CA3010764A1 - Methods and vectors to produce vector free induced pluripotent stem cells - Google Patents
Methods and vectors to produce vector free induced pluripotent stem cells Download PDFInfo
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- CA3010764A1 CA3010764A1 CA3010764A CA3010764A CA3010764A1 CA 3010764 A1 CA3010764 A1 CA 3010764A1 CA 3010764 A CA3010764 A CA 3010764A CA 3010764 A CA3010764 A CA 3010764A CA 3010764 A1 CA3010764 A1 CA 3010764A1
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
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- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
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- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/005—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination repressible enhancer/promoter combination, e.g. KRAB
- C12N2830/006—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination repressible enhancer/promoter combination, e.g. KRAB tet repressible
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| PCT/US2017/013229 WO2017123789A1 (en) | 2016-01-12 | 2017-01-12 | Methods and vectors to produce vector free induced pluripotent stem cells |
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| CA3010764A1 (en) * | 2016-01-12 | 2017-07-20 | Lonza Walkersville, Inc. | Methods and vectors to produce vector free induced pluripotent stem cells |
| CA3078734A1 (en) * | 2017-10-11 | 2019-04-18 | Fate Therapeutics, Inc. | Cellular reprogramming using temporal and transient plasmid vector expression system |
| CN108373998B (zh) * | 2018-02-10 | 2019-08-27 | 安徽中盛溯源生物科技有限公司 | 一种通过蝾螈Oct4将人类血液细胞重编程为iPSC的方法 |
| GB201805683D0 (en) * | 2018-04-05 | 2018-05-23 | Touchlight Ip Ltd | Reprogramming vectors |
| JPWO2019244895A1 (ja) * | 2018-06-18 | 2021-06-24 | パール工業株式会社 | 形質転換細胞の製造方法 |
| CN109679994B (zh) * | 2018-12-13 | 2021-02-02 | 湖北汇智铭传生物科技股份有限公司 | 通过四环素诱导表达外源基因的游离载体及其构建方法 |
| CN116348592A (zh) * | 2020-10-02 | 2023-06-27 | 菲特治疗公司 | 诱导性多能干细胞的改善的重编程、维持和保存 |
| CN114277190B (zh) * | 2021-12-31 | 2024-07-23 | 安徽中盛溯源生物科技有限公司 | 一种hiPSC中外源基因残留检测用特异性DNA片段、引物、试剂盒和检测方法 |
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| EP3447128A1 (en) * | 2008-06-04 | 2019-02-27 | FUJIFILM Cellular Dynamics, Inc. | Methods for the production of ips cells using non-viral approach |
| SG173469A1 (en) * | 2009-02-20 | 2011-09-29 | Ventria Bioscience | Cell culture media containing combinations of proteins |
| CN103087991B (zh) * | 2009-06-05 | 2018-06-12 | 富士胶片细胞动力公司 | 重编程t细胞和造血细胞的方法 |
| ES2539487T3 (es) * | 2009-11-04 | 2015-07-01 | Cellular Dynamics International, Inc. | Reprogramación episómica con compuestos químicos |
| WO2011159797A2 (en) * | 2010-06-15 | 2011-12-22 | Cellular Dynamics International, Inc. | A compendium of ready-built stem cell models for interrogation of biological response |
| US8765470B2 (en) * | 2010-08-04 | 2014-07-01 | Cellular Dynamics International, Inc. | Reprogramming immortalized B-cells to induced pluripotent stem cells |
| JP2014520551A (ja) * | 2011-07-11 | 2014-08-25 | セルラー ダイナミクス インターナショナル， インコーポレイテッド | 細胞のリプログラミング方法およびゲノムの改変方法 |
| WO2013177228A1 (en) * | 2012-05-22 | 2013-11-28 | Loma Linda University | Generation of integration/transgene-free stem cells |
| EP2853592B1 (en) * | 2012-05-23 | 2019-02-20 | Kyoto University | Highly efficient method for establishing artificial pluripotent stem cell |
| WO2015006725A2 (en) * | 2013-07-12 | 2015-01-15 | Cedars-Sinai Medical Center | Generation of induced pluripotent stem cells from normal human mammary epithelial cells |
| SG10201807292YA (en) * | 2014-03-04 | 2018-09-27 | Fate Therapeutics Inc | Improved reprogramming methods and cell culture platforms |
| US20160362705A1 (en) * | 2015-06-12 | 2016-12-15 | Lonza Walkersville, Inc. | Methods for Nuclear Reprogramming Using Synthetic Transcription Factors |
| AU2016318774B2 (en) * | 2015-09-08 | 2022-08-18 | FUJIFILM Cellular Dynamics, Inc. | MACS-based purification of stem cell-derived retinal pigment epithelium |
| US10865381B2 (en) * | 2015-10-20 | 2020-12-15 | FUJIFILM Cellular Dynamics, Inc. | Multi-lineage hematopoietic precursor cell production by genetic programming |
| CA3010764A1 (en) * | 2016-01-12 | 2017-07-20 | Lonza Walkersville, Inc. | Methods and vectors to produce vector free induced pluripotent stem cells |
| CA3078734A1 (en) * | 2017-10-11 | 2019-04-18 | Fate Therapeutics, Inc. | Cellular reprogramming using temporal and transient plasmid vector expression system |
| CN108410823B (zh) * | 2018-03-26 | 2019-11-01 | 安徽中盛溯源生物科技有限公司 | 一种微环游离型载体高效重编程血液细胞生成iPSC的方法 |
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| US20170226483A1 (en) | 2017-08-10 |
| KR20180105670A (ko) | 2018-09-28 |
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