CA2998504C - Sustained release olanzapine formulations - Google Patents
Sustained release olanzapine formulations Download PDFInfo
- Publication number
- CA2998504C CA2998504C CA2998504A CA2998504A CA2998504C CA 2998504 C CA2998504 C CA 2998504C CA 2998504 A CA2998504 A CA 2998504A CA 2998504 A CA2998504 A CA 2998504A CA 2998504 C CA2998504 C CA 2998504C
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- CA
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- Prior art keywords
- olanzapine
- poly
- patient
- dosage form
- pdss
- Prior art date
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- KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 title claims abstract description 199
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
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- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Biological Depolymerization Polymers (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562221290P | 2015-09-21 | 2015-09-21 | |
| US62/221,290 | 2015-09-21 | ||
| PCT/US2016/052757 WO2017053346A1 (en) | 2015-09-21 | 2016-09-21 | Sustained release olanzapine formulations |
Publications (2)
| Publication Number | Publication Date |
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| CA2998504A1 CA2998504A1 (en) | 2017-03-30 |
| CA2998504C true CA2998504C (en) | 2023-06-20 |
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| CA2998504A Active CA2998504C (en) | 2015-09-21 | 2016-09-21 | Sustained release olanzapine formulations |
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| WO2018172850A1 (en) * | 2017-03-20 | 2018-09-27 | Teva Pharmaceuticals International Gmbh | Sustained release olanzapine formulaitons |
| CN111836615A (zh) * | 2018-01-05 | 2020-10-27 | 英倍尔药业股份有限公司 | 通过精密鼻装置的奥氮平的鼻内递送 |
| AU2020410549A1 (en) * | 2019-12-20 | 2022-04-14 | Alar Pharmaceuticals Inc. | Long-acting injectable formulations of ketamine pamoate salts |
| CN112587505A (zh) * | 2020-10-16 | 2021-04-02 | 长春斯菲尔生物科技有限公司 | 一种奥氮平双羟萘酸盐缓释微粒制剂及其制备方法 |
| WO2025188992A1 (en) * | 2024-03-06 | 2025-09-12 | Neurelis, Inc. | Oral film for rapid active delivery |
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-
2016
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- 2016-09-21 HU HUE16775424A patent/HUE063850T2/hu unknown
- 2016-09-21 EP EP23193256.7A patent/EP4331570A1/en active Pending
- 2016-09-21 US US15/271,508 patent/US20170079985A1/en not_active Abandoned
- 2016-09-21 IL IL295161A patent/IL295161A/en unknown
- 2016-09-21 PT PT167754241T patent/PT3352735T/pt unknown
- 2016-09-21 CN CN202310947482.0A patent/CN116942677A/zh active Pending
- 2016-09-21 AU AU2016328958A patent/AU2016328958B2/en active Active
- 2016-09-21 PL PL16775424.1T patent/PL3352735T3/pl unknown
- 2016-09-21 MX MX2018003380A patent/MX2018003380A/es unknown
- 2016-09-21 JP JP2018515050A patent/JP2018527397A/ja active Pending
- 2016-09-21 EA EA201890788A patent/EA201890788A1/ru unknown
- 2016-09-21 EP EP16775424.1A patent/EP3352735B1/en active Active
- 2016-09-21 TW TW105130439A patent/TWI798161B/zh active
- 2016-09-21 ES ES16775424T patent/ES2960753T3/es active Active
- 2016-09-21 DK DK16775424.1T patent/DK3352735T3/da active
- 2016-09-21 CA CA2998504A patent/CA2998504C/en active Active
- 2016-09-21 NZ NZ740665A patent/NZ740665A/en unknown
- 2016-09-21 KR KR1020187007791A patent/KR20180054627A/ko not_active Ceased
- 2016-09-21 CN CN201680066464.XA patent/CN108289834A/zh active Pending
- 2016-09-21 AR ARP160102864A patent/AR106085A1/es not_active Application Discontinuation
- 2016-09-21 FI FIEP16775424.1T patent/FI3352735T3/fi active
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2018
- 2018-03-13 IL IL258086A patent/IL258086A/en unknown
- 2018-03-16 MX MX2022007315A patent/MX2022007315A/es unknown
- 2018-03-20 CL CL2018000727A patent/CL2018000727A1/es unknown
- 2018-05-17 US US15/982,449 patent/US20180264001A1/en not_active Abandoned
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2020
- 2020-06-29 IL IL275735A patent/IL275735A/en unknown
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2021
- 2021-07-01 JP JP2021110240A patent/JP2021167331A/ja active Pending
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2022
- 2022-06-23 US US17/847,685 patent/US20220323458A1/en not_active Abandoned
- 2022-07-18 AU AU2022206695A patent/AU2022206695A1/en not_active Abandoned
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2024
- 2024-04-01 US US18/623,327 patent/US20240238307A1/en not_active Abandoned
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