JP2020511667A - 呼吸凝縮物デバイス - Google Patents
呼吸凝縮物デバイス Download PDFInfo
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- JP2020511667A JP2020511667A JP2019552630A JP2019552630A JP2020511667A JP 2020511667 A JP2020511667 A JP 2020511667A JP 2019552630 A JP2019552630 A JP 2019552630A JP 2019552630 A JP2019552630 A JP 2019552630A JP 2020511667 A JP2020511667 A JP 2020511667A
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- XOGGUFAVLNCTRS-UHFFFAOYSA-N tetrapotassium;iron(2+);hexacyanide Chemical compound [K+].[K+].[K+].[K+].[Fe+2].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] XOGGUFAVLNCTRS-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/087—Measuring breath flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B2010/0083—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements for taking gas samples
- A61B2010/0087—Breath samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4022—Concentrating samples by thermal techniques; Phase changes
- G01N2001/4033—Concentrating samples by thermal techniques; Phase changes sample concentrated on a cold spot, e.g. condensation or distillation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2291/00—Indexing codes associated with group G01N29/00
- G01N2291/02—Indexing codes associated with the analysed material
- G01N2291/025—Change of phase or condition
- G01N2291/0253—Condensation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N25/00—Investigating or analyzing materials by the use of thermal means
- G01N25/14—Investigating or analyzing materials by the use of thermal means by using distillation, extraction, sublimation, condensation, freezing, or crystallisation
- G01N25/142—Investigating or analyzing materials by the use of thermal means by using distillation, extraction, sublimation, condensation, freezing, or crystallisation by condensation
Abstract
Description
Claims (23)
- 呼吸凝縮物を収集して分析するカートリッジデバイスであって、対象者からの呼気を凝縮させる凝縮ゾーンを備え、前記凝縮ゾーンが、冷却手段に対して動作可能に接続可能であり、前記デバイスが、被分析物の検出および被分析物の測定を行う1つまたは複数の別の離散領域を含み、前記カートリッジデバイスが、前記凝縮ゾーンを前記1つまたは複数の離散領域に接続する流体経路をさらに備えた、カートリッジデバイス。
- 前記凝縮ゾーンが、該凝縮ゾーンを少なくとも部分的に覆う蓋を有する、請求項1に記載のカートリッジデバイス。
- 凝縮物の有無を検出する分析開始手段を備えた、請求項1または2に記載のカートリッジデバイス。
- 前記1つまたは複数の離散領域が、測定結果の計算の基準となり得る特定の容積を有する、請求項1から3のいずれか一項に記載のカートリッジデバイス。
- 前記特定の容積が、最大4μlである、請求項4に記載のカートリッジデバイス。
- 1つまたは複数の離散領域が、1回の呼気の凝縮物の体積よりも容積が小さい被分析物検出ゾーンが存在するように、特定の容積を有する、請求項1から5のいずれか一項に記載のカートリッジデバイス。
- 離散領域の表面が、表面被膜を含み、該被膜が、前記凝縮物を取り込んで組成を決定する試薬を含む、請求項1から6のいずれか一項に記載のカートリッジデバイス。
- 前記表面被膜が、1μm〜15μmの範囲の厚さを有する、請求項7に記載のカートリッジデバイス。
- 離散領域が、凝縮ゾーンと動作可能に接続された2つ以上の電極を含み、該電極が、異なる電位に保持された、請求項1から8のいずれか一項に記載のカートリッジデバイス。
- 前記一対の電極間の電位が、可変である、請求項9に記載のカートリッジデバイス。
- さらに離散した準備領域において、試薬が前記凝縮物に添加される、請求項1から10のいずれか一項に記載のカートリッジデバイス。
- 1つまたは複数の領域の温度が制御される、請求項1から11のいずれか一項に記載のカートリッジデバイス。
- 前記凝縮物の分析用の前記試薬が、前記凝縮物サンプルが前記凝縮ゾーンから検出ゾーンまで通過する間、前記凝縮物サンプルに装填される、請求項1から12のいずれか一項に記載のカートリッジデバイス。
- 離散領域が、2〜10mmの範囲の外周を有する、請求項1から13のいずれか一項に記載のカートリッジデバイス。
- 離散領域が、5mmの外周を有する、請求項14に記載のカートリッジデバイス。
- 離散領域が、75〜750μmの高さを有する、請求項1から15のいずれか一項に記載のカートリッジデバイス。
- 離散領域が、100μmの高さを有する、請求項16に記載のカートリッジデバイス。
- 離散領域が、チャンバを備え、該チャンバが、5つの面が囲まれ、流体の進入および置換空気の退出のために第6の面が開放された、請求項1から17のいずれか一項に記載のカートリッジデバイス。
- 前記凝縮物が、膜を形成する、請求項1から18のいずれか一項に記載のカートリッジデバイス。
- ケーブル、Wi−Fi接続等の送信手段を備えた、請求項1から19のいずれか一項に記載のカートリッジデバイス。
- 決定値に対する任意の干渉が測定され、最終信号において考慮される、請求項1から20のいずれか一項に記載のカートリッジデバイス。
- 前記凝縮ゾーンへの電力が、呼気の流量または呼気の凝縮率および呼気の総収集体積を計算し得るように決定される、請求項1から21のいずれか一項に記載のカートリッジデバイス。
- 空気が該デバイスから退出し得る孔またはチャネルをさらに備え、該孔またはチャネルが、離散領域を大気と接続する、請求項1から22のいずれか一項に記載のカートリッジデバイス。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1704367.0 | 2017-03-20 | ||
GBGB1704367.0A GB201704367D0 (en) | 2017-03-20 | 2017-03-20 | A breath condensate analyser |
PCT/GB2018/050721 WO2018172761A1 (en) | 2017-03-20 | 2018-03-20 | A breath-condensate device |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2020511667A true JP2020511667A (ja) | 2020-04-16 |
JP2020511667A5 JP2020511667A5 (ja) | 2021-04-15 |
Family
ID=58688399
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019552630A Pending JP2020511667A (ja) | 2017-03-20 | 2018-03-20 | 呼吸凝縮物デバイス |
JP2019552495A Active JP7261172B2 (ja) | 2017-03-20 | 2018-03-20 | 呼気凝縮物分析装置 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019552495A Active JP7261172B2 (ja) | 2017-03-20 | 2018-03-20 | 呼気凝縮物分析装置 |
Country Status (12)
Country | Link |
---|---|
US (2) | US11885794B2 (ja) |
EP (2) | EP3602043A1 (ja) |
JP (2) | JP2020511667A (ja) |
KR (2) | KR20190128693A (ja) |
CN (2) | CN110431419B (ja) |
AU (2) | AU2018238863A1 (ja) |
CA (2) | CA3056858A1 (ja) |
DK (1) | DK3602042T3 (ja) |
ES (1) | ES2940098T3 (ja) |
FI (1) | FI3602042T3 (ja) |
GB (1) | GB201704367D0 (ja) |
WO (2) | WO2018172760A1 (ja) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108459044A (zh) * | 2018-05-23 | 2018-08-28 | 无锡森威尔化工装备科技有限公司 | 一种黑木测试设备 |
GB201908784D0 (en) * | 2019-06-19 | 2019-07-31 | Exhalation Tech Limited | A collection device for exhaled breath |
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EP3602043A1 (en) | 2020-02-05 |
CA3056855A1 (en) | 2018-09-27 |
KR20190128693A (ko) | 2019-11-18 |
EP3602042B1 (en) | 2022-12-14 |
CN110431420A (zh) | 2019-11-08 |
DK3602042T3 (da) | 2023-03-06 |
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