CA2945414C - Method of isolating a target cell - Google Patents
Method of isolating a target cell Download PDFInfo
- Publication number
- CA2945414C CA2945414C CA2945414A CA2945414A CA2945414C CA 2945414 C CA2945414 C CA 2945414C CA 2945414 A CA2945414 A CA 2945414A CA 2945414 A CA2945414 A CA 2945414A CA 2945414 C CA2945414 C CA 2945414C
- Authority
- CA
- Canada
- Prior art keywords
- binding
- reagent
- ligand
- streptavidin
- receptor molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
Landscapes
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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| EP14166718.8 | 2014-04-30 | ||
| PCT/EP2015/059510 WO2015166049A1 (en) | 2014-04-30 | 2015-04-30 | Method of isolating a target cell |
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| CA2945414A1 CA2945414A1 (en) | 2015-11-05 |
| CA2945414C true CA2945414C (en) | 2023-05-09 |
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| SG10201606970UA (en) | 2012-02-23 | 2016-10-28 | Juno Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
| SG11201608557UA (en) * | 2014-04-16 | 2016-11-29 | Juno Therapeutics Gmbh | Methods, kits and apparatus for expanding a population of cells |
| MA45488A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés, kits et appareil de culture de cellules |
| RU2761555C2 (ru) | 2015-10-22 | 2021-12-09 | Джуно Терапьютикс Гмбх | Способы, наборы, средства и устройства для трансдукции |
| MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
| CN111032850B (zh) | 2017-04-27 | 2024-08-13 | 朱诺治疗学有限公司 | 寡聚粒子试剂及其使用方法 |
| KR102088277B1 (ko) * | 2018-04-27 | 2020-03-13 | 주식회사 유니언스진 | 면역 화학 진단법을 이용한 표적 항원 검출용 종이기반 3차원 구조의 미세칩과 이를 이용한 표적항원 검출 방법 |
| WO2019226529A1 (en) * | 2018-05-21 | 2019-11-28 | Bioprocessia Technologies Llc | Multivalent protein complexes |
| JP2021530230A (ja) * | 2018-07-17 | 2021-11-11 | ユニヴァーシティ オブ ワシントン | アプタマーベースの可逆的細胞選択に関連する組成物および方法 |
| EP3833742A2 (en) | 2018-08-09 | 2021-06-16 | Juno Therapeutics, Inc. | Processes for generating engineered cells and compositions thereof |
| EP3844478A4 (en) * | 2018-08-31 | 2022-05-18 | ThermoGenesis Corp. | METHODS OF ISOLATING TARGET CELLS FROM BLOOD |
| CN113227358A (zh) | 2018-10-31 | 2021-08-06 | 朱诺治疗学有限公司 | 选择并刺激细胞的方法及用于所述方法的设备 |
| JP7502451B2 (ja) * | 2020-01-31 | 2024-06-18 | セル．コペディア ゲーエムベーハー | 生物学的実体を単離する方法 |
| WO2023017115A1 (en) | 2021-08-11 | 2023-02-16 | Iba Lifesciences Gmbh | Fractionation of cells based on a marker protein |
| CA3256271A1 (en) | 2022-04-28 | 2023-11-02 | Bio-Recell Ltd. | TARGET CELL SEPARATION PROCESS |
| WO2025238197A1 (en) * | 2024-05-16 | 2025-11-20 | Iba Lifesciences Gmbh | Functionalized three-dimensional (3d) polymer scaffold for affinity chromatography |
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| DE3583940D1 (de) | 1984-10-02 | 1991-10-02 | Harry M Meade | Herstellung von streptavidinaehnlichen polypeptiden. |
| US4851341A (en) | 1986-12-19 | 1989-07-25 | Immunex Corporation | Immunoaffinity purification system |
| DE4237113B4 (de) | 1992-11-03 | 2006-10-12 | "Iba Gmbh" | Peptide und deren Fusionsproteine, Expressionsvektor und Verfahren zur Herstellung eines Fusionsproteins |
| WO1996023879A1 (en) | 1995-01-30 | 1996-08-08 | Terrapin Technologies, Inc. | Glubodies - multiplicities of proteins capable of binding a variety of small molecules |
| JPH11501008A (ja) | 1995-02-09 | 1999-01-26 | ユニバーシティ オブ ワシントン | 改変−アフィニティーストレプトアビジン |
| EP0856055A1 (en) | 1995-04-11 | 1998-08-05 | Trustees Of Boston University | Streptavidin mutants |
| DE19641876B4 (de) | 1996-10-10 | 2011-09-29 | Iba Gmbh | Streptavidinmuteine |
| WO1998040396A1 (en) | 1997-03-14 | 1998-09-17 | Trustees Of Boston University | Multiflavor streptavidin |
| US5985658A (en) | 1997-11-14 | 1999-11-16 | Health Research Incorporated | Calmodulin-based cell separation technique |
| DE19932688B4 (de) | 1999-07-13 | 2009-10-08 | Scil Proteins Gmbh | Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen |
| EP1227321A1 (en) | 2000-12-28 | 2002-07-31 | Institut für Bioanalytik GmbH | Reversible MHC multimer staining for functional purification of antigen-specific T cells |
| DE10113776B4 (de) | 2001-03-21 | 2012-08-09 | "Iba Gmbh" | Isoliertes streptavidinbindendes, kompetitiv eluierbares Peptid, dieses umfassendes Fusionspeptid, dafür codierende Nukleinsäure, Expressionsvektor, Verfahren zur Herstellung eines rekombinanten Fusionsproteins und Verfahren zum Nachweis und/oder zur Gewinnung des Fusionsproteins |
| WO2003029462A1 (en) | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of human neutrophil gelatinase-associated lipocalin and related proteins |
| WO2006115129A1 (ja) | 2005-04-19 | 2006-11-02 | Matsushita Electric Industrial Co., Ltd. | 位置センサ、光ヘッド装置、ヘッド移動機構、情報記録再生装置、および位置制御システム |
| CN101622340A (zh) * | 2006-11-15 | 2010-01-06 | 茵维特罗根戴纳股份公司 | 生物素化合物与支持物可逆结合的方法 |
| US8008032B2 (en) * | 2008-02-25 | 2011-08-30 | Cellective Dx Corporation | Tagged ligands for enrichment of rare analytes from a mixed sample |
| US10023657B2 (en) * | 2010-10-01 | 2018-07-17 | Ludwig Institute For Cancer Research Ltd. | Reversible protein multimers, methods for their production and use |
| ES2682750T5 (en) | 2011-07-18 | 2025-02-04 | Iba Lifesciences Gmbh | Method of reversibly staining a target cell |
| SG10201606970UA (en) | 2012-02-23 | 2016-10-28 | Juno Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
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2015
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- 2015-04-30 CN CN201580035819.4A patent/CN106662584B/zh active Active
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- 2015-04-30 AU AU2015254588A patent/AU2015254588B2/en active Active
- 2015-04-30 CA CA2945414A patent/CA2945414C/en active Active
- 2015-04-30 WO PCT/EP2015/059510 patent/WO2015166049A1/en not_active Ceased
- 2015-04-30 US US15/306,995 patent/US11150239B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN106662584A (zh) | 2017-05-10 |
| EP3137905B1 (en) | 2021-01-13 |
| WO2015166049A1 (en) | 2015-11-05 |
| US11150239B2 (en) | 2021-10-19 |
| US20170052176A1 (en) | 2017-02-23 |
| AU2015254588B2 (en) | 2020-05-21 |
| CN106662584B (zh) | 2020-05-05 |
| CA2945414A1 (en) | 2015-11-05 |
| JP2017514481A (ja) | 2017-06-08 |
| AU2015254588A1 (en) | 2016-11-10 |
| EP3137905A1 (en) | 2017-03-08 |
| JP6678593B2 (ja) | 2020-04-08 |
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| CA2945414C (en) | Method of isolating a target cell | |
| AU2021282451B2 (en) | Chromatographic isolation of cells and other complex biological materials | |
| CA3163761C (en) | Methods of isolating a biological entity | |
| HK1202335B (en) | Chromatographic isolation of cells and other complex biological materials |
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