CA3048635A1 - Optimized strategy for exon skipping modifications using crispr/cas9 with triple guide sequences - Google Patents

Optimized strategy for exon skipping modifications using crispr/cas9 with triple guide sequences Download PDF

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CA3048635A1
CA3048635A1 CA3048635A CA3048635A CA3048635A1 CA 3048635 A1 CA3048635 A1 CA 3048635A1 CA 3048635 A CA3048635 A CA 3048635A CA 3048635 A CA3048635 A CA 3048635A CA 3048635 A1 CA3048635 A1 CA 3048635A1
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sequence encoding
promoter
sequence
nucleic acid
vector
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French (fr)
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Leonela AMOASII
Eric Olson
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University of Texas System
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University of Texas System
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CA3048635A 2017-01-05 2018-01-05 Optimized strategy for exon skipping modifications using crispr/cas9 with triple guide sequences Pending CA3048635A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762442606P 2017-01-05 2017-01-05
US62/442,606 2017-01-05
US201762544449P 2017-08-11 2017-08-11
US62/544,449 2017-08-11
US201762596298P 2017-12-08 2017-12-08
US62/596,298 2017-12-08
PCT/US2018/012558 WO2018129296A1 (en) 2017-01-05 2018-01-05 Optimized strategy for exon skipping modifications using crispr/cas9 with triple guide sequences

Publications (1)

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CA3048635A1 true CA3048635A1 (en) 2018-07-12

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CA3048635A Pending CA3048635A1 (en) 2017-01-05 2018-01-05 Optimized strategy for exon skipping modifications using crispr/cas9 with triple guide sequences

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US (1) US20190338311A1 (https=)
EP (1) EP3565897B1 (https=)
JP (1) JP2020503869A (https=)
KR (1) KR102606174B1 (https=)
CN (1) CN110506115A (https=)
AU (1) AU2018205521A1 (https=)
BR (1) BR112019013962A2 (https=)
CA (1) CA3048635A1 (https=)
CL (1) CL2019001882A1 (https=)
CO (1) CO2019008181A2 (https=)
CR (1) CR20190326A (https=)
DK (1) DK3565897T3 (https=)
DO (1) DOP2019000179A (https=)
EC (1) ECSP19056408A (https=)
IL (1) IL267786A (https=)
JO (1) JOP20190166A1 (https=)
MA (1) MA47239A (https=)
MX (1) MX2019008064A (https=)
PE (1) PE20191357A1 (https=)
PH (1) PH12019501561A1 (https=)
SG (1) SG11201906147VA (https=)
WO (1) WO2018129296A1 (https=)

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EP3810775A1 (en) * 2018-06-21 2021-04-28 The Board Of Regents Of The University Of Texas System Correction of dystrophin exon 43, exon 45, or exon 52 deletions in duchenne muscular dystrophy
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JP2022526669A (ja) * 2019-04-12 2022-05-25 デューク ユニバーシティ ジストロフィン機能を修復するためのＣＲＩＳＰＲ／Ｃａｓをベースにした塩基編集組成物
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CN110499333A (zh) * 2019-08-01 2019-11-26 广州德赫生物科技有限公司 用于修复dmd基因突变的核酸序列及系统
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CN114846146B (zh) * 2019-10-29 2024-04-12 基恩科雷有限责任公司 用于增加CRISPR/Cas12f1系统的效率的工程化引导RNA及其用途
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KR20230134098A (ko) * 2022-03-10 2023-09-20 주식회사 진코어 듀센 근이영양증 치료를 위한 유전자 편집 시스템 및 이를 이용한 질병 치료 방법
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CO2019008181A2 (es) 2019-10-31
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