CA2927334C - Pellicule pharmaceutique soluble dans l'eau presentant une stabilite amelioree - Google Patents
Pellicule pharmaceutique soluble dans l'eau presentant une stabilite amelioree Download PDFInfo
- Publication number
- CA2927334C CA2927334C CA2927334A CA2927334A CA2927334C CA 2927334 C CA2927334 C CA 2927334C CA 2927334 A CA2927334 A CA 2927334A CA 2927334 A CA2927334 A CA 2927334A CA 2927334 C CA2927334 C CA 2927334C
- Authority
- CA
- Canada
- Prior art keywords
- film
- moisture
- drying
- range
- water soluble
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
Abstract
La présente invention concerne une pellicule mince orale qui est instantanément mouillable, se dissout rapidement, et est non collante, non poisseuse et non incurvée. Ladite pellicule est apte à comporter un principe actif à administrer par voie orale sous la forme d'une pellicule stabilisée humide qui reste non collante et non incurvée lorsqu'elle est exposée à 70 ± 5 % de HR (humidité relative) à 25°C, pendant au moins 2 minutes et jusqu'à 2 heures, dans des conditions ouvertes sans emballage.L'invention porte également sur un procédé de réalisation de ladite pellicule. Le principe actif peut comprendre, sans limite, un principe actif cosmaceutique, nutraceutique ou pharmaceutique. Ledit procédé comprend les étapes suivantes : (a) séchage d'une pellicule moulée en deux étapes ou davantage; (b) séchage de la pellicule après moulage, alternativement sur les deux côtés; (c) revêtement de la pellicule séchée avec des polymères hydrophobes anti-humidité, résistants à l'humidité, synthétiques, insolubles dans l'eau et ne fondant pas à haute température; et (d) ajout d'un polymère hydrophobe anti-humidité, résistant à l'humidité, synthétique, insoluble dans l'eau, et ne fondant pas à température élevée, à la solution devant être moulée en tant que pellicule.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN3221/MUM/2013 | 2013-10-14 | ||
IN3221MU2013 IN2013MU03221A (fr) | 2013-10-14 | 2014-10-13 | |
PCT/IN2014/000652 WO2015083181A2 (fr) | 2013-10-14 | 2014-10-13 | Pellicule pharmaceutique soluble dans l'eau présentant une stabilité améliorée |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2927334A1 CA2927334A1 (fr) | 2015-06-11 |
CA2927334C true CA2927334C (fr) | 2023-08-29 |
Family
ID=53274239
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2927334A Active CA2927334C (fr) | 2013-10-14 | 2014-10-13 | Pellicule pharmaceutique soluble dans l'eau presentant une stabilite amelioree |
Country Status (8)
Country | Link |
---|---|
BR (1) | BR112016008356B1 (fr) |
CA (1) | CA2927334C (fr) |
CL (1) | CL2016000880A1 (fr) |
EA (1) | EA038558B1 (fr) |
IN (1) | IN2013MU03221A (fr) |
MY (1) | MY184297A (fr) |
UA (1) | UA123893C2 (fr) |
WO (1) | WO2015083181A2 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10660862B2 (en) * | 2013-12-17 | 2020-05-26 | Zim Laboratories Limited | Pharmaceutical microemulsion immobilized in a thin polymer matrix and methods of making them |
KR20190128637A (ko) * | 2017-03-30 | 2019-11-18 | 인텔젠스 코프. | 류코트리엔 수용체 길항제의 개선된 생체이용률을 위한 치료방법 및 장치 |
FR3082851B1 (fr) * | 2018-06-25 | 2022-09-02 | Biomerieux Sa | Procede de detection et/ou d'identification d'au moins un microorganisme cible present sur une surface. |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5947987B2 (ja) * | 1979-10-08 | 1984-11-22 | 富士写真フイルム株式会社 | 加筆・修正可能なマツトフイルム |
US4664859A (en) * | 1983-12-02 | 1987-05-12 | Vcf Films Inc. Div. Of Pmc | Process for solvent casting a film |
US5272191A (en) * | 1991-08-21 | 1993-12-21 | Fmc Corporation | Cold water soluble films and film forming compositions |
US6966960B2 (en) * | 2003-05-07 | 2005-11-22 | Hewlett-Packard Development Company, L.P. | Fusible water-soluble films for fabricating three-dimensional objects |
WO2005084636A2 (fr) * | 2004-02-27 | 2005-09-15 | Ranbaxy Laboratories Limited | Procede de preparation d'une composition pharmaceutique a liberation controlee de metoprolol |
KR100705210B1 (ko) * | 2004-09-23 | 2007-04-06 | 주식회사 한독약품 | 경구투여를 위한 당뇨병 치료용 약제학적 복합제제 |
US20090162516A1 (en) * | 2007-12-21 | 2009-06-25 | Brown Solomon E | Edible, water-soluble film |
-
2014
- 2014-10-13 CA CA2927334A patent/CA2927334C/fr active Active
- 2014-10-13 EA EA201690751A patent/EA038558B1/ru unknown
- 2014-10-13 MY MYPI2016701359A patent/MY184297A/en unknown
- 2014-10-13 UA UAA201605185A patent/UA123893C2/uk unknown
- 2014-10-13 IN IN3221MU2013 patent/IN2013MU03221A/en unknown
- 2014-10-13 WO PCT/IN2014/000652 patent/WO2015083181A2/fr active Application Filing
- 2014-10-13 BR BR112016008356-3A patent/BR112016008356B1/pt active IP Right Grant
-
2016
- 2016-04-14 CL CL2016000880A patent/CL2016000880A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
UA123893C2 (uk) | 2021-06-23 |
MY184297A (en) | 2021-03-31 |
EA038558B1 (ru) | 2021-09-14 |
EA201690751A1 (ru) | 2016-08-31 |
CA2927334A1 (fr) | 2015-06-11 |
IN2013MU03221A (fr) | 2015-07-03 |
BR112016008356B1 (pt) | 2022-12-13 |
CL2016000880A1 (es) | 2017-01-27 |
BR112016008356A2 (pt) | 2017-08-01 |
WO2015083181A3 (fr) | 2015-12-03 |
WO2015083181A2 (fr) | 2015-06-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |
Effective date: 20191011 |
|
EEER | Examination request |
Effective date: 20191011 |
|
EEER | Examination request |
Effective date: 20191011 |
|
EEER | Examination request |
Effective date: 20191011 |
|
EEER | Examination request |
Effective date: 20191011 |
|
EEER | Examination request |
Effective date: 20191011 |