CA2915405A1 - Compositions and methods for treating metabolic disorders - Google Patents
Compositions and methods for treating metabolic disorders Download PDFInfo
- Publication number
- CA2915405A1 CA2915405A1 CA2915405A CA2915405A CA2915405A1 CA 2915405 A1 CA2915405 A1 CA 2915405A1 CA 2915405 A CA2915405 A CA 2915405A CA 2915405 A CA2915405 A CA 2915405A CA 2915405 A1 CA2915405 A1 CA 2915405A1
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- Prior art keywords
- key element
- metabolic disorder
- receptor agonist
- sumn
- antagonist
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361834864P | 2013-06-13 | 2013-06-13 | |
| US61/834,864 | 2013-06-13 | ||
| PCT/US2014/042397 WO2014201411A1 (en) | 2013-06-13 | 2014-06-13 | Compositions and methods for treating metabolic disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2915405A1 true CA2915405A1 (en) | 2014-12-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2915405A Abandoned CA2915405A1 (en) | 2013-06-13 | 2014-06-13 | Compositions and methods for treating metabolic disorders |
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|---|---|
| US (3) | US20150011554A1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3311842A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2016521755A (cg-RX-API-DMAC7.html) |
| CN (1) | CN105579575A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2014277952A1 (cg-RX-API-DMAC7.html) |
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| CA (1) | CA2915405A1 (cg-RX-API-DMAC7.html) |
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| US9655865B2 (en) | 2002-07-29 | 2017-05-23 | Veroscience, Llc | Therapeutic treatment for metabolic syndrome, type 2 diabetes, obesity, or prediabetes |
| US8821915B2 (en) | 2002-08-09 | 2014-09-02 | Veroscience, Llc | Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders |
| US20090137598A1 (en) | 2007-06-21 | 2009-05-28 | Veroscience, Llc | Method of treating metabolic disorders and depression with dopamine receptor agonists |
| US20100035886A1 (en) | 2007-06-21 | 2010-02-11 | Veroscience, Llc | Parenteral formulations of dopamine agonists |
| US8741918B2 (en) | 2007-06-21 | 2014-06-03 | Veroscience Llc | Parenteral formulations of dopamine agonists |
| US9352025B2 (en) | 2009-06-05 | 2016-05-31 | Veroscience Llc | Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders |
| US8431155B1 (en) | 2012-04-30 | 2013-04-30 | Veroscience Llc | Bromocriptine formulations |
| AU2017254650A1 (en) | 2016-04-20 | 2018-11-15 | Veroscience Llc | Composition and method for treating metabolic disorders |
| EP3697418B1 (en) | 2017-10-18 | 2024-07-24 | VeroScience LLC | Improved bromocriptine formulations |
| WO2019113110A2 (en) * | 2017-12-05 | 2019-06-13 | Peter Vanderklish | Modulation of ampa/kainate receptors for the treatment of hypoglycemia |
| WO2020236696A1 (en) * | 2019-05-23 | 2020-11-26 | Dignity Health | Inhibitory interneuron treatment methods, uses and compositions for diabetes |
| US11607455B2 (en) | 2019-09-23 | 2023-03-21 | Veroscience Llc | Method for inducing tumor regression |
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2014
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| BR112015031249A2 (pt) | 2017-07-25 |
| MX2015017253A (es) | 2016-04-19 |
| US20220142960A1 (en) | 2022-05-12 |
| EP3008167A4 (en) | 2017-06-07 |
| WO2014201411A1 (en) | 2014-12-18 |
| CN105579575A (zh) | 2016-05-11 |
| US20150011554A1 (en) | 2015-01-08 |
| EP3311842A1 (en) | 2018-04-25 |
| AU2014277952A1 (en) | 2016-01-28 |
| JP2016521755A (ja) | 2016-07-25 |
| US20190160059A1 (en) | 2019-05-30 |
| EP3008167A1 (en) | 2016-04-20 |
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