JP2020514767A - 呼吸凝縮物分析装置 - Google Patents
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/087—Measuring breath flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B2010/0083—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements for taking gas samples
- A61B2010/0087—Breath samples
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4022—Concentrating samples by thermal techniques; Phase changes
- G01N2001/4033—Concentrating samples by thermal techniques; Phase changes sample concentrated on a cold spot, e.g. condensation or distillation
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2291/00—Indexing codes associated with group G01N29/00
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- G—PHYSICS
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- G01N25/00—Investigating or analyzing materials by the use of thermal means
- G01N25/14—Investigating or analyzing materials by the use of thermal means by using distillation, extraction, sublimation, condensation, freezing, or crystallisation
- G01N25/142—Investigating or analyzing materials by the use of thermal means by using distillation, extraction, sublimation, condensation, freezing, or crystallisation by condensation
Abstract
Description
Claims (23)
- 呼吸凝縮物を収集して分析する分析装置であって、ハウジングを備え、該ハウジングが、冷却手段を有するとともに、対象者からの呼気を凝縮させる凝縮ゾーンを備えたカートリッジデバイスを保持し、前記冷却手段が、前記凝縮ゾーンと冷却関係にあり、前記デバイスが、被分析物の検出および被分析物の測定を行う1つまたは複数の別の離散領域を含み、前記カートリッジデバイスが、前記凝縮ゾーンを前記1つまたは複数の離散領域に接続する流体経路をさらに備え、前記ハウジングが、ユーザが内部に息を吹き込める入口ポートを有するマウスピースを含み、該マウスピースが、進入する呼吸を前記凝縮ゾーンに案内する1つまたは複数の流体通路を備えた、分析装置。
- 前記カートリッジデバイスが、前記ハウジングに対して取り外し可能に取り付け可能である、請求項1に記載の分析装置。
- 前記ハウジングが、それ自体が前記カートリッジの一部を構成する反応ゾーンを加熱する加熱手段を備えた、請求項1または2に記載の分析装置。
- 前記加熱手段が、前記ハウジング中に配置されるか、または、前記カートリッジの一部として配置された、請求項3に記載の分析装置。
- 前記ハウジングと前記カートリッジとの間に電気的接続が存在する、請求項4に記載の分析装置。
- 前記ハウジングが、唾液エアロゾルを蒸気サンプルから除去する一連のバッフルを備えた、請求項1から5のいずれか一項に記載の分析装置。
- 1つまたは複数のバッフルが前記カートリッジに設けられた、請求項6に記載の分析装置。
- 単一のバッフルが前記ハウジングおよび前記カートリッジのそれぞれに設けられた、請求項7に記載の分析装置。
- 前記ハウジングが、前記複雑なデバイスを通る少なくとも2つの流路を提供する弁機構を備えた、請求項1から8のいずれか一項に記載の分析装置。
- 前記ハウジングおよび/または前記カートリッジが、呼吸流量を測定する流量センサを備えた、請求項1から9のいずれか一項に記載の分析装置。
- 前記ハウジングおよび/または前記カートリッジが、二酸化炭素センサを備えた、請求項1から10のいずれか一項に記載の分析装置。
- 前記ハウジングおよび/または前記カートリッジが、1つまたは複数の湿度センサを備えた、請求項1から11のいずれか一項に記載の分析装置。
- 前記ハウジングおよび/または前記カートリッジが、呼気または吸気時の呼吸圧を測定する圧力センサを備えた、請求項1から12のいずれか一項に記載の分析装置。
- 前記ハウジングおよび/または前記カートリッジが、呼吸温度を測定する温度センサを備えた、請求項1から13のいずれか一項に記載の分析装置。
- 前記ハウジングが、1つもしくは複数のセンサからの情報の外部装置への提供ならびに/または外部源からの電気エネルギーの受電を行う電子インターフェースを備えた、請求項1から14のいずれか一項に記載の分析装置。
- 前記ハウジングが、データ処理ユニットを備えた、請求項1から15のいずれか一項に記載の分析装置。
- 前記ハウジングが、情報またはデータを外部装置に送信する送達手段を備えた、請求項1から16のいずれか一項に記載の分析装置。
- 前記ハウジングが、データ格納手段を備えた、請求項1から17のいずれか一項に記載の分析装置。
- 前記ハウジングが、取り外し可能なデータ格納手段に対する電子インターフェースを備えた、請求項1から18のいずれか一項に記載の分析装置。
- 前記ハウジングが、音声出力を備えた、請求項1から19のいずれか一項に記載の分析装置。
- マウスピースを備え、該マウスピースが、入口ポートおよび出口弁を備え、複数のチャンバが間に介在して、前記入口ポートから前記出口弁まで流体流を案内し、前記チャンバが、流体流の方向を90°変化させるように構成された、請求項1から20のいずれか一項に記載の分析装置。
- 少なくとも2つチャンバが一方向弁により分離された、請求項21に記載の分析装置。
- 呼吸凝縮物分析装置に用いられるマウスピースであって、マウスピース本体を備え、入口ポートおよび出口弁を有し、複数のチャンバが間に介在して、前記入口ポートから前記出口弁まで流体流を案内し、前記チャンバが、流体流の方向を90°変化させるように構成された、マウスピース。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1704367.0A GB201704367D0 (en) | 2017-03-20 | 2017-03-20 | A breath condensate analyser |
GB1704367.0 | 2017-03-20 | ||
PCT/GB2018/050720 WO2018172760A1 (en) | 2017-03-20 | 2018-03-20 | A breath-condensate analyser |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2020514767A true JP2020514767A (ja) | 2020-05-21 |
JP2020514767A5 JP2020514767A5 (ja) | 2021-04-15 |
JP7261172B2 JP7261172B2 (ja) | 2023-04-19 |
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019552630A Pending JP2020511667A (ja) | 2017-03-20 | 2018-03-20 | 呼吸凝縮物デバイス |
JP2019552495A Active JP7261172B2 (ja) | 2017-03-20 | 2018-03-20 | 呼気凝縮物分析装置 |
Family Applications Before (1)
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JP2019552630A Pending JP2020511667A (ja) | 2017-03-20 | 2018-03-20 | 呼吸凝縮物デバイス |
Country Status (12)
Country | Link |
---|---|
US (2) | US11885794B2 (ja) |
EP (2) | EP3602043A1 (ja) |
JP (2) | JP2020511667A (ja) |
KR (2) | KR102490939B1 (ja) |
CN (2) | CN110431419B (ja) |
AU (2) | AU2018238862A1 (ja) |
CA (2) | CA3056858A1 (ja) |
DK (1) | DK3602042T3 (ja) |
ES (1) | ES2940098T3 (ja) |
FI (1) | FI3602042T3 (ja) |
GB (1) | GB201704367D0 (ja) |
WO (2) | WO2018172760A1 (ja) |
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CN110368039B (zh) * | 2019-08-12 | 2024-02-20 | 北京大学第一医院 | 一种呼出气冷凝液收集器 |
GB201916214D0 (en) * | 2019-11-07 | 2019-12-25 | Chen Yu Chih | Exhaled breath collection device |
WO2021211821A2 (en) * | 2020-04-15 | 2021-10-21 | The Regents Of The University Of California | Sample collection methods and apparatus for viral load level diagnosis |
US20210325381A1 (en) * | 2020-04-19 | 2021-10-21 | John J. Daniels | Using Exhaled Breath Condensate for Testing for a Biomarker of COVID-19 |
GB202011756D0 (en) * | 2020-07-29 | 2020-09-09 | Exhalation Tech Limited | A modular mouthpiece |
CN112932459A (zh) * | 2021-01-29 | 2021-06-11 | 西安交通大学第二附属医院 | 一种用于呼吸疾病检测的无创分析装置及其系统 |
WO2022248936A2 (en) * | 2021-05-28 | 2022-12-01 | Exhalation Technology Ltd | Device and method for detecting a component of exhaled breath condensate |
PL438534A1 (pl) * | 2021-07-20 | 2023-01-23 | Gdański Uniwersytet Medyczny | Aparat do pobierania kondensatu wydychanego powietrza i sposób diagnozowania stanu chorobowego pacjenta |
WO2023153958A2 (ru) * | 2022-02-08 | 2023-08-17 | Федеральное Государственное Бюджетное Учреждение Науки Институт Синтетических Полимерных Материалов Имени Н.С. Ениколопова Российской Академии Наук (Испм Ран) | Способ ранней неинвазивной диагностики covid-19 путем анализа выдыхаемого человеком воздуха |
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CA3056855A1 (en) | 2018-09-27 |
US11885794B2 (en) | 2024-01-30 |
KR20190128693A (ko) | 2019-11-18 |
CN110431420A (zh) | 2019-11-08 |
KR102490939B1 (ko) | 2023-01-25 |
WO2018172760A1 (en) | 2018-09-27 |
JP2020511667A (ja) | 2020-04-16 |
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CN110431419B (zh) | 2021-10-26 |
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ES2940098T3 (es) | 2023-05-03 |
CN110431419A (zh) | 2019-11-08 |
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CA3056858A1 (en) | 2018-09-27 |
DK3602042T3 (da) | 2023-03-06 |
US20200041485A1 (en) | 2020-02-06 |
JP7261172B2 (ja) | 2023-04-19 |
KR20190128682A (ko) | 2019-11-18 |
WO2018172761A1 (en) | 2018-09-27 |
AU2018238863A1 (en) | 2019-10-31 |
EP3602042B1 (en) | 2022-12-14 |
AU2018238862A1 (en) | 2019-10-31 |
FI3602042T3 (fi) | 2023-03-20 |
GB201704367D0 (en) | 2017-05-03 |
EP3602043A1 (en) | 2020-02-05 |
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