CA2933065C - Materials and methods for controlling infections - Google Patents

Materials and methods for controlling infections Download PDF

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Publication number
CA2933065C
CA2933065C CA2933065A CA2933065A CA2933065C CA 2933065 C CA2933065 C CA 2933065C CA 2933065 A CA2933065 A CA 2933065A CA 2933065 A CA2933065 A CA 2933065A CA 2933065 C CA2933065 C CA 2933065C
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CA
Canada
Prior art keywords
chlorhexidine
solution
site
active agent
disinfectant composition
Prior art date
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Application number
CA2933065A
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English (en)
French (fr)
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CA2933065A1 (en
Inventor
Carolyn L. Twomey
Gareth Clarke
Samuel J. Zaidspiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innovation Technologies Inc
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Innovation Technologies Inc
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Publication of CA2933065A1 publication Critical patent/CA2933065A1/en
Application granted granted Critical
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/15Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/00051Accessories for dressings
    • A61F13/00063Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/191Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0085Brain, e.g. brain implants; Spinal cord
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/005Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0017Catheters; Hollow probes specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A61L2300/206Biguanides, e.g. chlorohexidine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CA2933065A 2013-12-12 2014-12-12 Materials and methods for controlling infections Active CA2933065C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361915281P 2013-12-12 2013-12-12
US61/915,281 2013-12-12
PCT/US2014/070059 WO2015089421A1 (en) 2013-12-12 2014-12-12 Materials and methods for controlling infections

Publications (2)

Publication Number Publication Date
CA2933065A1 CA2933065A1 (en) 2015-06-18
CA2933065C true CA2933065C (en) 2021-08-24

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2933065A Active CA2933065C (en) 2013-12-12 2014-12-12 Materials and methods for controlling infections

Country Status (15)

Country Link
US (9) US9642820B2 (OSRAM)
EP (1) EP3079681B1 (OSRAM)
JP (2) JP2017503852A (OSRAM)
KR (1) KR20160096678A (OSRAM)
CN (1) CN105979940A (OSRAM)
AU (2) AU2014361828A1 (OSRAM)
BR (1) BR112016013199A2 (OSRAM)
CA (1) CA2933065C (OSRAM)
CL (1) CL2016001447A1 (OSRAM)
IL (1) IL246087A0 (OSRAM)
MX (1) MX388424B (OSRAM)
PH (1) PH12016501099A1 (OSRAM)
RU (1) RU2682642C1 (OSRAM)
SG (2) SG10201811454WA (OSRAM)
WO (1) WO2015089421A1 (OSRAM)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0808376D0 (en) 2008-05-08 2008-06-18 Bristol Myers Squibb Co Wound dressing
GB0817796D0 (en) 2008-09-29 2008-11-05 Convatec Inc wound dressing
GB201020236D0 (en) 2010-11-30 2011-01-12 Convatec Technologies Inc A composition for detecting biofilms on viable tissues
DK2648795T3 (da) 2010-12-08 2023-03-27 Convatec Technologies Inc System til fjernelse af eksudater fra en sårposition
CN103347562B (zh) 2010-12-08 2016-08-10 康沃特克科技公司 伤口分泌液系统附件
CA2819475C (en) 2010-12-08 2019-02-12 Convatec Technologies Inc. Integrated system for assessing wound exudates
GB201115182D0 (en) 2011-09-02 2011-10-19 Trio Healthcare Ltd Skin contact material
GB2497406A (en) 2011-11-29 2013-06-12 Webtec Converting Llc Dressing with a perforated binder layer
GB201120693D0 (en) 2011-12-01 2012-01-11 Convatec Technologies Inc Wound dressing for use in vacuum therapy
MX2015007771A (es) 2012-12-20 2015-09-04 Convatec Technologies Inc Procesamiento de fibras celulosicas quimicamente modificadas.
CN105979940A (zh) 2013-12-12 2016-09-28 创新技术股份有限公司 控制感染的材料和方法
US10016375B2 (en) 2013-12-12 2018-07-10 Paul J. Rucinski Materials and methods for controlling infections
US9848604B2 (en) * 2014-07-11 2017-12-26 Medtronic Xomed, Inc. Antimicrobial wash
EP3177333A4 (en) * 2014-08-08 2018-04-04 Innovation Technologies, Inc. Materials and methods for controlling infections with negative pressure wound therapy
GB2543544A (en) 2015-10-21 2017-04-26 Brightwake Ltd Wound dressing
JP7183146B2 (ja) 2016-03-30 2022-12-05 コンバテック・テクノロジーズ・インコーポレイテッド 創傷における微生物感染の検出
JP2019513238A (ja) 2016-03-30 2019-05-23 クオリザイム・ダイアグノスティクス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング・ウント・コムパニー・コマンディットゲゼルシャフトQualizyme Diagnostics Gmbh And Co. Kg 創傷における微生物感染の検出
CA3022983C (en) * 2016-05-06 2024-05-07 SaCSh Corp. Ophthalmic compositions comprising chlorhexidine and an anti-inflammatory agent
GB201608099D0 (en) 2016-05-09 2016-06-22 Convatec Technologies Inc Negative pressure wound dressing
DK3481360T3 (da) 2016-07-08 2022-03-28 Convatec Technologies Inc Fluidstrømningsmåling
KR20190026858A (ko) 2016-07-08 2019-03-13 컨바텍 테크놀러지스 인크 가요성 부압 시스템
BR112019000284A2 (pt) 2016-07-08 2019-04-16 Convatec Technologies Inc. aparelho de coleta de fluido
EP3532043A4 (en) * 2016-10-26 2020-09-09 Innovation Technologies, Inc. MATERIALS AND METHODS OF CONTROLLING A BIOFILM
CA3073325A1 (en) * 2017-08-25 2019-02-28 AZ Solutions LLC System and method for wound treatment and irrigation
US11045589B2 (en) 2017-09-22 2021-06-29 Becton, Dickinson And Company 4% trisodium citrate solution for use as a catheter lock solution
US20190117569A1 (en) * 2017-10-24 2019-04-25 Saint Anthony Biomedical, LLC Compositions and methods for reducing infection in wounds and surgical sites
EP3710074B1 (en) 2017-11-16 2024-03-20 ConvaTec Limited Fluid collection apparatus
WO2020005785A1 (en) * 2018-06-26 2020-01-02 Innovation Technologies, Inc. Pyrogen binding composition and use of same in treatment and prevention of sepsis
EP3962544B1 (en) 2019-06-03 2023-11-08 Convatec Limited Methods and devices to disrupt and contain pathogens
US11771819B2 (en) 2019-12-27 2023-10-03 Convatec Limited Low profile filter devices suitable for use in negative pressure wound therapy systems
US11331221B2 (en) 2019-12-27 2022-05-17 Convatec Limited Negative pressure wound dressing
CN112294789B (zh) * 2020-10-15 2022-06-07 郑涛 用于防治呼吸道感染的复方制剂及其应用
EP4247352A1 (en) * 2020-11-18 2023-09-27 Institut Curie Dimers of biguanidines and their therapeutic uses
US11722993B2 (en) * 2021-03-23 2023-08-08 Qualcomm Incorporated Techniques for configuring resources in a sidelink resource pool
US11951087B2 (en) 2021-07-27 2024-04-09 Lanny Leo Johnson Eye wash compositions and methods
US20250282811A1 (en) * 2021-10-02 2025-09-11 Desert King Chile S.A A 3-o-monodesmosidic saponins extract, stable at physiological ph, method for preparing it from a quillaja plant extract cultured with a microbial consortium, uses and such microbial consortium

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2090354A (en) * 1936-05-14 1937-08-17 Abraham E Massman Combined medicine dropper and swab
US4299221A (en) * 1979-09-28 1981-11-10 Stryker Corporation Irrigation and suction handpiece
US4704102A (en) * 1982-09-30 1987-11-03 Geneco Inc. Method of eliminating intra abdominal infections
US5002769A (en) * 1987-03-13 1991-03-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions for the sustained-release of chlorhexidine
IE883722L (en) * 1988-12-14 1990-06-14 Galway Dental Technology Ltd Fluid dispenser for the treatment of a dental disorder
US4925668A (en) * 1989-01-18 1990-05-15 Becton, Dickinson And Company Anti-infective and lubricious medical articles and method for their preparation
US5002528A (en) * 1989-12-15 1991-03-26 Aubrey Palestrant Percutaneous irrigation and drainage system
US5333603A (en) * 1992-02-25 1994-08-02 Daniel Schuman Endoscope with palm rest
US6558686B1 (en) 1995-11-08 2003-05-06 Baylor College Of Medicine Method of coating medical devices with a combination of antiseptics and antiseptic coating therefor
JPH09301858A (ja) * 1996-05-13 1997-11-25 Senju Pharmaceut Co Ltd グルコン酸クロルヘキシジン安定化水性薬剤
US5725311A (en) 1996-07-19 1998-03-10 Sage Products, Inc. Resealable package with label peeling inhibiting means
JP3054758B2 (ja) * 1997-03-27 2000-06-19 小林製薬株式会社 外傷用組成物
US5906278A (en) 1997-10-06 1999-05-25 Sage Products, Inc. Patient bathing system
US5956794A (en) 1997-10-31 1999-09-28 Sage Products, Inc. Patient bathing system and washcloth for body cleansing
RU2166314C2 (ru) * 1999-07-06 2001-05-10 Открытое акционерное общество "Нижегородский химико-фармацевтический завод" Лечебно-профилактическое средство "гексикон", обладающее антибактериальным и антисептическим действием
US7066932B1 (en) * 2001-05-26 2006-06-27 Map Technologies Llc Biologically enhanced irrigants
US6964653B2 (en) * 2002-02-06 2005-11-15 Felipe Negron Multi-use hygienic cleansing device
US7066916B2 (en) 2003-05-12 2006-06-27 Sage Products, Inc. Disinfectant delivery system, and method of providing alcohol-free disinfection
RU2240821C1 (ru) * 2003-06-02 2004-11-27 Научно-исследовательский институт вакцин и сывороток им. И.И.Мечникова РАМН Способ лечения урогенитальных инфекций
IL156945A0 (en) * 2003-07-15 2004-02-08 Itzhak Tavori Device and a method for orthopedic delivery of bone reconstruction medium
KR101158954B1 (ko) 2003-09-22 2012-06-21 이노베이션 테크놀로지스, 인코포레이티드 상처 세척 장치 및 방법
US20050191247A1 (en) 2004-03-01 2005-09-01 David Drake Chlorhexidine compositions
WO2007003028A1 (en) * 2005-07-01 2007-01-11 Kane Biotech Inc. Antimicrobial compositions for inhibiting growth and proliferation of a microbial biofilm on medical devices
US20080139450A1 (en) * 2005-07-01 2008-06-12 Srinivasa Madhyastha Antimicrobial Compositions and Uses Thereof
WO2008060380A2 (en) * 2006-10-18 2008-05-22 Arrow International, Inc. Anti-infective alcohol catheter solution with chlorhexidine treated catheter
US20110097372A1 (en) * 2009-10-26 2011-04-28 Rucinski Paul J Devices, methods, and compositions for controlling infections
WO2013033159A1 (en) * 2011-08-31 2013-03-07 The Trustees Of Columbia University In The City Of New York Reduction of biofilms on medical devices
GB0716605D0 (en) 2007-08-24 2007-10-03 Univ Aston Skin antiseptics
US8696820B2 (en) * 2008-03-31 2014-04-15 Bard Access Systems, Inc. Method of removing a biofilm from a surface
CN102056600A (zh) * 2008-04-07 2011-05-11 界面生物公司 用于治疗细菌感染的组合疗法
WO2010014676A1 (en) * 2008-08-01 2010-02-04 Ondine International Ltd. Composition and method for treatment of mrsa
US8622996B2 (en) * 2008-10-27 2014-01-07 Pursuit Vascular, Inc. Method for applying antimicrobial to proximal end of catheter
RU2455037C2 (ru) * 2009-05-14 2012-07-10 Государственное образовательное учреждение высшего профессионального образования "Челябинская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию" Способ локальной иммунокоррекции инфекционно-воспалительных заболеваний урогенитального тракта женщин, вызванных микроорганизмами, передаваемыми половым путём
JP5639345B2 (ja) * 2009-05-27 2014-12-10 花王株式会社 バイオフィルム除去剤組成物
RU2404430C1 (ru) * 2009-07-27 2010-11-20 Ирина Дмитриевна Евтушенко Способ диагностики атрофии влагалища у женщин репродуктивного возраста в состоянии постовариоэктомии
EP2493442A4 (en) * 2009-10-26 2013-05-15 Innovation Technologies Inc DEVICES, METHODS AND COMPOSITION FOR COMBATING INFECTIONS
US8343525B2 (en) 2009-12-22 2013-01-01 Becton, Dickinson And Company Chlorhexidine acetate antiseptic cleaning agent
JP2013532716A (ja) * 2010-08-05 2013-08-19 ヘルパービー セラピューティクス リミテッド ピロロキノリン化合物と、β−ラクタム系抗微生物剤、ムピロシンまたはクロルヘキシジンとの組み合わせ
US8529546B2 (en) * 2010-10-21 2013-09-10 John J. Martinez Sinusal guide cannula and kit for irrigation, suction and washing
US20120150131A1 (en) 2010-12-09 2012-06-14 Teleflex Medical Incorporated Polymer for Controlling Delivery of Bioactive Agents and Method of Use
US9327095B2 (en) * 2013-03-11 2016-05-03 Becton, Dickinson And Company Blood control catheter with antimicrobial needle lube
CN103211805A (zh) * 2013-04-18 2013-07-24 江苏健裕健康医疗器械有限公司 洗必泰葡萄糖酸盐复合消毒液
US9345414B1 (en) 2013-09-25 2016-05-24 Bardy Diagnostics, Inc. Method for providing dynamic gain over electrocardiographic data with the aid of a digital computer
CN105979940A (zh) 2013-12-12 2016-09-28 创新技术股份有限公司 控制感染的材料和方法

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