CA2926853C - Methods and compositions comprising a combination of a vegf antagonist and an anti-ctla-4 antibody - Google Patents
Methods and compositions comprising a combination of a vegf antagonist and an anti-ctla-4 antibody Download PDFInfo
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- CA2926853C CA2926853C CA2926853A CA2926853A CA2926853C CA 2926853 C CA2926853 C CA 2926853C CA 2926853 A CA2926853 A CA 2926853A CA 2926853 A CA2926853 A CA 2926853A CA 2926853 C CA2926853 C CA 2926853C
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- antibody
- ctla
- tumor
- vegf
- vegf antagonist
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Landscapes
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| CA2942776C (en) | 2014-03-17 | 2023-01-24 | Adverum Biotechnologies, Inc. | Polyneucleotide cassette and expression vector for expression of a gene in cone cells using truncated m-opsin promoter |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| KR20170137730A (ko) | 2015-03-02 | 2017-12-13 | 애드베룸 바이오테크놀로지스, 인코포레이티드 | 망막 추상체에 폴리뉴클레오타이드의 유리체 내 전달을 위한 조성물 및 방법 |
| SI3303394T1 (sl) | 2015-05-29 | 2020-10-30 | Agenus Inc. | Protitelesa proti-CTLA-4 in postopki njihove uporabe |
| MA44054A (fr) * | 2015-12-18 | 2018-10-24 | Biogen Ma Inc | Plateforme d'anticorps bispécifique |
| KR20250057128A (ko) | 2015-12-30 | 2025-04-28 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| WO2017165778A1 (en) | 2016-03-24 | 2017-09-28 | Millennium Pharmaceuticals, Inc. | Methods of treating gastrointestinal immune-related adverse events in immune oncology treatments |
| US11542332B2 (en) | 2016-03-26 | 2023-01-03 | Bioatla, Inc. | Anti-CTLA4 antibodies, antibody fragments, their immunoconjugates and uses thereof |
| PT3795181T (pt) | 2016-06-16 | 2025-11-05 | Adverum Biotechnologies Inc | Tratamento de dmi com utilização da variante aav2 com aflibercept |
| CA3030298A1 (en) | 2016-07-20 | 2018-01-25 | Aerpio Therapeutics, Inc. | Humanized monoclonal antibodies that target ve-ptp (hptp-.beta.) |
| IL266918B2 (en) | 2016-12-07 | 2024-03-01 | Agenus Inc | Anti-ctla-4 antibodies and methods of use thereof |
| US11168327B2 (en) | 2017-01-31 | 2021-11-09 | Research Development Foundation | STEAP2 inhibitors for the treatment of liver cancers |
| MA50908A (fr) | 2017-11-17 | 2020-09-23 | Amgen Inc | Formulations de protéines de fusion vegfr-fc |
| SG11202007018QA (en) * | 2018-02-02 | 2020-08-28 | Oncoimmune Inc | Methods of selecting and designing safer and more effective anti-ctla-4 antibodies for cancer therapy |
| US12129299B2 (en) * | 2018-02-02 | 2024-10-29 | OncoC4, Inc. | Mutant anti-CTLA-4 antibodies with improved immunotherapeutic effect but attenuated adverse effects |
| MX2020009152A (es) | 2018-03-02 | 2020-11-09 | Kodiak Sciences Inc | Anticuerpos de il-6 y constructos de fusion y conjugados de los mismos. |
| WO2019222082A1 (en) | 2018-05-14 | 2019-11-21 | Oncoimmune, Inc. | Anti-cd24 compositions and uses thereof |
| CN120058958A (zh) | 2018-09-24 | 2025-05-30 | 视点制药公司 | 靶向HPTP-β（VE-PTP）和VEGF的多特异性抗体 |
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| CN111378044B (zh) * | 2018-12-28 | 2022-07-15 | 长春金赛药业有限责任公司 | 抗体融合蛋白、制备方法及其应用 |
| AU2020216368B2 (en) * | 2019-01-30 | 2025-04-24 | Amgen Inc. | Aflibercept attributes and methods of characterizing and modifying thereof |
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| DE19802753A1 (de) * | 1998-01-26 | 1999-07-29 | Merck Patent Gmbh | Coreaktive Trägermaterialien zur Heterogenisierung von Katalysatoren, Cokatalysatoren und Liganden |
| EE05627B1 (et) | 1998-12-23 | 2013-02-15 | Pfizer Inc. | CTLA-4 vastased inimese monoklonaalsed antikehad |
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2014
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- 2014-10-17 CA CA2926853A patent/CA2926853C/en active Active
- 2014-10-17 KR KR1020167013164A patent/KR102338453B1/ko active Active
- 2014-10-17 EA EA201690633A patent/EA037890B1/ru unknown
- 2014-10-17 MX MX2016004736A patent/MX377714B/es active IP Right Grant
- 2014-10-17 CN CN201480054902.1A patent/CN105636986B/zh active Active
- 2014-10-17 AU AU2014337135A patent/AU2014337135B2/en active Active
- 2014-10-17 WO PCT/US2014/061071 patent/WO2015058048A1/en not_active Ceased
- 2014-10-17 JP JP2016524116A patent/JP6607850B2/ja active Active
- 2014-10-17 US US15/026,460 patent/US9968674B2/en active Active
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|---|---|
| IL244599B (en) | 2019-10-31 |
| CN105636986A (zh) | 2016-06-01 |
| US20180236070A1 (en) | 2018-08-23 |
| KR102338453B1 (ko) | 2021-12-13 |
| WO2015058048A1 (en) | 2015-04-23 |
| US9968674B2 (en) | 2018-05-15 |
| EP3057990B1 (en) | 2019-09-04 |
| EA201690633A1 (ru) | 2016-08-31 |
| CN105636986B (zh) | 2020-05-12 |
| EP3057990A1 (en) | 2016-08-24 |
| US10532096B2 (en) | 2020-01-14 |
| MX2016004736A (es) | 2016-07-26 |
| JP2016539096A (ja) | 2016-12-15 |
| CA2926853A1 (en) | 2015-04-23 |
| AU2014337135B2 (en) | 2019-09-19 |
| MX377714B (es) | 2025-03-11 |
| EA037890B1 (ru) | 2021-06-01 |
| IL244599A0 (en) | 2016-04-21 |
| US20160243225A1 (en) | 2016-08-25 |
| KR20160067978A (ko) | 2016-06-14 |
| JP6607850B2 (ja) | 2019-11-20 |
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