CA2995827A1 - Fiber-hydrogel composite surgical meshes for tissue repair - Google Patents

Fiber-hydrogel composite surgical meshes for tissue repair Download PDF

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Publication number
CA2995827A1
CA2995827A1 CA2995827A CA2995827A CA2995827A1 CA 2995827 A1 CA2995827 A1 CA 2995827A1 CA 2995827 A CA2995827 A CA 2995827A CA 2995827 A CA2995827 A CA 2995827A CA 2995827 A1 CA2995827 A1 CA 2995827A1
Authority
CA
Canada
Prior art keywords
hydrogel
tissue
fiber
composite
fibers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA2995827A
Other languages
English (en)
French (fr)
Inventor
Russell Martin
Sashank Reddy
Justin SACKS
Xiaowei Li
Brian Honewee Cho
Hai-Quan Mao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Publication of CA2995827A1 publication Critical patent/CA2995827A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/12—Mammary prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L31/129—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0061—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof swellable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/64—Animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/04—Materials or treatment for tissue regeneration for mammary reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Prostheses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA2995827A 2015-08-17 2016-08-17 Fiber-hydrogel composite surgical meshes for tissue repair Pending CA2995827A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562206011P 2015-08-17 2015-08-17
US62/206,011 2015-08-17
PCT/US2016/047282 WO2017031167A1 (en) 2015-08-17 2016-08-17 Fiber-hydrogel composite surgical meshes for tissue repair

Publications (1)

Publication Number Publication Date
CA2995827A1 true CA2995827A1 (en) 2017-02-23

Family

ID=58051311

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2995827A Pending CA2995827A1 (en) 2015-08-17 2016-08-17 Fiber-hydrogel composite surgical meshes for tissue repair

Country Status (8)

Country Link
US (3) US10471181B2 (enExample)
EP (1) EP3337423B1 (enExample)
JP (2) JP7445273B2 (enExample)
KR (1) KR102831575B1 (enExample)
CN (2) CN114949368B (enExample)
AU (1) AU2016308652B2 (enExample)
CA (1) CA2995827A1 (enExample)
WO (1) WO2017031167A1 (enExample)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2470228B1 (en) 2009-08-28 2017-10-04 Sernova Corporation Methods and devices for cellular transplantation
US10149749B2 (en) 2010-06-17 2018-12-11 Washington University Biomedical patches with aligned fibers
US10124089B2 (en) 2012-09-21 2018-11-13 Washington University Method of making biomedical patches with spatially arranged fibers
KR20170070008A (ko) 2014-08-15 2017-06-21 더 존스 홉킨스 유니버시티 조직 복원용 복합 재료
EP3337423B1 (en) * 2015-08-17 2023-06-07 The Johns Hopkins University Fiber-hydrogel composite surgical meshes for tissue repair
HK1254350A1 (zh) 2015-10-23 2019-07-19 纽约市哥伦比亚大学理事会 由激光诱导的组织中的胶原交联
US10632228B2 (en) 2016-05-12 2020-04-28 Acera Surgical, Inc. Tissue substitute materials and methods for tissue repair
WO2017198286A1 (en) * 2016-05-17 2017-11-23 Carl Zeiss Smt Gmbh Mounting arrangement for an optical imaging arrangement
US11497403B2 (en) 2016-06-10 2022-11-15 The Trustees Of Columbia University In The City Of New York Devices, methods, and systems for detection of collagen tissue features
CN108245708B (zh) 2016-12-28 2021-04-23 四川大学华西医院 一种诱导肌腱组织再生的生物活性支架及其制备方法和用途
KR102194468B1 (ko) * 2017-01-26 2020-12-23 가톨릭대학교 산학협력단 생체 모사형 인공방광.
WO2018152149A1 (en) 2017-02-17 2018-08-23 The Research Foundation For The State University Of New York High-flux thin-film nanocomposite reverse osmosis membrane for desalination
GB2560369B (en) 2017-03-10 2020-04-01 Vestlandets Innovasjonsselskap As Tissue engineering scaffolds
WO2019093936A1 (en) * 2017-11-09 2019-05-16 Neuronano Ab Positional stabilization of tissue-implanted medical devices
US11666481B1 (en) 2017-12-01 2023-06-06 The Trustees Of Columbia University In The City Of New York Diagnosis and treatment of collagen-containing tissues
JP2021506319A (ja) * 2017-12-22 2021-02-22 アンスティテュ・パストゥール ヒドロゲル型の生体機能チップマイクロ流体デバイス
WO2019175288A1 (en) 2018-03-13 2019-09-19 Institut Químic De Sarrià Cets Fundació Privada Vascular repair patch
JP7358334B2 (ja) * 2018-03-28 2023-10-10 持田製薬株式会社 新規反応性アルギン酸誘導体
ES3060255T3 (en) * 2018-05-09 2026-03-25 Univ Johns Hopkins Nanofiber-hydrogel composites for enhanced soft tissue replacement and regeneration
EP3790602A1 (en) 2018-05-09 2021-03-17 The Johns Hopkins University Nanofiber-hydrogel composites for cell and tissue delivery
WO2020010330A1 (en) * 2018-07-06 2020-01-09 The Trustees Of Columbia University In The City Of New York Collagen tissue modification
KR102089086B1 (ko) * 2018-08-10 2020-03-13 강원대학교산학협력단 항균성 금속 나노입자가 흡착된 나노섬유를 함유한 알긴산 히드로겔 및 이의 용도, 및 이를 제조하는 방법
US10987321B2 (en) 2018-09-04 2021-04-27 Babak Ghalili Cannabinoid and anesthetic compositions and methods
CN109833519B (zh) * 2018-10-19 2021-03-12 四川大学 一种人工生物瓣膜的方法
JP7202910B2 (ja) * 2019-01-29 2023-01-12 株式会社日本触媒 繊維強化材料、及びその製造方法
EP3705143A1 (en) * 2019-03-04 2020-09-09 Hans U. Baer Biodegradable mesh implant for soft tissue repair, in particular hernia repair
EP3976127B1 (en) * 2019-05-30 2025-09-24 LifeCell Corporation Biologic breast implant
US20220344713A1 (en) * 2019-08-20 2022-10-27 Xerox Corporation Biodegradable electrochemical device
CN111068107A (zh) * 2019-12-27 2020-04-28 上海交通大学 三维仿生自愈水凝胶纤维支架组合物及其制备方法与应用
CN111116827B (zh) * 2020-01-06 2021-11-23 西南石油大学 一种高弹性高韧性凝胶微纳米颗粒及其制备方法
EP4090262A4 (en) * 2020-01-16 2024-02-07 The Johns Hopkins University Composite materials and embolization methods
WO2021177936A1 (en) * 2020-03-02 2021-09-10 Babak Ghalili Cannabinoid and anesthetic compositions and methods
TWI742571B (zh) * 2020-03-18 2021-10-11 美商威斯頓股份有限公司 生物材料及其用於促進組織再生的用途
KR102380400B1 (ko) * 2020-03-27 2022-03-30 주식회사 원바이오젠 사용성이 개선된 유착방지막 및 그 제조방법
US11826028B2 (en) * 2020-06-10 2023-11-28 Ethicon, Inc. Two component sealing systems including synthetic matrices and biosynthetic adhesives for sealing resected surfaces of organs to control bleeding, fluid leaks and air leaks
JP2023534633A (ja) 2020-07-01 2023-08-10 デューク ユニバーシティ 付着ハイドロゲルのナノファイバー強化
KR102468837B1 (ko) * 2020-07-14 2022-11-18 주식회사 피씨지바이오 생체적합성 하이드로겔을 포함하는 온도 감응형 복합 하이드로겔 시트
CN111978559B (zh) * 2020-09-08 2021-10-08 四川大学 具有mof结构的高强度自凝固复合骨植入体及其制备
US20220117722A1 (en) * 2020-10-15 2022-04-21 Expa Medical Devices Permanent expandable prosthetic breast implant and delivery system
US20230405190A1 (en) * 2020-11-04 2023-12-21 Emory University Composite Materials for Uses in Cardiac and Other Tissue Repair
JP2023551694A (ja) 2020-11-30 2023-12-12 エンボディ，インコーポレイテッド 回転フレーム装置及び生体適合性足場構築物
WO2022126021A1 (en) * 2020-12-11 2022-06-16 The Johns Hopkins University Heparinized small-diameter vascular grafts
US20240042101A1 (en) * 2020-12-21 2024-02-08 University Of Washington Photopatterned biomolecule immobilization to guide 3d cell fate in natural protein-based hydrogels
CN113274165B (zh) * 2021-05-06 2022-04-15 东华大学 一体化成型微纳米纤维/水凝胶双网络型人工血管及制法
KR20240016293A (ko) * 2021-05-06 2024-02-06 렁 바이오테크놀로지 피비씨 3d 프린팅된 하이드로겔 물체의 광경화성 강화
US11986999B2 (en) 2021-05-06 2024-05-21 Lung Biotechnology Pbc Modified 3D-printed objects and their uses
EP4376908A4 (en) 2021-07-29 2025-05-28 Acera Surgical, Inc. Combined macro and micro-porous hybrid-scale fiber matrix
JP2024536674A (ja) * 2021-07-29 2024-10-08 アセラ サージカル インコーポレイテッド 粒子状ハイブリッドスケール繊維マトリックス
US12167853B2 (en) 2021-09-07 2024-12-17 Acera Surgical, Inc. Non-woven graft materials for nerve repair and regeneration
US11819578B2 (en) 2021-10-07 2023-11-21 Trustees Of Boston University Nanofiber scaffolds
US11701452B2 (en) 2021-10-12 2023-07-18 Duke University Synthetic hydrogel composite
CN114306750B (zh) * 2021-12-08 2022-08-26 扬州大学 一种h-cnc多取向同轴人工血管及其制备方法
JP2025516300A (ja) 2022-05-04 2025-05-27 デューク ユニバーシティ 合成ヒドロゲル複合体
CN114921236B (zh) * 2022-05-24 2023-02-03 中国石油大学(北京) 一种基于纳米材料缔合的自修复交互网络结构凝胶及其制备方法和应用
CN115531550B (zh) * 2022-08-17 2024-10-18 东华大学 一种界面稳定的纤维/水凝胶复合支架及其制备方法
US20260102540A1 (en) * 2022-09-30 2026-04-16 The Johns Hopkins University Nanofiber-hydrogel composites and methods for inhibiting adhesion formation
EP4642498A1 (en) * 2022-12-27 2025-11-05 The Johns Hopkins University Collagen fiber hydrogel composites and methods
KR102837822B1 (ko) * 2023-02-23 2025-07-23 경희대학교 산학협력단 히알루론산의 다공성 폴리머에 아텔로콜라겐을 삽입한 힘줄 또는 인대 질환 치료용 지지체
CN121127278A (zh) * 2023-04-20 2025-12-12 香港中文大学 细胞外基质生物材料的制备和调制方法
WO2025106953A1 (en) * 2023-11-17 2025-05-22 Trustees Of The University Of Pennsylvania Sustained delivery of nitrile-containing jak inhibitors from a hydrogel through reversible thioimidate adducts
CN117547656B (zh) * 2023-11-17 2026-07-28 上海理工大学 一种水凝胶溶石支架及其制备方法和应用
CN119392386A (zh) * 2024-07-31 2025-02-07 浙江工业大学 一种负载头孢氨苄和表儿茶素的α-乳白蛋白电纺纳米纤维的制备方法与应用
WO2026060168A1 (en) * 2024-09-12 2026-03-19 The Johns Hopkins University Thin films for promotion of vascularization and wound healing
WO2026094223A1 (ja) * 2024-10-31 2026-05-07 株式会社メニコン ポリマー材料および眼用レンズ
KR20260101259A (ko) * 2024-12-23 2026-06-30 재단법인 아산사회복지재단 장기 누공 폐색기구 및 이를 포함하는 내시경 장치
CN119732794B (zh) * 2024-12-26 2026-02-17 江南大学 一种双载药负泊松比织物敷料及其制备方法
CN122097688A (zh) * 2026-04-28 2026-05-29 浙江星月生物科技股份有限公司 一种丝素蛋白软组织补片及其制备方法和应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629077A (en) * 1994-06-27 1997-05-13 Advanced Cardiovascular Systems, Inc. Biodegradable mesh and film stent
CA2379909C (en) * 1999-08-06 2011-01-04 Board Of Regents, The University Of Texas System Drug releasing biodegradable fiber implant
CN101035574B (zh) * 2004-04-20 2011-05-11 根茨美公司 外科用丝网状植入物
EP1744795A1 (en) * 2004-05-14 2007-01-24 Becton, Dickinson and Company Articles having bioactive surfaces and solvent-free methods of preparation thereof
GB2417904A (en) * 2004-09-14 2006-03-15 Spinox Ltd Tubular prosthesis for nerve regeneration
WO2008024640A2 (en) * 2006-08-10 2008-02-28 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biodegradable elastomeric scaffolds containing microintegrated cells
US9421305B2 (en) * 2008-02-01 2016-08-23 Wake Forest University Health Sciences Aligned scaffolding system for skeletal muscle regeneration
GB0809592D0 (en) * 2008-05-27 2008-07-02 Imp Innovations Ltd Biomaterials
US20120040461A1 (en) * 2009-02-23 2012-02-16 Beachley Vince Z Fabrication of nanofiber reinforced structures for tissue engineering
US9476026B2 (en) * 2009-03-12 2016-10-25 New Jersey Institute Of Technology Method of tissue repair using a piezoelectric scaffold
US8481067B2 (en) * 2009-06-04 2013-07-09 Clemson University Research Foundation Methods for promoting the revascularization and reenervation of CNS lesions
IN2012DN00368A (enExample) * 2009-07-06 2015-08-21 Coloplast As
BR112012014603A2 (pt) * 2009-12-17 2019-09-24 Univ Kingston método para descelularização de tecido adiposo, tecido adipose descelularizado, tecido adiposo descelularizado incluindo laminina, biosuporte, revestimento, esfera micro-transportadora e partícula
US9144585B2 (en) * 2010-07-27 2015-09-29 Technion Research & Development Foundation Limited Isolated mesenchymal progenitor cells and extracellular matrix produced thereby
KR20170070008A (ko) 2014-08-15 2017-06-21 더 존스 홉킨스 유니버시티 조직 복원용 복합 재료
EP3337423B1 (en) * 2015-08-17 2023-06-07 The Johns Hopkins University Fiber-hydrogel composite surgical meshes for tissue repair
CN108289734B (zh) 2015-08-17 2024-06-18 约翰·霍普金斯大学 用于组织恢复的间充质细胞结合复合材料
EP3337464B1 (en) 2015-08-17 2022-03-09 The Johns Hopkins University In situ forming composite material for tissue restoration

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