CA3024976A1 - Treatment for parkinson's disease - Google Patents

Treatment for parkinson's disease Download PDF

Info

Publication number
CA3024976A1
CA3024976A1 CA3024976A CA3024976A CA3024976A1 CA 3024976 A1 CA3024976 A1 CA 3024976A1 CA 3024976 A CA3024976 A CA 3024976A CA 3024976 A CA3024976 A CA 3024976A CA 3024976 A1 CA3024976 A1 CA 3024976A1
Authority
CA
Canada
Prior art keywords
formula
compound
alkyl
hydrogen
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3024976A
Other languages
English (en)
French (fr)
Inventor
Nitin Krishnaji Damle
Sanjay Nandlalji MANDHANE
Manoj Atmaramji UPADHYA
Sameer Vishwanath MEHETRE
Gajanan Uttamrao CHIDREWAR
Prabal Sengupta
Trinadha Rao Chitturi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sun Pharma Advanced Research Co Ltd
Original Assignee
Sun Pharma Advanced Research Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharma Advanced Research Co Ltd filed Critical Sun Pharma Advanced Research Co Ltd
Publication of CA3024976A1 publication Critical patent/CA3024976A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3024976A 2016-06-02 2017-06-02 Treatment for parkinson's disease Pending CA3024976A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN201621019087 2016-06-02
IN201621019185 2016-06-02
IN201621019087 2016-06-02
IN201621019185 2016-06-02
PCT/IN2017/050224 WO2017208267A1 (en) 2016-06-02 2017-06-02 Treatment for parkinson's disease

Publications (1)

Publication Number Publication Date
CA3024976A1 true CA3024976A1 (en) 2017-12-07

Family

ID=59388123

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3024976A Pending CA3024976A1 (en) 2016-06-02 2017-06-02 Treatment for parkinson's disease

Country Status (27)

Country Link
US (4) US10849887B2 (OSRAM)
EP (2) EP4085912A1 (OSRAM)
JP (1) JP6974357B2 (OSRAM)
KR (1) KR102508288B1 (OSRAM)
CN (1) CN109475539B (OSRAM)
AU (1) AU2017273415B2 (OSRAM)
CA (1) CA3024976A1 (OSRAM)
CL (1) CL2018003431A1 (OSRAM)
CY (1) CY1125285T1 (OSRAM)
DK (1) DK3463351T3 (OSRAM)
ES (1) ES2914782T3 (OSRAM)
HR (1) HRP20220683T1 (OSRAM)
HU (1) HUE059387T2 (OSRAM)
IL (1) IL263188B (OSRAM)
LT (1) LT3463351T (OSRAM)
MX (1) MX385276B (OSRAM)
MY (1) MY193754A (OSRAM)
NZ (1) NZ748592A (OSRAM)
PH (1) PH12018502457B1 (OSRAM)
PL (1) PL3463351T3 (OSRAM)
PT (1) PT3463351T (OSRAM)
RS (1) RS63243B1 (OSRAM)
SG (1) SG11201810294QA (OSRAM)
SI (1) SI3463351T1 (OSRAM)
SM (1) SMT202200228T1 (OSRAM)
UA (1) UA123018C2 (OSRAM)
WO (1) WO2017208267A1 (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4238566A1 (en) 2012-05-02 2023-09-06 Georgetown University Treating amyotrophic lateral sclerosis with tyrosine kinase inhibitors
JP6974357B2 (ja) 2016-06-02 2021-12-01 スン プハルマ アドバンセド リサーチ カンパニー リミテド パーキンソン病の治療
CN110606840A (zh) 2018-06-15 2019-12-24 日产化学株式会社 5-炔基吡啶化合物的制造方法
WO2020106825A1 (en) 2018-11-20 2020-05-28 Georgetown University Compositions and methods for treating neurodegenerative, myodegenerative, and lysosomal storage disorders
PH12021553098A1 (en) * 2019-06-11 2023-08-14 Sun Pharma Advanced Res Co Ltd Treatment for synucleinopathies
WO2021030783A1 (en) * 2019-08-15 2021-02-18 Duke University Compositions and methods for the treatment cancer and cns disorders
US20230301982A1 (en) 2020-07-31 2023-09-28 Sun Pharma Advanced Research Company Limited N'-(2-chloro-6-methylbenzoyl)-4-methyl-3-[2-(3-quinolyl)ethynyl]-benzohydrazide for treatment of alzheimer's disease
AU2023265569A1 (en) 2022-05-02 2024-11-07 Sun Pharma Advanced Research Company Limited Vodobatinib for reducing progression of parkinson's disease
KR20250040552A (ko) 2023-09-14 2025-03-24 주식회사 엑소스템텍 퇴행성 뇌질환 치료 단백질을 포함하는 엑소좀을 이용한 뇌 특이적 퇴행성 뇌질환 치료 단백질 전달 기술

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA024194B8 (ru) * 2011-01-21 2016-11-30 Сан Фарма Адвансед Ресьорч Компани Лтд Содержащие диарилацетиленгидразид ингибиторы тирозинкиназы
EP4238566A1 (en) 2012-05-02 2023-09-06 Georgetown University Treating amyotrophic lateral sclerosis with tyrosine kinase inhibitors
US10150733B2 (en) 2015-05-18 2018-12-11 Sun Pharma Advanced Research Company Ltd. Amidoheteroaryl aroyl hydrazide ethynes
JP6974357B2 (ja) * 2016-06-02 2021-12-01 スン プハルマ アドバンセド リサーチ カンパニー リミテド パーキンソン病の治療

Also Published As

Publication number Publication date
JP6974357B2 (ja) 2021-12-01
ES2914782T3 (es) 2022-06-16
PH12018502457B1 (en) 2022-01-12
EP3463351B1 (en) 2022-04-27
IL263188B (en) 2021-08-31
SI3463351T1 (sl) 2022-07-29
US20220273632A1 (en) 2022-09-01
BR112018074439A2 (pt) 2019-03-06
US20190275017A1 (en) 2019-09-12
PT3463351T (pt) 2022-06-02
SMT202200228T1 (it) 2022-07-21
KR102508288B1 (ko) 2023-03-09
CY1125285T1 (el) 2025-03-28
US11813252B2 (en) 2023-11-14
SG11201810294QA (en) 2018-12-28
DK3463351T3 (da) 2022-06-07
US11583522B2 (en) 2023-02-21
US20240066014A1 (en) 2024-02-29
US10849887B2 (en) 2020-12-01
AU2017273415A1 (en) 2018-12-06
LT3463351T (lt) 2022-06-10
IL263188A (en) 2018-12-31
AU2017273415B2 (en) 2023-01-19
CN109475539A (zh) 2019-03-15
US20210015805A1 (en) 2021-01-21
HRP20220683T1 (hr) 2022-07-08
MX2018014944A (es) 2019-03-07
KR20190015257A (ko) 2019-02-13
UA123018C2 (uk) 2021-02-03
NZ748592A (en) 2025-11-28
CN109475539B (zh) 2021-12-28
WO2017208267A1 (en) 2017-12-07
PL3463351T3 (pl) 2022-06-20
EP4085912A1 (en) 2022-11-09
PH12018502457A1 (en) 2019-10-21
CL2018003431A1 (es) 2019-05-10
RS63243B1 (sr) 2022-06-30
MY193754A (en) 2022-10-27
MX385276B (es) 2025-03-18
EP3463351A1 (en) 2019-04-10
HUE059387T2 (hu) 2022-11-28
JP2019520344A (ja) 2019-07-18

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