CA3055107A1 - Intradialytic use of sodium thiosulfate - Google Patents

Intradialytic use of sodium thiosulfate Download PDF

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Publication number
CA3055107A1
CA3055107A1 CA3055107A CA3055107A CA3055107A1 CA 3055107 A1 CA3055107 A1 CA 3055107A1 CA 3055107 A CA3055107 A CA 3055107A CA 3055107 A CA3055107 A CA 3055107A CA 3055107 A1 CA3055107 A1 CA 3055107A1
Authority
CA
Canada
Prior art keywords
thiosulfate
dialysate
subject
unspiked
micromolar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3055107A
Other languages
English (en)
French (fr)
Inventor
Craig Sherman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hope Medical Enterprises Inc
Original Assignee
Hope Medical Enterprises Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hope Medical Enterprises Inc filed Critical Hope Medical Enterprises Inc
Publication of CA3055107A1 publication Critical patent/CA3055107A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA3055107A 2017-03-08 2018-03-06 Intradialytic use of sodium thiosulfate Pending CA3055107A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762468871P 2017-03-08 2017-03-08
US62/468,871 2017-03-08
PCT/US2018/021069 WO2018165108A1 (en) 2017-03-08 2018-03-06 Intradialytic use of sodium thiosulfate

Publications (1)

Publication Number Publication Date
CA3055107A1 true CA3055107A1 (en) 2018-09-13

Family

ID=63446695

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3055107A Pending CA3055107A1 (en) 2017-03-08 2018-03-06 Intradialytic use of sodium thiosulfate

Country Status (14)

Country Link
US (5) US10744156B2 (https=)
EP (2) EP4403215A3 (https=)
JP (3) JP7416622B2 (https=)
KR (4) KR20250007674A (https=)
AR (1) AR111236A1 (https=)
AU (1) AU2018231072B2 (https=)
CA (1) CA3055107A1 (https=)
ES (1) ES2992792T3 (https=)
IL (4) IL268883B (https=)
NZ (4) NZ788158A (https=)
PH (1) PH12019501971A1 (https=)
TW (2) TWI869743B (https=)
WO (1) WO2018165108A1 (https=)
ZA (2) ZA202105781B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL268883B (en) 2017-03-08 2022-09-01 Hope Medical Entpr Inc Dba Hope Pharmaceuticals Intradialytic use of sodium thiosulfate
CN112805238A (zh) 2018-07-03 2021-05-14 芬内克制药股份有限公司 无水硫代硫酸钠和其调配物
US11850313B2 (en) * 2019-12-20 2023-12-26 The London Health Sciences Centre Research Inc. Method and compositions for protecting tissue
WO2024092228A2 (en) * 2022-10-28 2024-05-02 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Localized delivery of sodium thiosulfate nanoparticles to mitigate arterial calcification
CN116573782B (zh) * 2023-04-03 2023-11-03 迁安市宏奥工贸有限公司 脱硫废液的处理方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0218900B1 (en) 1985-09-10 1992-01-22 Research Corporation Technologies, Inc. Osmotic agents for peritoneal dialysis
US5108767A (en) * 1991-06-10 1992-04-28 Abbott Laboratories Liquid nutritional product for persons receiving renal dialysis
US6380163B1 (en) 1992-12-22 2002-04-30 Baxter International Inc. Peritoneal dialysis solutions with polypeptides
FI98538C (fi) * 1993-10-20 1997-07-10 Enso Gutzeit Oy Menetelmä natriumhydroksidin valmistamiseksi valkolipeästä
US6306836B1 (en) 1994-01-21 2001-10-23 Baxter International Inc. Peritoneal dialysis solutions containing maltodextrins and amino acids
US6436969B1 (en) 1995-09-12 2002-08-20 Kansas University Medical Center Research Institute Inc. Dialysis solutions and methods
ES2322689T3 (es) * 1999-09-22 2009-06-25 Advanced Renal Technologies Uso de un dializado con elevado contenido de citrato.
US7022315B2 (en) * 2000-04-26 2006-04-04 Oregon Health & Science University Administration of a thiol-based chemoprotectant compound
JP4882054B2 (ja) * 2000-09-13 2012-02-22 独立行政法人科学技術振興機構 腹膜透析液およびその調製法
JP5564158B2 (ja) 2003-07-09 2014-07-30 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ 亜硝酸塩によって特定の心臓血管状態を処置する方法
WO2006001345A1 (ja) 2004-06-23 2006-01-05 Kyowa Hakko Kogyo Co., Ltd. Ｌ－リジン・クエン酸塩結晶
US20070154570A1 (en) 2004-09-29 2007-07-05 Miller Christopher C Use of nitric oxide in the treatment and disinfection of biofilms
US7834065B2 (en) 2005-01-31 2010-11-16 Bmg Incorporated Medical-use two part reactive adhesive and medical-use resin having self-degradation property
US20090304600A1 (en) 2008-06-09 2009-12-10 Anupkumar Shetty Intradialytic administration of sodium thiosulfate
US8568793B2 (en) 2009-02-11 2013-10-29 Hope Medical Enterprises, Inc. Sodium nitrite-containing pharmaceutical compositions
AU2010270605B2 (en) 2009-07-08 2014-07-31 Hope Medical Enterprises, Inc. Dba Hope Pharmaceuticals Sodium thiosulfate-containing pharmaceutical compositions
CA2844759A1 (en) 2011-08-11 2013-02-14 Nathan S. Bryan Method of measuring and monitoring in vivo nitrite levels
WO2013112582A1 (en) 2012-01-23 2013-08-01 Santalis Pharmaceuticals Inc. Sandalwood oil and its uses related to clostridium infections
US9629872B2 (en) * 2012-05-10 2017-04-25 Inserm (Institut National De La Sante Et De La Recherche Medicale) Sodium thiosulphate for the treatment of ectopic calcifications
JP5486069B1 (ja) * 2012-11-05 2014-05-07 旭 酒井 透析装置
US20140350097A1 (en) 2013-05-23 2014-11-27 Medinox,Inc. Treatment of hypotension associated with hemodialysis
WO2016094409A1 (en) * 2014-12-09 2016-06-16 Villarreal Anna Methods and devices for female health monitoring
IL268883B (en) * 2017-03-08 2022-09-01 Hope Medical Entpr Inc Dba Hope Pharmaceuticals Intradialytic use of sodium thiosulfate
BR112019018861A2 (pt) 2017-03-08 2023-10-10 Hope Medical Entpr Inc Dba Hope Pharmaceuticals Uso de nitrito de sódio, método para manter os níveis fisiológicos de nitrito, prevenir enfarte do miocárdio, prevenir morte súbita cardíaca, prevenir acidente vascular cerebral, doenças cardiovasculares, pressão alta, solução aquosa

Also Published As

Publication number Publication date
ZA202209104B (en) 2024-12-18
KR20240139090A (ko) 2024-09-20
US11116790B2 (en) 2021-09-14
IL268883A (en) 2019-10-31
EP4403215A2 (en) 2024-07-24
AU2018231072B2 (en) 2024-04-04
TW201840343A (zh) 2018-11-16
US11779596B2 (en) 2023-10-10
US20240100086A1 (en) 2024-03-28
IL302827A (en) 2023-07-01
US20180256639A1 (en) 2018-09-13
NZ797803A (en) 2026-03-27
AR111236A1 (es) 2019-06-19
TW202517284A (zh) 2025-05-01
TW202315650A (zh) 2023-04-16
JP2020510680A (ja) 2020-04-09
JP7642878B2 (ja) 2025-03-10
US20250332194A1 (en) 2025-10-30
JP2025084833A (ja) 2025-06-03
KR102647836B1 (ko) 2024-03-15
IL295119B2 (en) 2023-10-01
US12370212B2 (en) 2025-07-29
AU2024203603A1 (en) 2024-06-20
KR20240038813A (ko) 2024-03-25
EP4403215A3 (en) 2024-10-09
IL268883B (en) 2022-09-01
JP2024045164A (ja) 2024-04-02
ZA202105781B (en) 2023-05-31
KR20190129911A (ko) 2019-11-20
IL302827B1 (en) 2024-06-01
NZ756704A (en) 2022-07-01
JP7416622B2 (ja) 2024-01-17
BR112019018646A2 (pt) 2020-04-07
KR102758644B1 (ko) 2025-01-23
IL295119A (en) 2022-09-01
ES2992792T3 (en) 2024-12-18
EP3592824B1 (en) 2024-06-12
PH12019501971A1 (en) 2020-06-15
EP3592824A1 (en) 2020-01-15
AU2018231072A1 (en) 2019-09-19
WO2018165108A1 (en) 2018-09-13
US10744156B2 (en) 2020-08-18
KR20250007674A (ko) 2025-01-14
NZ788158A (en) 2026-03-27
KR102706439B1 (ko) 2024-09-19
IL295119B1 (en) 2023-06-01
IL312724A (en) 2024-07-01
IL302827B2 (en) 2024-10-01
TWI869743B (zh) 2025-01-11
EP3592824A4 (en) 2020-12-23
NZ797802A (en) 2026-03-27
US20220031735A1 (en) 2022-02-03
TWI789378B (zh) 2023-01-11
US20200338120A1 (en) 2020-10-29

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