CA3020580A1 - Peptide compounds to regulate the complement system - Google Patents
Peptide compounds to regulate the complement system Download PDFInfo
- Publication number
- CA3020580A1 CA3020580A1 CA3020580A CA3020580A CA3020580A1 CA 3020580 A1 CA3020580 A1 CA 3020580A1 CA 3020580 A CA3020580 A CA 3020580A CA 3020580 A CA3020580 A CA 3020580A CA 3020580 A1 CA3020580 A1 CA 3020580A1
- Authority
- CA
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- Prior art keywords
- peptide
- complement
- seq
- activation
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A61K38/1725—Complement proteins, e.g. anaphylatoxin, C3a or C5a
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/12011—Astroviridae
- C12N2770/12022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
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- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36620410P | 2010-07-21 | 2010-07-21 | |
| US61/366204 | 2010-07-21 | ||
| CA2804998A CA2804998C (en) | 2010-07-21 | 2011-07-21 | Peptide compounds to regulate the complement system |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2804998A Division CA2804998C (en) | 2010-07-21 | 2011-07-21 | Peptide compounds to regulate the complement system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3020580A1 true CA3020580A1 (en) | 2012-01-26 |
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ID=45497454
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3020580A Abandoned CA3020580A1 (en) | 2010-07-21 | 2011-07-21 | Peptide compounds to regulate the complement system |
| CA2804998A Active CA2804998C (en) | 2010-07-21 | 2011-07-21 | Peptide compounds to regulate the complement system |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2804998A Active CA2804998C (en) | 2010-07-21 | 2011-07-21 | Peptide compounds to regulate the complement system |
Country Status (7)
| Country | Link |
|---|---|
| US (11) | US8906845B2 (enExample) |
| EP (3) | EP2606058B1 (enExample) |
| JP (1) | JP6033774B2 (enExample) |
| CA (2) | CA3020580A1 (enExample) |
| ES (2) | ES2626182T3 (enExample) |
| PL (2) | PL3178841T3 (enExample) |
| WO (1) | WO2012012600A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10005818B2 (en) | 2010-07-21 | 2018-06-26 | Realta Holdings, Llc | Derivative peptide compounds and methods of use |
| CA3020580A1 (en) | 2010-07-21 | 2012-01-26 | Realta Holdings, Llc | Peptide compounds to regulate the complement system |
| ES3044832T3 (en) | 2011-06-22 | 2025-11-27 | Apellis Pharmaceuticals Inc | Methods of treating chronic disorders with complement inhibitors |
| US20150104445A1 (en) * | 2013-10-10 | 2015-04-16 | Viropharma Holdings Limited | Methods of inhibiting the alternative pathway of complement immune system activation and compositions used therein |
| US10010447B2 (en) | 2013-12-18 | 2018-07-03 | Novartis Ag | Systems and methods for subretinal delivery of therapeutic agents |
| PL3313865T3 (pl) * | 2015-06-26 | 2021-10-25 | Realta Holdings, Llc | Syntetyczne związki peptydowe i sposoby zastosowania |
| US10947279B2 (en) | 2015-06-26 | 2021-03-16 | Realta Holdings, Llc | Synthetic peptide compounds and methods of use |
| CN106646992B (zh) * | 2016-12-07 | 2018-06-15 | 深圳市华星光电技术有限公司 | 一种彩膜基板、液晶面板、液晶显示装置及其制备方法 |
| CN108210503A (zh) * | 2016-12-10 | 2018-06-29 | 高尚先 | 甘露糖在用于提高Treg细胞数量及其Foxp3因子表达水平的新用途 |
| TWI881481B (zh) * | 2017-08-15 | 2025-04-21 | 美商歐米諾斯公司 | 用於治療和／或預防與造血幹細胞移植有關的移植物抗宿主病和／或瀰漫性肺泡出血和／或靜脈閉塞性病的方法 |
| KR20220104268A (ko) | 2018-01-09 | 2022-07-26 | 레알타 홀딩스, 엘엘씨 | 동물 모델에서의 미엘로퍼옥시다제 산화 활성의 pic1 억제 |
| KR20230078733A (ko) * | 2020-09-30 | 2023-06-02 | 리얼타 라이프 사이언시즈, 인크. | 펩티드 및 사용 방법 |
| MX2023005135A (es) * | 2020-11-02 | 2023-05-26 | Realta Life Sciences Inc | Peptidos y metodos de uso. |
| CA3194442A1 (en) * | 2020-11-02 | 2022-05-05 | Neel K. Krishna | Peptides and methods of use |
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| KR101132287B1 (ko) | 2003-09-05 | 2012-04-05 | 도레이 도넨 기노마쿠 고도가이샤 | 열가소성 수지 미다공막의 제조 방법 |
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| WO2005023195A2 (en) | 2003-09-05 | 2005-03-17 | University Of Louisville Research Foundation, Inc. | Treatment of spinal cord injury |
| US8501705B2 (en) | 2003-09-11 | 2013-08-06 | The Board Of Regents Of The University Of Texas System | Methods and materials for treating autoimmune and/or complement mediated diseases and conditions |
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| US8840893B2 (en) | 2004-06-10 | 2014-09-23 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
| CA2655371C (en) | 2006-06-15 | 2017-06-20 | Eastern Virginia Medical School | Methods for regulating complement cascade proteins using astrovirus coat protein and derivatives thereof |
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| CA2867611A1 (en) | 2012-03-16 | 2013-09-19 | Belrose Pharma, Inc. | Polymeric conjugates of c1-inhibitors |
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