JP2017531446A - 細胞懸濁液中のトレハロースの使用 - Google Patents

細胞懸濁液中のトレハロースの使用 Download PDF

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Publication number
JP2017531446A
JP2017531446A JP2017536231A JP2017536231A JP2017531446A JP 2017531446 A JP2017531446 A JP 2017531446A JP 2017536231 A JP2017536231 A JP 2017536231A JP 2017536231 A JP2017536231 A JP 2017536231A JP 2017531446 A JP2017531446 A JP 2017531446A
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Prior art keywords
cell
trehalose
cells
composition
aqueous medium
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JP2017536231A
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Japanese (ja)
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JP2017531446A5 (https=
Inventor
エリク， ジョン ウッズ，
エリク， ジョン ウッズ，
スレッド ティルバナ，
スレッド ティルバナ，
シェリー， ジェイ． ザカリアス，
シェリー， ジェイ． ザカリアス，
マシュー， ビー ウェルティー，
マシュー， ビー ウェルティー，
Original Assignee
クック・ジェネラル・バイオテクノロジー・エルエルシー
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Publication of JP2017531446A publication Critical patent/JP2017531446A/ja
Publication of JP2017531446A5 publication Critical patent/JP2017531446A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
JP2017536231A 2014-09-29 2015-09-29 細胞懸濁液中のトレハロースの使用 Pending JP2017531446A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462056842P 2014-09-29 2014-09-29
US62/056,842 2014-09-29
PCT/US2015/052950 WO2016069173A2 (en) 2014-09-29 2015-09-29 Uses of trehalose in cell suspensions

Publications (2)

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JP2017531446A true JP2017531446A (ja) 2017-10-26
JP2017531446A5 JP2017531446A5 (https=) 2018-11-08

Family

ID=55583355

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017536231A Pending JP2017531446A (ja) 2014-09-29 2015-09-29 細胞懸濁液中のトレハロースの使用

Country Status (8)

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US (2) US20160089401A1 (https=)
EP (1) EP3201319A4 (https=)
JP (1) JP2017531446A (https=)
CN (1) CN107106488A (https=)
AU (1) AU2015339886B2 (https=)
BR (1) BR112017006533A2 (https=)
CA (1) CA2962239C (https=)
WO (1) WO2016069173A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12497594B2 (en) 2020-05-08 2025-12-16 Gallant Pet, Inc. Uterine-derived regenerative cell compositions and uses thereof

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US20190231694A1 (en) * 2016-10-12 2019-08-01 Agency For Science, Technology And Research Method for lyophilising an exosome
GB201716729D0 (en) * 2017-10-12 2017-11-29 Asymptote Ltd Cryopreservation method and apparatus
US11697799B2 (en) 2019-04-15 2023-07-11 Ossium Health, Inc. System and method for extraction and cryopreservation of bone marrow
CN111638341A (zh) * 2020-07-01 2020-09-08 山东凯歌智能机器有限公司 一种检测小细胞肺癌患者外周血循环肿瘤细胞pd-l1基因突变的试剂盒及检测方法
CN111856022A (zh) * 2020-07-01 2020-10-30 山东凯歌智能机器有限公司 一种检测胰腺癌患者外周血循环肿瘤细胞E-Cadherin表达的试剂盒及检测方法
EP4181675A4 (en) 2020-07-18 2024-04-24 Ossium Health, Inc. PERMEATION OF WHOLE VERTEBRATE BODIES WITH A CRYOPRETECTIVE AGENT USING VACUUM-ASSISTED DIFFUSION
CA3195653A1 (en) 2020-10-14 2022-04-21 Ossium Health, Inc. Systems and methods for extraction and cryopreservation of bone marrow
WO2022133282A1 (en) 2020-12-18 2022-06-23 Ossium Health, Inc. Methods of cell therapies
KR20230157938A (ko) 2020-12-19 2023-11-17 하빌 에프 코라키왈라 동결건조 중간엽 줄기 세포

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012500021A (ja) * 2008-08-20 2012-01-05 アンスロジェネシス コーポレーション 改良型細胞組成物およびその作製方法
JP2012115253A (ja) * 2010-11-09 2012-06-21 Otsuka Pharmaceut Factory Inc 幹細胞懸濁液
JP2013233102A (ja) * 2012-05-08 2013-11-21 Otsuka Pharmaceut Factory Inc トレハロース含有肺塞栓形成予防用哺乳動物細胞懸濁液

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DE69530196T2 (de) * 1994-06-02 2003-11-20 Elan Drug Delivery Ltd Methode zum verhindern der aggregation von proteinen/peptiden bei rehydratation oder auftauen
PT917879E (pt) * 1997-11-22 2002-12-31 Roche Diagnostics Gmbh Processo melhorado para estabilizacao de proteinas
CH700956B1 (de) * 2003-05-08 2010-11-15 Cellartis Ab Gefrierkonservierung menschlicher, von Blastocysten abgeleiteten Stammzellen nach dem Verfahren der Vitrifizierung im geschlossenen Röhrchen.
CA2595638A1 (en) * 2005-01-28 2006-08-03 Canadian Blood Services A method of cryopreserving cells and tissues by liposomal delivery of sugars to enhance post-thaw viability
KR20080087148A (ko) * 2006-01-04 2008-09-30 두-쿱 테크놀로지스 리미티드 저온보호 조성물 및 그 이용방법
CN102625831A (zh) * 2009-07-20 2012-08-01 通用医院公司以麻省总医院名义经营 提高低温保存细胞生活力的方法和组合物
PT2611906T (pt) * 2010-08-31 2024-04-16 Gallant Pet Inc Terapias sistémicas com células estaminais alogénicas para tratamento de doenças em gatos e cães
JP6345123B2 (ja) * 2012-02-16 2018-06-20 サンタラス， インコーポレイテッド 抗ｖｌａ１（ｃｄ４９ａ）抗体医薬組成物
JP5196618B1 (ja) * 2012-09-28 2013-05-15 株式会社大塚製薬工場 トレハロース含有細胞洗浄溶液を用いた接着細胞の洗浄方法
CN104161037B (zh) * 2014-08-13 2016-01-13 江苏丘陵地区镇江农业科学研究所 一种山羊精液玻璃化冷冻和解冻配方与方法
CN105052894B (zh) * 2015-08-26 2018-03-06 中国农业科学院特产研究所 一种gv期卵母细胞冷冻保存液及冷冻保存方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012500021A (ja) * 2008-08-20 2012-01-05 アンスロジェネシス コーポレーション 改良型細胞組成物およびその作製方法
JP2012115253A (ja) * 2010-11-09 2012-06-21 Otsuka Pharmaceut Factory Inc 幹細胞懸濁液
JP2013233102A (ja) * 2012-05-08 2013-11-21 Otsuka Pharmaceut Factory Inc トレハロース含有肺塞栓形成予防用哺乳動物細胞懸濁液

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12497594B2 (en) 2020-05-08 2025-12-16 Gallant Pet, Inc. Uterine-derived regenerative cell compositions and uses thereof

Also Published As

Publication number Publication date
US20160089401A1 (en) 2016-03-31
AU2015339886B2 (en) 2019-05-09
CA2962239C (en) 2024-01-02
WO2016069173A3 (en) 2016-07-28
BR112017006533A2 (pt) 2017-12-19
EP3201319A2 (en) 2017-08-09
WO2016069173A2 (en) 2016-05-06
AU2015339886A1 (en) 2017-04-13
CN107106488A (zh) 2017-08-29
EP3201319A4 (en) 2018-05-16
US20210252155A1 (en) 2021-08-19
CA2962239A1 (en) 2016-05-06

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