CA2927148A1 - Methods and compositions for treating cancer - Google Patents
Methods and compositions for treating cancer Download PDFInfo
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- CA2927148A1 CA2927148A1 CA2927148A CA2927148A CA2927148A1 CA 2927148 A1 CA2927148 A1 CA 2927148A1 CA 2927148 A CA2927148 A CA 2927148A CA 2927148 A CA2927148 A CA 2927148A CA 2927148 A1 CA2927148 A1 CA 2927148A1
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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Landscapes
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- Indole Compounds (AREA)
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| US201361895308P | 2013-10-24 | 2013-10-24 | |
| US61/895,308 | 2013-10-24 | ||
| PCT/US2014/061418 WO2015061229A1 (en) | 2013-10-24 | 2014-10-20 | Methods and compositions for treating cancer |
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| CA2927148A1 true CA2927148A1 (en) | 2015-04-30 |
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| US8232310B2 (en) * | 2006-12-29 | 2012-07-31 | Georgetown University | Targeting of EWS-FLI1 as anti-tumor therapy |
| ES2464461T3 (es) | 2008-09-22 | 2014-06-02 | Array Biopharma, Inc. | Compuestos de imidazo[1,2B]piridazina sustituidos como inhibidores de la TRK cinasa |
| MX2011004204A (es) | 2008-10-22 | 2011-08-12 | Array Biopharma Inc | Compuestos pirazolo [1,5-a] pirimidina sustituida como inhibidores de cinasa trk. |
| AR077468A1 (es) | 2009-07-09 | 2011-08-31 | Array Biopharma Inc | Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa |
| CN102971322B (zh) | 2010-05-20 | 2016-02-17 | 阵列生物制药公司 | 作为trk激酶抑制剂的大环化合物 |
| AU2013245812B2 (en) | 2012-04-12 | 2017-04-06 | Georgetown University | Methods and compositions for treating Ewing's sarcoma family of tumors |
| KR20160065986A (ko) * | 2013-10-24 | 2016-06-09 | 조지타운 유니버시티 | 암 치료용 방법 및 조성물 |
| AU2015328121B2 (en) | 2014-10-09 | 2019-11-21 | Oncternal Therapeutics, Inc. | Indolinone compounds and uses thereof |
| CA2967951C (en) | 2014-11-16 | 2023-11-07 | Array Biopharma, Inc. | Crystalline form of (s)-n-(5-((r)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate |
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| WO2015061229A1 (en) | 2015-04-30 |
| RU2016114498A3 (enExample) | 2018-08-13 |
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| US20170157089A1 (en) | 2017-06-08 |
| AU2014340398A1 (en) | 2016-06-09 |
| CN105848654A (zh) | 2016-08-10 |
| CN105848654B (zh) | 2018-10-02 |
| IL245281A0 (en) | 2016-06-30 |
| JP2016534084A (ja) | 2016-11-04 |
| EP3060207A4 (en) | 2017-04-12 |
| US20160263086A1 (en) | 2016-09-15 |
| KR20160065986A (ko) | 2016-06-09 |
| MX2016004678A (es) | 2017-03-10 |
| RU2016114498A (ru) | 2017-11-29 |
| EP3060207A1 (en) | 2016-08-31 |
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