CA2934199A1 - Urea derivatives useful as kinase inhibitors - Google Patents

Urea derivatives useful as kinase inhibitors Download PDF

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Publication number
CA2934199A1
CA2934199A1 CA2934199A CA2934199A CA2934199A1 CA 2934199 A1 CA2934199 A1 CA 2934199A1 CA 2934199 A CA2934199 A CA 2934199A CA 2934199 A CA2934199 A CA 2934199A CA 2934199 A1 CA2934199 A1 CA 2934199A1
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CA
Canada
Prior art keywords
tert
naphthalen
oxy
butyl
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2934199A
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English (en)
French (fr)
Inventor
Matthew Colin Thor Fyfe
Stephen Malcolm THOM
Thomas Matthew Baker
Gareth William Harbottle
Vedran Hasimbegovic
Aaron Rigby
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TopiVert Pharma Ltd
Original Assignee
Respivert Ltd
TopiVert Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority claimed from GBGB1322672.5A external-priority patent/GB201322672D0/en
Priority claimed from GB201416430A external-priority patent/GB201416430D0/en
Application filed by Respivert Ltd, TopiVert Pharma Ltd filed Critical Respivert Ltd
Publication of CA2934199A1 publication Critical patent/CA2934199A1/en
Abandoned legal-status Critical Current

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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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