CA2962239C - Uses of trehalose in cell suspensions - Google Patents

Uses of trehalose in cell suspensions Download PDF

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Publication number
CA2962239C
CA2962239C CA2962239A CA2962239A CA2962239C CA 2962239 C CA2962239 C CA 2962239C CA 2962239 A CA2962239 A CA 2962239A CA 2962239 A CA2962239 A CA 2962239A CA 2962239 C CA2962239 C CA 2962239C
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CA
Canada
Prior art keywords
cells
trehalose
cell suspension
cell
thawed
Prior art date
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Active
Application number
CA2962239A
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English (en)
French (fr)
Other versions
CA2962239A1 (en
Inventor
Erik John Woods
Sreedhar Thirumala
Shelly J. Zacharias
Matthew B. Welty
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gallant Pet Inc
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Gallant Pet Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Gallant Pet Inc filed Critical Gallant Pet Inc
Publication of CA2962239A1 publication Critical patent/CA2962239A1/en
Application granted granted Critical
Publication of CA2962239C publication Critical patent/CA2962239C/en
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
CA2962239A 2014-09-29 2015-09-29 Uses of trehalose in cell suspensions Active CA2962239C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462056842P 2014-09-29 2014-09-29
US62/056,842 2014-09-29
PCT/US2015/052950 WO2016069173A2 (en) 2014-09-29 2015-09-29 Uses of trehalose in cell suspensions

Publications (2)

Publication Number Publication Date
CA2962239A1 CA2962239A1 (en) 2016-05-06
CA2962239C true CA2962239C (en) 2024-01-02

Family

ID=55583355

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2962239A Active CA2962239C (en) 2014-09-29 2015-09-29 Uses of trehalose in cell suspensions

Country Status (8)

Country Link
US (2) US20160089401A1 (https=)
EP (1) EP3201319A4 (https=)
JP (1) JP2017531446A (https=)
CN (1) CN107106488A (https=)
AU (1) AU2015339886B2 (https=)
BR (1) BR112017006533A2 (https=)
CA (1) CA2962239C (https=)
WO (1) WO2016069173A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190231694A1 (en) * 2016-10-12 2019-08-01 Agency For Science, Technology And Research Method for lyophilising an exosome
GB201716729D0 (en) * 2017-10-12 2017-11-29 Asymptote Ltd Cryopreservation method and apparatus
US11697799B2 (en) 2019-04-15 2023-07-11 Ossium Health, Inc. System and method for extraction and cryopreservation of bone marrow
AU2021267900A1 (en) 2020-05-08 2023-01-19 Gallant Pet Inc. Uterine-derived regenerative cell compositions and uses thereof
CN111638341A (zh) * 2020-07-01 2020-09-08 山东凯歌智能机器有限公司 一种检测小细胞肺癌患者外周血循环肿瘤细胞pd-l1基因突变的试剂盒及检测方法
CN111856022A (zh) * 2020-07-01 2020-10-30 山东凯歌智能机器有限公司 一种检测胰腺癌患者外周血循环肿瘤细胞E-Cadherin表达的试剂盒及检测方法
EP4181675A4 (en) 2020-07-18 2024-04-24 Ossium Health, Inc. PERMEATION OF WHOLE VERTEBRATE BODIES WITH A CRYOPRETECTIVE AGENT USING VACUUM-ASSISTED DIFFUSION
CA3195653A1 (en) 2020-10-14 2022-04-21 Ossium Health, Inc. Systems and methods for extraction and cryopreservation of bone marrow
WO2022133282A1 (en) 2020-12-18 2022-06-23 Ossium Health, Inc. Methods of cell therapies
KR20230157938A (ko) 2020-12-19 2023-11-17 하빌 에프 코라키왈라 동결건조 중간엽 줄기 세포

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69530196T2 (de) * 1994-06-02 2003-11-20 Elan Drug Delivery Ltd Methode zum verhindern der aggregation von proteinen/peptiden bei rehydratation oder auftauen
PT917879E (pt) * 1997-11-22 2002-12-31 Roche Diagnostics Gmbh Processo melhorado para estabilizacao de proteinas
CH700956B1 (de) * 2003-05-08 2010-11-15 Cellartis Ab Gefrierkonservierung menschlicher, von Blastocysten abgeleiteten Stammzellen nach dem Verfahren der Vitrifizierung im geschlossenen Röhrchen.
CA2595638A1 (en) * 2005-01-28 2006-08-03 Canadian Blood Services A method of cryopreserving cells and tissues by liposomal delivery of sugars to enhance post-thaw viability
KR20080087148A (ko) * 2006-01-04 2008-09-30 두-쿱 테크놀로지스 리미티드 저온보호 조성물 및 그 이용방법
KR20240052847A (ko) * 2008-08-20 2024-04-23 셀룰래리티 인코포레이티드 개선된 세포 조성물 및 그의 제조 방법
CN102625831A (zh) * 2009-07-20 2012-08-01 通用医院公司以麻省总医院名义经营 提高低温保存细胞生活力的方法和组合物
PT2611906T (pt) * 2010-08-31 2024-04-16 Gallant Pet Inc Terapias sistémicas com células estaminais alogénicas para tratamento de doenças em gatos e cães
JP5341059B2 (ja) * 2010-11-09 2013-11-13 株式会社大塚製薬工場 幹細胞懸濁液
JP6345123B2 (ja) * 2012-02-16 2018-06-20 サンタラス， インコーポレイテッド 抗ｖｌａ１（ｃｄ４９ａ）抗体医薬組成物
JP5432322B2 (ja) * 2012-05-08 2014-03-05 株式会社大塚製薬工場 トレハロース含有肺塞栓形成予防用哺乳動物細胞懸濁液
JP5196618B1 (ja) * 2012-09-28 2013-05-15 株式会社大塚製薬工場 トレハロース含有細胞洗浄溶液を用いた接着細胞の洗浄方法
CN104161037B (zh) * 2014-08-13 2016-01-13 江苏丘陵地区镇江农业科学研究所 一种山羊精液玻璃化冷冻和解冻配方与方法
CN105052894B (zh) * 2015-08-26 2018-03-06 中国农业科学院特产研究所 一种gv期卵母细胞冷冻保存液及冷冻保存方法

Also Published As

Publication number Publication date
US20160089401A1 (en) 2016-03-31
AU2015339886B2 (en) 2019-05-09
JP2017531446A (ja) 2017-10-26
WO2016069173A3 (en) 2016-07-28
BR112017006533A2 (pt) 2017-12-19
EP3201319A2 (en) 2017-08-09
WO2016069173A2 (en) 2016-05-06
AU2015339886A1 (en) 2017-04-13
CN107106488A (zh) 2017-08-29
EP3201319A4 (en) 2018-05-16
US20210252155A1 (en) 2021-08-19
CA2962239A1 (en) 2016-05-06

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