CA3015835A1 - Derivation of embryonic stem cells - Google Patents
Derivation of embryonic stem cellsInfo
- Publication number
- CA3015835A1 CA3015835A1 CA3015835A CA3015835A CA3015835A1 CA 3015835 A1 CA3015835 A1 CA 3015835A1 CA 3015835 A CA3015835 A CA 3015835A CA 3015835 A CA3015835 A CA 3015835A CA 3015835 A1 CA3015835 A1 CA 3015835A1
- Authority
- CA
- Canada
- Prior art keywords
- cell
- cells
- blastomere
- embryo
- derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0604—Whole embryos; Culture medium therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/119—Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/90—Polysaccharides
- C12N2501/91—Heparin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/02—Coculture with; Conditioned medium produced by embryonic cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- Animal Behavior & Ethology (AREA)
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Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62482704P | 2004-11-04 | 2004-11-04 | |
| US60/624,827 | 2004-11-04 | ||
| US66248905P | 2005-03-15 | 2005-03-15 | |
| US60/662,489 | 2005-03-15 | ||
| US68715805P | 2005-06-03 | 2005-06-03 | |
| US60/687,158 | 2005-06-03 | ||
| US72306605P | 2005-10-03 | 2005-10-03 | |
| US60/723,066 | 2005-10-03 | ||
| US72677505P | 2005-10-14 | 2005-10-14 | |
| US60/726,775 | 2005-10-14 | ||
| CA2588088A CA2588088C (en) | 2004-11-04 | 2005-11-04 | Derivation of embryonic stem cells |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2588088A Division CA2588088C (en) | 2004-11-04 | 2005-11-04 | Derivation of embryonic stem cells |
Publications (1)
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| CA3015835A1 true CA3015835A1 (en) | 2006-05-18 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
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| CA3015835A Abandoned CA3015835A1 (en) | 2004-11-04 | 2005-11-04 | Derivation of embryonic stem cells |
| CA2588088A Expired - Lifetime CA2588088C (en) | 2004-11-04 | 2005-11-04 | Derivation of embryonic stem cells |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2588088A Expired - Lifetime CA2588088C (en) | 2004-11-04 | 2005-11-04 | Derivation of embryonic stem cells |
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| EP (3) | EP2479256A1 (enExample) |
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| HK (1) | HK1219295A1 (enExample) |
| WO (1) | WO2006052646A2 (enExample) |
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| SG188122A1 (en) | 2004-01-23 | 2013-03-28 | Advanced Cell Tech Inc | Improved modalities for the treatment of degenerative diseases of the retina |
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| US7622108B2 (en) | 2004-04-23 | 2009-11-24 | Bioe, Inc. | Multi-lineage progenitor cells |
| CA3015835A1 (en) * | 2004-11-04 | 2006-05-18 | Astellas Institute For Regenerative Medicine | Derivation of embryonic stem cells |
| US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
| GB0507755D0 (en) * | 2005-04-16 | 2005-05-25 | Univ Sheffield | Cytotrophoblast stem cells |
| CA2659945C (en) | 2005-08-03 | 2014-12-16 | Advanced Cell Technology, Inc. | Improved methods of reprogramming animal somatic cells |
| US7727763B2 (en) * | 2006-04-17 | 2010-06-01 | Bioe, Llc | Differentiation of multi-lineage progenitor cells to respiratory epithelial cells |
| KR101602951B1 (ko) * | 2006-05-03 | 2016-03-14 | 오카타 세라퓨틱스, 인크. | 배아 줄기 세포 및 배-유도 세포의 유도 |
| US20070298496A1 (en) * | 2006-06-23 | 2007-12-27 | Hung-Chih Kuo | Method of deriving pluripotent stem cells from a single blastomere |
| EP3190178A1 (en) * | 2007-02-23 | 2017-07-12 | Astellas Institute for Regenerative Medicine | Highly efficient methods for reprogramming differentiated cells and for generating animals and embryonic stem cells from reprogrammed cells |
| ES2764473T3 (es) | 2007-10-12 | 2020-06-03 | Astellas Inst For Regenerative Medicine | Métodos mejorados para producir células RPE y composiciones de células RPE |
| WO2009067757A1 (en) * | 2007-11-30 | 2009-06-04 | Cytomatrix Pty Ltd | Methods of inducing pluripotency involving oct4 protein |
| EP2100954A1 (en) * | 2008-03-10 | 2009-09-16 | Assistance Publique - Hopitaux de Paris | Method for generating primate cardiac progenitor cells for clinical use from primate embryonic stem cells, and their applications |
| JP2009225675A (ja) * | 2008-03-19 | 2009-10-08 | Tohoku Univ | 上皮系細胞シートの作製のための同種皮膚由来フィーダー細胞 |
| DK2322611T3 (en) | 2008-07-16 | 2016-09-05 | Ip Pharma Co Ltd | A process for producing reprogrammed cells using chromosomally non-integrated viral vector |
| EP2473598B1 (en) * | 2009-09-04 | 2017-03-22 | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services | Methods for enhancing genome stability and telomere elongation in embryonic stem cells |
| WO2011063005A2 (en) | 2009-11-17 | 2011-05-26 | Advanced Cell Technology, Inc. | Methods of producing human rpe cells and pharmaceutical preparations of human rpe cells |
| EP4245370A3 (en) | 2010-07-12 | 2023-11-29 | University of Southern California | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| ES2874953T3 (es) * | 2010-07-23 | 2021-11-05 | Astellas Inst For Regenerative Medicine | Métodos para la detección de subpoblaciones raras de células y composiciones muy purificadas de células |
| WO2012013936A1 (en) * | 2010-07-30 | 2012-02-02 | Cambridge Enterprise Limited | Corticogenesis of human pluripotent cells |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
| US10478206B2 (en) | 2011-04-29 | 2019-11-19 | University Of Southern California | Instruments and methods for the implantation of cell-seeded substrates |
| WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
| HK1202251A1 (en) * | 2011-11-07 | 2015-09-25 | Hina W. Chaudhry | Methods of cardiac repair |
| CA2855941A1 (en) | 2011-11-14 | 2013-05-23 | Advanced Cell Technology, Inc. | Pharmaceutical preparations of human rpe cells and uses thereof |
| US9248013B2 (en) | 2011-12-05 | 2016-02-02 | California Institute Of Technology | 3-Dimensional parylene scaffold cage |
| EP3080248A1 (en) | 2013-12-11 | 2016-10-19 | Pfizer Limited | Method for producing retinal pigment epithelial cells |
| WO2016005985A2 (en) | 2014-07-09 | 2016-01-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Method for reprogramming cells |
| KR102473092B1 (ko) | 2014-09-15 | 2022-12-01 | 칠드런'즈 메디컬 센터 코포레이션 | 히스톤 h3-리신 트리메틸화를 제거함으로써 체세포 핵 이식(scnt) 효율을 증가시키는 방법 및 조성물 |
| EP4343331A3 (en) | 2015-03-23 | 2024-06-19 | Astellas Institute for Regenerative Medicine | Improved assays for potency of human retinal pigment epithelium (rpe) cells and photoreceptor progenitors |
| MX2022005134A (es) | 2019-10-30 | 2022-05-30 | Astellas Inst For Regenerative Medicine | Metodos para producir celulas del epitelio pigmentario retiniano. |
| JP2024519218A (ja) | 2021-05-03 | 2024-05-09 | アステラス インスティテュート フォー リジェネレイティブ メディシン | 成熟角膜内皮細胞を作製する方法 |
| CA3217861A1 (en) | 2021-05-07 | 2022-11-10 | Astellas Institute For Regenerative Medicine | Methods of generating mature hepatocytes |
| CA3230677A1 (en) | 2021-06-13 | 2022-12-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Method for reprogramming human cells |
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| US6274705B1 (en) * | 1996-05-02 | 2001-08-14 | Aventis Pharmaceuticals Products Inc. | Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides |
| AU1439295A (en) * | 1993-12-17 | 1995-07-03 | Abs Global, Inc. | Ungulate preblastocyst derived embryonic stem cells and use thereof to produce cloned transgenic and chimeric ungulates |
| EP0739412B1 (en) * | 1993-12-23 | 2002-02-27 | Infigen, Inc. | ungulate EMBRYONIC STEM CELLS AS NUCLEAR DONORS AND NUCLEAR TRANSFER TECHNIQUES TO PRODUCE CHIMERIC AND TRANSGENIC ANIMALS |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
| US20040199935A1 (en) | 1999-06-30 | 2004-10-07 | Chapman Karen B. | Cytoplasmic transfer to de-differentiate recipient cells |
| BR0014864A (pt) | 1999-10-15 | 2002-11-19 | Advanced Cell Tech Inc | Métodos de produzir células progenitoras diferenciadas e células tronco embriÈnicas defeituosas em linhagem |
| CN1425064A (zh) | 1999-12-20 | 2003-06-18 | 马萨诸塞大学 | 通过交叉物种核移植制备的胚胎或干样细胞 |
| WO2001050848A2 (en) * | 2000-01-07 | 2001-07-19 | Oregon Health And Science University | Clonal propagation of primate offspring by embryo splitting |
| US20030105082A1 (en) * | 2001-12-03 | 2003-06-05 | Murphy Greer Marechal | Methods for improving the therapeutic response of humans having major depression and carrying the gene for apolipoprotein E4 |
| DE10108412B4 (de) | 2001-02-21 | 2006-03-09 | Cevec Pharmaceuticals Gmbh | Pigmentepithelzelle des Auges, ihre Herstellung und Verwendung in der Therapie einer Augen- oder Nervenerkrankung |
| US20030082598A1 (en) | 2001-08-22 | 2003-05-01 | Ecker David J. | Molecular interaction sites of 23S ribosomal RNA and methods of modulating the same |
| IL160507A0 (en) | 2001-08-24 | 2004-07-25 | Advanced Cell Tech Inc | Screening assays for identifying differentiation-inducing agents and production of differentiated cells for cell therapy |
| US7247477B2 (en) * | 2002-04-16 | 2007-07-24 | Technion Research & Development Foundation Ltd. | Methods for the in-vitro identification, isolation and differentiation of vasculogenic progenitor cells |
| US6699771B1 (en) * | 2002-08-06 | 2004-03-02 | Texas Instruments Incorporated | Process for optimizing junctions formed by solid phase epitaxy |
| AU2003296480A1 (en) * | 2002-12-10 | 2004-06-30 | The Wistar Institute | Method for programmed differentiation of stem cells |
| US20050118713A1 (en) | 2003-05-12 | 2005-06-02 | Nikolai Strelchenko | Morula derived embryonic stem cells |
| US20040229350A1 (en) * | 2003-05-12 | 2004-11-18 | Nikolai Strelchenko | Morula derived embryonic stem cells |
| TW200521236A (en) | 2003-12-22 | 2005-07-01 | Animal Technology Inst Taiwan | Method for generating non-human mammalian chimeric embryo |
| SG188122A1 (en) | 2004-01-23 | 2013-03-28 | Advanced Cell Tech Inc | Improved modalities for the treatment of degenerative diseases of the retina |
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| WO2005080551A2 (en) | 2004-02-12 | 2005-09-01 | University Of Newcastle Upon Tyne | Stem cells |
| WO2006013519A1 (en) | 2004-07-26 | 2006-02-09 | Koninklijke Philips Electronics N.V. | Method of storing data in an information carrier, system for reading such an information carrier. |
| US20080262321A1 (en) | 2004-08-06 | 2008-10-23 | Ramot At Tel Aviv University Ltd. | Early Detection of Harmful Agents: Method, System and Kit |
| US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
| CA3015835A1 (en) | 2004-11-04 | 2006-05-18 | Astellas Institute For Regenerative Medicine | Derivation of embryonic stem cells |
| US7818929B2 (en) * | 2004-12-14 | 2010-10-26 | Anthony Hardwood Composites, Inc. | Laminated support mat |
| JP5451073B2 (ja) * | 2005-10-14 | 2014-03-26 | ユニセンス・ファーティリテック・アクティーゼルスカブ | 細胞集団における変化の決定 |
| EP1847595B1 (en) * | 2006-04-20 | 2010-01-06 | Northern Sydney and Central Coast Area Health Service | Methods of assessing embryo viability |
| KR101602951B1 (ko) * | 2006-05-03 | 2016-03-14 | 오카타 세라퓨틱스, 인크. | 배아 줄기 세포 및 배-유도 세포의 유도 |
| US20070298496A1 (en) | 2006-06-23 | 2007-12-27 | Hung-Chih Kuo | Method of deriving pluripotent stem cells from a single blastomere |
| EP3190178A1 (en) | 2007-02-23 | 2017-07-12 | Astellas Institute for Regenerative Medicine | Highly efficient methods for reprogramming differentiated cells and for generating animals and embryonic stem cells from reprogrammed cells |
| EA020593B1 (ru) * | 2009-01-13 | 2014-12-30 | Флуидигм Корпорейшн | Анализ нуклеиновых кислот, полученных из единичных клеток |
| WO2012163363A1 (en) * | 2011-05-31 | 2012-12-06 | Unisense Fertilitech A/S | Embryo quality assessment based on blastomere cleavage and morphology |
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- 2005-11-04 AU AU2005304978A patent/AU2005304978A1/en not_active Abandoned
- 2005-11-04 EP EP11000551A patent/EP2479256A1/en not_active Withdrawn
- 2005-11-04 US US11/267,555 patent/US7838727B2/en active Active
- 2005-11-04 CA CA2588088A patent/CA2588088C/en not_active Expired - Lifetime
- 2005-11-04 EP EP15164137.0A patent/EP2960328A1/en not_active Ceased
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- 2005-11-04 EP EP05819524A patent/EP1812554A4/en not_active Withdrawn
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2010
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2014
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2016
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- 2016-12-23 US US15/390,319 patent/US20170204368A1/en not_active Abandoned
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| EP2960328A1 (en) | 2015-12-30 |
| CA2588088C (en) | 2018-10-09 |
| US20110150842A1 (en) | 2011-06-23 |
| AU2005304978A1 (en) | 2006-05-18 |
| HK1219295A1 (en) | 2017-03-31 |
| US20170204368A1 (en) | 2017-07-20 |
| WO2006052646A2 (en) | 2006-05-18 |
| US20140377865A1 (en) | 2014-12-25 |
| JP2008518616A (ja) | 2008-06-05 |
| EP1812554A2 (en) | 2007-08-01 |
| US8642328B2 (en) | 2014-02-04 |
| JP5728676B2 (ja) | 2015-06-03 |
| WO2006052646A3 (en) | 2006-09-28 |
| JP5841926B2 (ja) | 2016-01-13 |
| US7838727B2 (en) | 2010-11-23 |
| CA2588088A1 (en) | 2006-05-18 |
| EP2479256A1 (en) | 2012-07-25 |
| US20060206953A1 (en) | 2006-09-14 |
| JP2013046623A (ja) | 2013-03-07 |
| US9550974B2 (en) | 2017-01-24 |
| EP1812554A4 (en) | 2008-10-08 |
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