学 呼気分析装置を用いた肝硬変検査方法及び装置
DE19951204C2 (de) 1999-10-15 2002-08-08 Filt Forschungsgesellschaft Fu Verfahren zur Analyse der Inhaltsstoffe der Ausatemluft
DE10137565B4 (de) 2001-07-30 2004-07-15 Filt Lungen- Und Thoraxdiagnostik Gmbh Verfahren zur Bestimmung von Parametern eines Atemkondensats
US7948041B2 (en) * 2005-05-19 2011-05-24 Nanomix, Inc. Sensor having a thin-film inhibition layer
JP2004361160A (ja) * 2003-06-03 2004-12-24 Terametsukusu Kk 呼気凝縮液採取装置
US20050130226A1 (en) 2003-09-26 2005-06-16 The University Of Cincinnati Fully integrated protein lab-on-a-chip with smart microfluidics for spot array generation
WO2007001342A2 (en) 2004-08-20 2007-01-04 University Of Virginia Patent Foundation Exhaled breath condensate collection and assay system and method
DE102005020102B3 (de) * 2005-04-25 2006-11-30 Universität Potsdam Verfahren und Vorrichtung zur Gewinnung und Analyse von Atemkondensaten
US8002712B2 (en) 2006-01-26 2011-08-23 Meka Vikas V Breath and breath condensate analysis system and associated methods
US7914460B2 (en) * 2006-08-15 2011-03-29 University Of Florida Research Foundation, Inc. Condensate glucose analyzer
WO2008022183A1 (en) 2006-08-15 2008-02-21 University Of Florida Research Foundation, Inc. Condensate glucose analyzer
GB2441781B (en) * 2006-09-13 2010-05-19 Autoliv Dev Breath analyser
GB2451249A (en) 2007-07-24 2009-01-28 Equine Healthcare Ltd A breath condensate collector
CN101238980A (zh) * 2008-03-14 2008-08-13 吉林大学 呼出气冷凝液(ebc)收集装置
US8821409B2 (en) 2008-12-23 2014-09-02 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Lung aerosol collection device
US8394030B2 (en) * 2009-03-18 2013-03-12 Carefusion 207, Inc. Exhaled breath condensate biometric marker measurement apparatus and method
US9357946B2 (en) 2009-04-15 2016-06-07 Nanomix, Inc. Breath condensate sampler and detector and breath/breath condensate sampler and detector
EA023922B1 (ru) * 2009-09-09 2016-07-29 Сенса Буэс Аб Обнаружение лекарственного средства в выдыхаемом воздухе
US9763600B2 (en) 2010-02-17 2017-09-19 Koninklijke Philips N.V. Nitric oxide measurement method and apparatus
CN104939831B (zh) * 2010-09-09 2018-11-09 森撒部伊斯公司 从受试者的呼出气中收集样本的系统和方法及其用途
EP2518499B1 (en) * 2011-03-09 2015-06-10 Sensa Bues AB A portable sampling device and method for drug detection from exhaled breath
GB201313817D0 (en) 2013-08-01 2013-09-18 Maddison Product Design Ltd Exhaled breath condensate collector
SG10201703241UA (en) 2013-08-30 2017-06-29 Capnia Inc Universal breath analysis sampling device
KR20160050048A (ko) 2013-08-30 2016-05-10 카프니아, 인코포레이티드 주상 흐름 가스 샘플링 및 측정 시스템
CN106999098B (zh) 2014-11-19 2021-06-29 皇家飞利浦有限公司 用于确定对象的健康的方法和设备
DE102015203719A1 (de) * 2015-03-03 2016-09-08 Robert Bosch Gmbh Vorrichtung und Verfahren zur Atemgasanalyse und Atemgasanalysegerät
CN104958073A (zh) * 2015-07-03 2015-10-07 深圳市共进电子股份有限公司 潮气传感器、电子设备、呼吸检测系统和方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020254819A1 (en) * 2019-06-19 2020-12-24 Exhalation Technology Limited A collection device for exhaled breath
US12239430B2 (en) 2019-06-19 2025-03-04 Exhalation Technology Limited Collection device for exhaled breath
AU2020296340B2 (en) * 2019-06-19 2025-12-04 Exhalation Technology Limited A collection device for exhaled breath

Also Published As

Publication number Publication date
WO2018172760A1 (en) 2018-09-27
DK3602042T3 (da) 2023-03-06
JP7517823B2 (ja) 2024-07-17
AU2018238863A1 (en) 2019-10-31
CN110431419B (zh) 2021-10-26
US11733231B2 (en) 2023-08-22
KR20190128682A (ko) 2019-11-18
JP2020514767A (ja) 2020-05-21
AU2018238862B2 (en) 2024-10-24
EP3602043A1 (en) 2020-02-05
PL3602043T3 (pl) 2025-02-24
CA3056858A1 (en) 2018-09-27
AU2018238862A1 (en) 2019-10-31
WO2018172761A1 (en) 2018-09-27
ES3007612T3 (en) 2025-03-20
EP3602043B1 (en) 2024-12-11
JP7261172B2 (ja) 2023-04-19
AU2018238863B2 (en) 2024-10-24
EP3602043C0 (en) 2024-12-11
GB201704367D0 (en) 2017-05-03
US11885794B2 (en) 2024-01-30
ES2940098T3 (es) 2023-05-03
JP2020511667A (ja) 2020-04-16
CN110431419A (zh) 2019-11-08
CN110431420A (zh) 2019-11-08
EP3602042B1 (en) 2022-12-14
EP3602042A1 (en) 2020-02-05
FI3602042T3 (fi) 2023-03-20
KR20190128693A (ko) 2019-11-18
KR102490939B1 (ko) 2023-01-25
US20200033323A1 (en) 2020-01-30
US20200041485A1 (en) 2020-02-06

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