CA2975568A1 - Antibody-mediated disruption of quorum sensing in bacteria - Google Patents
Antibody-mediated disruption of quorum sensing in bacteria Download PDFInfo
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- CA2975568A1 CA2975568A1 CA2975568A CA2975568A CA2975568A1 CA 2975568 A1 CA2975568 A1 CA 2975568A1 CA 2975568 A CA2975568 A CA 2975568A CA 2975568 A CA2975568 A CA 2975568A CA 2975568 A1 CA2975568 A1 CA 2975568A1
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Classifications
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
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- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- A—HUMAN NECESSITIES
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
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- A—HUMAN NECESSITIES
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- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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| US60/982,593 | 2007-10-25 | ||
| CA2703133A CA2703133C (en) | 2007-10-25 | 2008-10-24 | Antibody-mediated disruption of quorum sensing in bacteria |
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| CA2703133A Division CA2703133C (en) | 2007-10-25 | 2008-10-24 | Antibody-mediated disruption of quorum sensing in bacteria |
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| CA2975568A1 true CA2975568A1 (en) | 2009-04-30 |
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| CA2975568A Abandoned CA2975568A1 (en) | 2007-10-25 | 2008-10-24 | Antibody-mediated disruption of quorum sensing in bacteria |
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| CA2703133A Active CA2703133C (en) | 2007-10-25 | 2008-10-24 | Antibody-mediated disruption of quorum sensing in bacteria |
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| US (2) | US9394371B2 (enExample) |
| EP (2) | EP2842565B1 (enExample) |
| JP (3) | JP5581490B2 (enExample) |
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| ES (1) | ES2603061T3 (enExample) |
| WO (1) | WO2009055054A2 (enExample) |
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| EP2911694A4 (en) | 2012-10-26 | 2016-07-13 | Sorrento Therapeutics Inc | ANTI-INFECTIOUS BINDING PROTEINS THAT BIND TO AIP2 |
| DE102013211850A1 (de) * | 2013-06-21 | 2014-12-24 | Gilupi Gmbh | Schnelltest zum Nachweisen von Erregermaterial, insbesondere zur Unterstützung der Diagnose einer Sepsis, sowie Kit und Vorrichtung zur Durchführung eines Sepsistests |
| NZ717476A (en) * | 2013-08-01 | 2022-04-29 | Univ Catholique Louvain | Anti-garp protein and uses thereof |
| CN105849087A (zh) | 2013-12-27 | 2016-08-10 | 诺华丝国际股份有限公司 | 乙氧基化表面活性剂 |
| KR102538555B1 (ko) | 2014-01-29 | 2023-05-30 | 케이엠 바이올로직스 가부시키가이샤 | 항-트랜스티레틴 인간화 항체 |
| EP3981874A1 (en) * | 2014-01-29 | 2022-04-13 | KM Biologics Co., Ltd. | Anti-transthyretin human antibody |
| WO2015119170A1 (ja) * | 2014-02-07 | 2015-08-13 | ミヤリサン製薬株式会社 | クロストリジウム属の菌の毒素産生抑制活性を有するペプチド |
| WO2017136400A1 (en) * | 2016-02-02 | 2017-08-10 | Stc. Unm | Vlp-based vaccines for targeting staphylococcus aureus secreted virulence factors |
| JP7058638B2 (ja) * | 2016-08-11 | 2022-04-22 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | ホスホグリセリン酸ムターゼのペプチド阻害剤および使用方法 |
| WO2018152452A1 (en) | 2017-02-17 | 2018-08-23 | Mapp Biopharmaceutical, Inc. | Monoclonal antibodies and cocktails for treatment of ebola infections |
| US10584306B2 (en) | 2017-08-11 | 2020-03-10 | Board Of Regents Of The University Of Oklahoma | Surfactant microemulsions |
| JP7373176B2 (ja) * | 2017-08-31 | 2023-11-02 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 皮膚の酵素活性を制御する分子的細菌療法 |
| EP3681903B1 (en) * | 2017-09-15 | 2023-07-19 | Lentigen Technology, Inc. | Compositions and methods for treating cancer with anti-cd19 immunotherapy |
| US10774135B2 (en) | 2017-12-22 | 2020-09-15 | Sorrento Therapeutics, Inc. | Variant antibodies that bind AIP2 |
| US11459445B2 (en) | 2018-02-13 | 2022-10-04 | Sumitomo Chemical Company, Limited | Composition and molded body |
| US11638759B2 (en) | 2019-08-13 | 2023-05-02 | Darlene E. McCord | Non-activated, amorphous, pH neutral, two-part bedside-ready clay delivery system that treats pathogen infections in humans and animals |
| CN111573853B (zh) * | 2020-05-29 | 2020-11-20 | 南京大学 | 一种削减生物法处理废水毒性的方法 |
| WO2023076855A1 (en) | 2021-10-25 | 2023-05-04 | Mccord Darlene E | Coated medicinal clay compositions, pharmaceutical compositions, and delivery of cation sources and methods of use thereof |
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| EP0932613B1 (en) * | 1996-05-22 | 2005-03-09 | New York University | Blocking expression of virulence factors in s. aureus |
| US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| WO2001085664A2 (en) * | 2000-05-10 | 2001-11-15 | Princeton University | Compounds and methods for regulating bacterial growth and pathogenesis |
| US7786257B2 (en) | 2000-12-18 | 2010-08-31 | University Of Kansas | Signal-1/signal-2 bifunctional peptide inhibitors |
| US6463632B2 (en) * | 2001-02-07 | 2002-10-15 | Hans Oetiker Ag Maschinen-Und Apparatefabrik | Guide arrangement for tightening tool emplacement in hose clamps provided with plastically deformable ears |
| CN1164612C (zh) * | 2001-09-11 | 2004-09-01 | 四川新泰克控股有限责任公司 | 人工组合的抗菌工程多肽及其制备方法 |
| CA2495725C (en) | 2002-08-13 | 2013-06-25 | Haptogen Ltd | Methods for the treatment of an infectious bacterial disease with an anti-lactone or lactone derived signal molecules antibody |
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2014
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2017
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2008317331B2 (en) | 2013-08-29 |
| EP2211889A4 (en) | 2012-01-11 |
| CN101835484B (zh) | 2014-07-16 |
| AU2008317331A1 (en) | 2009-04-30 |
| JP2014221774A (ja) | 2014-11-27 |
| WO2009055054A3 (en) | 2009-09-03 |
| JP2011500814A (ja) | 2011-01-06 |
| WO2009055054A2 (en) | 2009-04-30 |
| CN101835484A (zh) | 2010-09-15 |
| CA2703133C (en) | 2017-09-19 |
| CN104211775A (zh) | 2014-12-17 |
| US9394371B2 (en) | 2016-07-19 |
| EP2842565A1 (en) | 2015-03-04 |
| US20170043020A1 (en) | 2017-02-16 |
| JP2018021021A (ja) | 2018-02-08 |
| CA2703133A1 (en) | 2009-04-30 |
| KR101557173B1 (ko) | 2015-10-05 |
| KR20100102100A (ko) | 2010-09-20 |
| JP5581490B2 (ja) | 2014-09-03 |
| EP2211889B1 (en) | 2014-08-20 |
| JP6183910B2 (ja) | 2017-08-23 |
| ES2603061T3 (es) | 2017-02-23 |
| EP2842565B1 (en) | 2016-08-24 |
| EP2211889A2 (en) | 2010-08-04 |
| US20100291093A1 (en) | 2010-11-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20170802 |
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| FZDE | Discontinued |
Effective date: 20191024 |