CA3051495A1 - Use of nanoparticles comprising a taxane and albumin in the treatment of hepatocellular carcinoma - Google Patents
Use of nanoparticles comprising a taxane and albumin in the treatment of hepatocellular carcinoma Download PDFInfo
- Publication number
- CA3051495A1 CA3051495A1 CA3051495A CA3051495A CA3051495A1 CA 3051495 A1 CA3051495 A1 CA 3051495A1 CA 3051495 A CA3051495 A CA 3051495A CA 3051495 A CA3051495 A CA 3051495A CA 3051495 A1 CA3051495 A1 CA 3051495A1
- Authority
- CA
- Canada
- Prior art keywords
- composition
- individual
- hcc
- nanoparticles
- taxane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Optics & Photonics (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31815310P | 2010-03-26 | 2010-03-26 | |
| US201062318153P | 2010-03-26 | 2010-03-26 | |
| US61/318153 | 2010-03-26 | ||
| CA2793536A CA2793536C (en) | 2010-03-26 | 2011-03-25 | Use of nanoparticles comprising a taxane and albumin in the treatment of hepatocellular carcinoma |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2793536A Division CA2793536C (en) | 2010-03-26 | 2011-03-25 | Use of nanoparticles comprising a taxane and albumin in the treatment of hepatocellular carcinoma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3051495A1 true CA3051495A1 (en) | 2011-09-29 |
Family
ID=44673662
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3051495A Abandoned CA3051495A1 (en) | 2010-03-26 | 2011-03-25 | Use of nanoparticles comprising a taxane and albumin in the treatment of hepatocellular carcinoma |
| CA2793536A Active CA2793536C (en) | 2010-03-26 | 2011-03-25 | Use of nanoparticles comprising a taxane and albumin in the treatment of hepatocellular carcinoma |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2793536A Active CA2793536C (en) | 2010-03-26 | 2011-03-25 | Use of nanoparticles comprising a taxane and albumin in the treatment of hepatocellular carcinoma |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US9370494B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2552438B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5847156B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101786142B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN103052385B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011230512B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112012024349A2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA3051495A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2552438T3 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2675212T3 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20160609T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE027749T2 (cg-RX-API-DMAC7.html) |
| IL (2) | IL221886A (cg-RX-API-DMAC7.html) |
| LT (1) | LT2552438T (cg-RX-API-DMAC7.html) |
| MX (2) | MX346861B (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ602382A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2552438T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2552438T (cg-RX-API-DMAC7.html) |
| TW (1) | TWI495467B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011119988A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8853260B2 (en) | 1997-06-27 | 2014-10-07 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
| JP2006524632A (ja) | 2002-12-09 | 2006-11-02 | アメリカン バイオサイエンス、インコーポレイテッド | 組成物及び薬物送達方法 |
| US8735394B2 (en) | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
| KR20070114753A (ko) | 2005-02-18 | 2007-12-04 | 아브락시스 바이오사이언스 인크. | 치료제의 조합 및 투여 방식, 및 조합 요법 |
| TR200801336T1 (tr) | 2005-08-31 | 2008-08-21 | Abraxis Bioscience, Inc. | Kararlılığı artmış zayıf su çöznurluğune sahip ilaçların preparasyonuna yönelik kompozisyonlar ve yöntemler. |
| AU2007334360B2 (en) | 2006-12-14 | 2013-10-17 | Abraxis Bioscience, Llc | Breast cancer therapy based on hormone receptor status with nanoparticles comprising taxane |
| RU2483714C2 (ru) * | 2007-03-07 | 2013-06-10 | АБРАКСИС БАЙОСАЙЕНС, ЭлЭлСи. | Наночастица, содержащая рапамицин и альбумин, в качестве противоракового агента |
| PT2155188E (pt) * | 2007-06-01 | 2013-12-19 | Abraxis Bioscience Llc | Métodos e composições para o tratamento de cancro recorrente |
| SMT201900751T1 (it) | 2009-04-15 | 2020-03-13 | Abraxis Bioscience Llc | Composizioni nanoparticellari prive di prioni e metodi |
| ES2675212T3 (es) | 2010-03-26 | 2018-07-09 | Abraxis Bioscience, Llc | Métodos de tratamiento de carcinoma hepatocelular |
| US10660965B2 (en) | 2010-03-29 | 2020-05-26 | Abraxis Bioscience, Llc | Methods of enhancing drug delivery and effectiveness of therapeutic agents |
| US9393318B2 (en) | 2010-03-29 | 2016-07-19 | Abraxis Bioscience, Llc | Methods of treating cancer |
| MX347225B (es) | 2010-06-04 | 2017-04-19 | Abraxis Bioscience Llc * | Metodos de tratamiento contra el cancer pancreatico. |
| ES2819204T3 (es) | 2011-04-28 | 2021-04-15 | Abraxis Bioscience Llc | Administración intravascular de composiciones de nanopartículas y usos de las mismas |
| US9585960B2 (en) | 2011-12-14 | 2017-03-07 | Abraxis Bioscience, Llc | Use of polymeric excipients for lyophilization or freezing of particles |
| US9149455B2 (en) | 2012-11-09 | 2015-10-06 | Abraxis Bioscience, Llc | Methods of treating melanoma |
| US20140186447A1 (en) * | 2012-12-28 | 2014-07-03 | Abraxis Bioscience, Llc | Nanoparticle compositions of albumin and paclitaxel |
| US9511046B2 (en) | 2013-01-11 | 2016-12-06 | Abraxis Bioscience, Llc | Methods of treating pancreatic cancer |
| ES2804323T3 (es) | 2013-03-12 | 2021-02-05 | Abraxis Bioscience Llc | Procedimientos de tratamiento de cáncer de pulmón |
| SG11201507234UA (en) | 2013-03-14 | 2015-10-29 | Abraxis Bioscience Llc | Methods of treating bladder cancer |
| KR102245421B1 (ko) | 2013-05-30 | 2021-04-29 | 큐라디즘 | 약학적 조성물, 이의 제조방법 및 이의 용도 |
| US20150247204A1 (en) * | 2014-02-07 | 2015-09-03 | The General Hopital Corporation | Differential diagnosis of hepatic neoplasms |
| PT3229843T (pt) * | 2014-11-25 | 2020-03-06 | Curadigm Sas | Composição farmacêutica, a sua preparação e as suas utilizações |
| BR112017010953B1 (pt) | 2014-11-25 | 2024-01-16 | Curadigm Sas | Composição farmacêutica contendo a combinação de um lipossoma e um carreador que compreende um composto farmacêutico |
| TW201628610A (zh) | 2014-11-25 | 2016-08-16 | 奈諾生技公司 | 醫藥組合物、其製備及其用途 |
| HUE062561T2 (hu) | 2014-11-25 | 2023-11-28 | Curadigm Sas | Legalább két eltérõ nanorészecskéket és egy gyógyászati vegyületet kombináló gyógyászati készítmény, annak elõállítása és alkalmazásai |
| US10705070B1 (en) | 2015-03-05 | 2020-07-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug |
| US10527604B1 (en) | 2015-03-05 | 2020-01-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel |
| JP2018516256A (ja) | 2015-05-28 | 2018-06-21 | ナノビオティックスＮａｎｏｂｉｏｔｉｘ | 治療用ワクチンとしての使用のためのナノ粒子 |
| CN108024999A (zh) | 2015-06-29 | 2018-05-11 | 阿布拉科斯生物科学有限公司 | 治疗上皮样细胞肿瘤的方法 |
| CA3039582A1 (en) * | 2016-10-07 | 2018-04-12 | Abraxis Bioscience, Llc | Methods of treating biliary tract cancer |
| CN110062622B (zh) | 2016-10-27 | 2022-10-14 | 珠海贝海生物技术有限公司 | 多西他赛和人血清白蛋白的中性pH组合物 |
| US10896749B2 (en) * | 2017-01-27 | 2021-01-19 | Shire Human Genetic Therapies, Inc. | Drug monitoring tool |
| CN107828887A (zh) * | 2017-10-12 | 2018-03-23 | 上海市东方医院 | Stmn1基因的用途 |
| CN112188892A (zh) | 2018-03-20 | 2021-01-05 | 阿布拉科斯生物科学有限公司 | 通过mTOR抑制剂和白蛋白的纳米颗粒的施用治疗中枢神经系统障碍的方法 |
| CN115003284A (zh) | 2019-10-28 | 2022-09-02 | 阿布拉科斯生物科学有限公司 | 白蛋白和雷帕霉素的药物组合物 |
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