CA2970140A1 - Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brain tumors - Google Patents
Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brain tumors Download PDFInfo
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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Landscapes
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| PCT/IB2015/002577 WO2016092378A1 (en) | 2014-12-10 | 2015-12-09 | Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brian tumors |
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| CA2970140A1 true CA2970140A1 (en) | 2016-06-16 |
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| US10852069B2 (en) | 2010-05-04 | 2020-12-01 | Fractal Heatsink Technologies, LLC | System and method for maintaining efficiency of a fractal heat sink |
| ES2796973T3 (es) * | 2014-12-10 | 2020-11-30 | Hyperstem Sa | Métodos y composiciones para reducir el crecimiento, la migración y la invasividad de células madre de cáncer cerebral y mejorar la supervivencia de pacientes con tumores cerebrales |
| CN111417403B (zh) * | 2017-10-25 | 2024-06-04 | 温特研究公司 | Wnt5a肽在减少癌症干细胞中的作用 |
| KR101921836B1 (ko) | 2017-11-23 | 2018-11-26 | 서울대학교병원 | 피부성체 줄기세포의 분화 조절 방법, 및 피부성체 줄기세포의 분화 조절용 조성물 및 키트 |
| WO2019207512A2 (en) * | 2018-04-24 | 2019-10-31 | Universidade Do Minho | A novel oncogene biomarker, method and uses thereof |
| EP3613757A1 (en) * | 2018-08-20 | 2020-02-26 | Wntresearch AB | Solution phase routes for wnt hexapeptides |
| EP3666789A1 (en) * | 2018-12-14 | 2020-06-17 | Wntresearch AB | Linear solution phase routes for wnt hexapeptides |
| CA3137093A1 (en) * | 2019-04-16 | 2020-10-22 | Wntresearch Ab | Peptides in combination with immune checkpoint inhibitors for use in treatment of cancer |
| WO2021034784A1 (en) | 2019-08-16 | 2021-02-25 | Poltorak Technologies, LLC | Device and method for medical diagnostics |
| CN114081954B (zh) * | 2021-10-30 | 2023-02-28 | 中国人民解放军陆军军医大学第一附属医院 | 用于胶质母细胞瘤治疗的药物组合物以及预后的诊断试剂 |
| WO2025088835A1 (ja) * | 2023-10-25 | 2025-05-01 | 国立大学法人大阪大学 | ヒト化抗ｃｋａｐ４抗体又はその抗原結合性断片 |
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| GB1521000A (en) | 1975-06-13 | 1978-08-09 | Syntex Puerto Rico Inc | Inhalation device |
| US4192309A (en) | 1978-09-05 | 1980-03-11 | Syntex Puerto Rico, Inc. | Inhalation device with capsule opener |
| US4227522A (en) | 1978-09-05 | 1980-10-14 | Syntex Puerto Rico, Inc. | Inhalation device |
| US4778054A (en) | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| ES286422Y (es) | 1982-10-08 | 1986-09-16 | Glaxo Group Limited | Dispositivo para administrar medicamentos a pacientes |
| AT396872B (de) | 1985-07-30 | 1993-12-27 | Glaxo Group Ltd | Gerät zur verabreichung von medikamenten in pulverform |
| JPH05963A (ja) | 1990-04-13 | 1993-01-08 | Toray Ind Inc | ポリペプチド類組成物 |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| EP1226172A1 (en) * | 1999-11-05 | 2002-07-31 | Forskarpatent i Syd AB | Compounds, antibodies and methods for treating, preventing or diagnosing tumour metastasis |
| DK2384763T3 (en) * | 2005-05-30 | 2015-07-20 | Wntres Ab | Peptide ligand for disrupting cancer cell migration |
| ES2527454T3 (es) * | 2008-08-13 | 2015-01-23 | Wntresearch Ab | El uso de derivados del péptido Wnt5-a para el tratamiento de melanoma y cáncer gástrico |
| AU2011205409B2 (en) * | 2010-01-12 | 2015-08-20 | Oncomed Pharmaceuticals, Inc. | Wnt-binding agents and uses thereof |
| EP2446895A1 (en) | 2010-10-01 | 2012-05-02 | Stemgen S.P.A. | EPH receptor expression in tumor stem cells |
| PL2726880T3 (pl) * | 2011-07-01 | 2019-09-30 | Wntresearch Ab | Leczenie nowotworu prostaty i sposób określania prognozy dla pacjentów z nowotworem prostaty |
| US20140171356A1 (en) | 2012-12-12 | 2014-06-19 | The Board Of Trustees Of The Leland Stanford Junior University | Chemically immobilized wnt protein and methods of use |
| ES2796973T3 (es) * | 2014-12-10 | 2020-11-30 | Hyperstem Sa | Métodos y composiciones para reducir el crecimiento, la migración y la invasividad de células madre de cáncer cerebral y mejorar la supervivencia de pacientes con tumores cerebrales |
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| EP3229831A1 (en) | 2017-10-18 |
| US10688167B2 (en) | 2020-06-23 |
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| US20170368158A1 (en) | 2017-12-28 |
| DK3229831T3 (da) | 2020-06-15 |
| KR20170098861A (ko) | 2017-08-30 |
| AU2015359043B2 (en) | 2021-09-02 |
| ES2796973T3 (es) | 2020-11-30 |
| US11357840B2 (en) | 2022-06-14 |
| AU2015359043A1 (en) | 2017-06-29 |
| HK1245152A1 (en) | 2018-08-24 |
| JP6921755B2 (ja) | 2021-08-18 |
| KR102674191B1 (ko) | 2024-06-11 |
| NZ732532A (en) | 2024-10-25 |
| AU2015359043C1 (en) | 2022-01-06 |
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