CA2920173C - Antibody binding sites specific for egfrviii - Google Patents
Antibody binding sites specific for egfrviii Download PDFInfo
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- CA2920173C CA2920173C CA2920173A CA2920173A CA2920173C CA 2920173 C CA2920173 C CA 2920173C CA 2920173 A CA2920173 A CA 2920173A CA 2920173 A CA2920173 A CA 2920173A CA 2920173 C CA2920173 C CA 2920173C
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| PCT/EP2014/002177 WO2015018527A1 (en) | 2013-08-07 | 2014-08-07 | ANTIBODY BINDING SITES SPECIFIC FOR EGFRvIII |
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| US9212225B1 (en) * | 2014-07-01 | 2015-12-15 | Amphivena Therapeutics, Inc. | Bispecific CD33 and CD3 binding proteins |
| EP2982693A1 (en) | 2014-08-07 | 2016-02-10 | Affimed Therapeutics AG | CD3 binding domain |
| JP6616833B2 (ja) * | 2014-11-25 | 2019-12-04 | ファームアブシン インコーポレイテッド | 新規ＥＧＦＲｖＩＩＩ抗体及びこれを含む組成物 |
| JP2018516248A (ja) | 2015-05-29 | 2018-06-21 | アンフィヴェナ セラピューティクス，インク． | 二重特異性のｃｄ３３およびｃｄ３結合タンパク質を使用する方法 |
| EP3307319A4 (en) * | 2015-06-09 | 2019-05-22 | Memorial Sloan Kettering Cancer Center | T CELL RECEPTOR-SIMILAR ANTIBODIES SPECIFIC TO PEPTID OF THE LATENT EBV MEMBRANE PROTEIN 2A PRESENTED BY HUMAN HLA |
| WO2016204966A1 (en) | 2015-06-16 | 2016-12-22 | Genentech, Inc. | Anti-cd3 antibodies and methods of use |
| TWI796283B (zh) | 2015-07-31 | 2023-03-21 | 德商安美基研究（慕尼黑）公司 | Ｍｓｌｎ及ｃｄ３抗體構築體 |
| TWI744242B (zh) * | 2015-07-31 | 2021-11-01 | 德商安美基研究（慕尼黑）公司 | Egfrviii及cd3抗體構築體 |
| EA039859B1 (ru) | 2015-07-31 | 2022-03-21 | Эмджен Рисерч (Мюник) Гмбх | Биспецифические конструкты антител, связывающие egfrviii и cd3 |
| TWI829617B (zh) | 2015-07-31 | 2024-01-21 | 德商安美基研究（慕尼黑）公司 | Ｆｌｔ３及ｃｄ３抗體構築體 |
| US10221242B2 (en) | 2016-01-21 | 2019-03-05 | Pfizer Inc. | Antibodies specific for epidermal growth factor receptor variant III and their uses |
| ES2942362T3 (es) | 2016-01-21 | 2023-05-31 | Pfizer | Receptores quiméricos para el antígeno que se dirigen a la variante III del receptor del factor de crecimiento epidérmico |
| IL260920B (en) | 2016-02-03 | 2022-09-01 | Amgen Res Munich Gmbh | Constructs of psma and cd3 bispecific antigens that bind to t-cells, preparations containing them and uses thereof |
| CN107556386A (zh) * | 2016-06-30 | 2018-01-09 | 中国科学院深圳先进技术研究院 | 抗EGFRvIII和CD3特异性双靶向抗体、含双靶向抗体表达盒的微环DNA及应用 |
| RU2725950C1 (ru) * | 2016-08-05 | 2020-07-07 | И-Байолоджикс Инк. | Антитела против белка-1 запрограммированной клеточной смерти (pd-1) и их применение |
| CA3032806C (en) * | 2016-08-05 | 2021-04-27 | Y-Biologics Inc. | Antibody to programmed death-ligand 1 (pd-l1) and use thereof |
| CN106501518A (zh) * | 2017-01-06 | 2017-03-15 | 北京弘润天源生物技术股份有限公司 | 一种检测EGFRvⅢ的免疫组化抗体试剂及检测方法 |
| AU2018228719B2 (en) * | 2017-02-28 | 2023-03-30 | Affimed Gmbh | Tandem diabody for CD16A-directed NK-cell engagement |
| CA3089287A1 (en) | 2018-02-08 | 2019-08-15 | Genentech, Inc. | Bispecific antigen-binding molecules and methods of use |
| JP7288913B2 (ja) * | 2018-03-14 | 2023-06-08 | アフィメッド ゲゼルシャフト ミット ベシュレンクテル ハフツンク | 二重特異性ｅｇｆｒ／ｃｄ１６抗原結合タンパク質 |
| MX2021007307A (es) * | 2018-12-21 | 2021-07-07 | Hoffmann La Roche | Anticuerpos que se unen a cd3. |
| KR20210116478A (ko) * | 2019-01-14 | 2021-09-27 | 난징 레전드 바이오테크 씨오., 엘티디. | 키메라 수용체 폴리펩티드 및 이의 용도 |
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| EP4154910A4 (en) * | 2020-06-30 | 2024-09-11 | Harbour Biomed (Shanghai) Co., Ltd | Binding protein having h2l2 and hcab structures |
| WO2022159685A2 (en) * | 2021-01-22 | 2022-07-28 | Vanderbilt University | Sars-cov-2 coronavirus antibodies and uses thereof |
| AU2022273541A1 (en) | 2021-05-14 | 2023-11-30 | Genentech, Inc. | Methods for treatment of cd20-positive proliferative disorder with mosunetuzumab and polatuzumab vedotin |
| WO2023287941A2 (en) * | 2021-07-16 | 2023-01-19 | Medical Guidance Systems, Llc | Anti-tax interacting protein-1 (tip1) binding molecules |
| WO2023125729A1 (zh) * | 2021-12-31 | 2023-07-06 | 康源博创生物科技(北京)有限公司 | 一种抗cd3的人源化抗体及其在制备双特异性抗体中的应用 |
| WO2024258870A2 (en) | 2023-06-12 | 2024-12-19 | Amgen Inc. | Lymphotoxin beta receptor agonist binding proteins |
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| US20100056762A1 (en) * | 2001-05-11 | 2010-03-04 | Old Lloyd J | Specific binding proteins and uses thereof |
| CN104059147A (zh) * | 2003-06-27 | 2014-09-24 | 艾默根佛蒙特有限公司 | 针对表皮生长因子受体的缺失突变体的抗体及其使用 |
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2014
- 2014-08-07 SI SI201431808T patent/SI3030581T1/sl unknown
- 2014-08-07 EP EP14758087.2A patent/EP3030581B1/en active Active
- 2014-08-07 CN CN201480045405.5A patent/CN105555804B/zh active Active
- 2014-08-07 AU AU2014304930A patent/AU2014304930B2/en active Active
- 2014-08-07 DK DK14758087.2T patent/DK3030581T3/da active
- 2014-08-07 WO PCT/EP2014/002177 patent/WO2015018527A1/en not_active Ceased
- 2014-08-07 RU RU2016106577A patent/RU2696892C2/ru active
- 2014-08-07 HU HUE14758087A patent/HUE054057T2/hu unknown
- 2014-08-07 JP JP2016532264A patent/JP6529498B2/ja active Active
- 2014-08-07 LT LTEP14758087.2T patent/LT3030581T/lt unknown
- 2014-08-07 HR HRP20210561TT patent/HRP20210561T1/hr unknown
- 2014-08-07 CA CA2920173A patent/CA2920173C/en active Active
-
2016
- 2016-02-04 US US15/015,261 patent/US10273309B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016536322A (ja) | 2016-11-24 |
| AU2014304930A1 (en) | 2016-02-25 |
| CN105555804A (zh) | 2016-05-04 |
| EP3030581A1 (en) | 2016-06-15 |
| CN105555804B (zh) | 2020-12-25 |
| DK3030581T3 (da) | 2021-04-12 |
| HUE054057T2 (hu) | 2021-08-30 |
| BR112016002610A8 (pt) | 2018-01-23 |
| US10273309B2 (en) | 2019-04-30 |
| SI3030581T1 (sl) | 2021-07-30 |
| US20160152728A1 (en) | 2016-06-02 |
| WO2015018527A1 (en) | 2015-02-12 |
| HK1218552A1 (zh) | 2017-02-24 |
| CA2920173A1 (en) | 2015-02-12 |
| BR112016002610A2 (pt) | 2017-09-12 |
| HRP20210561T1 (hr) | 2021-05-14 |
| RU2016106577A (ru) | 2017-09-14 |
| AU2014304930B2 (en) | 2019-11-21 |
| RU2696892C2 (ru) | 2019-08-07 |
| JP6529498B2 (ja) | 2019-06-12 |
| EP3030581B1 (en) | 2021-01-20 |
| LT3030581T (lt) | 2021-05-25 |
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