CA2906624A1 - Anti-plasma kallikrein antibodies - Google Patents
Anti-plasma kallikrein antibodiesInfo
- Publication number
- CA2906624A1 CA2906624A1 CA2906624A CA2906624A CA2906624A1 CA 2906624 A1 CA2906624 A1 CA 2906624A1 CA 2906624 A CA2906624 A CA 2906624A CA 2906624 A CA2906624 A CA 2906624A CA 2906624 A1 CA2906624 A1 CA 2906624A1
- Authority
- CA
- Canada
- Prior art keywords
- antibody
- pkal
- isolated antibody
- antibodies
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Public Health (AREA)
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- Molecular Biology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Microbiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA3208188A CA3208188A1 (en) | 2013-03-15 | 2014-03-14 | Anti-plasma kallikrein antibodies |
Applications Claiming Priority (3)
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| US201361791822P | 2013-03-15 | 2013-03-15 | |
| US61/791,822 | 2013-03-15 | ||
| PCT/US2014/027100 WO2014152232A2 (en) | 2013-03-15 | 2014-03-14 | Anti-plasma kallikrein antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3208188A Division CA3208188A1 (en) | 2013-03-15 | 2014-03-14 | Anti-plasma kallikrein antibodies |
Publications (1)
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| CA2906624A1 true CA2906624A1 (en) | 2014-09-25 |
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| CA2906624A Pending CA2906624A1 (en) | 2013-03-15 | 2014-03-14 | Anti-plasma kallikrein antibodies |
| CA3208188A Pending CA3208188A1 (en) | 2013-03-15 | 2014-03-14 | Anti-plasma kallikrein antibodies |
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| CA3208188A Pending CA3208188A1 (en) | 2013-03-15 | 2014-03-14 | Anti-plasma kallikrein antibodies |
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| EP (2) | EP2970502A4 (enExample) |
| JP (2) | JP2016513682A (enExample) |
| KR (1) | KR20150132473A (enExample) |
| CN (3) | CN118406688A (enExample) |
| AU (4) | AU2014240045A1 (enExample) |
| CA (2) | CA2906624A1 (enExample) |
| HK (1) | HK1218762A1 (enExample) |
| IL (2) | IL292121B2 (enExample) |
| WO (1) | WO2014152232A2 (enExample) |
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| ES2905545T3 (es) | 2010-01-06 | 2022-04-11 | Takeda Pharmaceuticals Co | Proteínas de unión a calicreína plasmática |
| IL269565B2 (en) | 2011-01-06 | 2024-06-01 | Dyax Corp | Plasma kallikrein binding proteins |
| EP2970502A4 (en) | 2013-03-15 | 2016-11-30 | Dyax Corp | ANTI-PLASMA KALLIKREIN ANTIBODY |
| KR102424183B1 (ko) | 2014-01-21 | 2022-07-26 | 다케다 파머수티컬 컴패니 리미티드 | 혈장 칼리크레인 결합 단백질 및 유전성 혈관부종을 치료하는 데 있어서의 이의 용도 |
| EP3122782A4 (en) | 2014-03-27 | 2017-09-13 | Dyax Corp. | Compositions and methods for treatment of diabetic macular edema |
| EP3240570B1 (en) * | 2015-01-02 | 2025-09-24 | Takeda Pharmaceutical Company Limited | Bispecific antibodies against plasma kallikrein and factor xii |
| US20180298110A1 (en) * | 2015-03-30 | 2018-10-18 | Dyax Corp. | Plasma kallikrein inhibitors and uses thereof for preventing hereditary angioedema attack |
| EA201890340A1 (ru) | 2015-07-21 | 2018-09-28 | Дайэкс Корп. | Моноклональное антитело-ингибитор фактора xiia |
| CN116077648A (zh) * | 2015-12-11 | 2023-05-09 | 武田药品工业株式会社 | 血浆激肽释放酶抑制剂及其治疗遗传性血管性水肿发作的用途 |
| AU2018350992A1 (en) * | 2017-10-18 | 2020-05-21 | Regenxbio Inc. | Fully-human post-translationally modified antibody therapeutics |
| CA3110689A1 (en) * | 2018-08-30 | 2020-03-05 | Dyax Corp. | Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack |
| JP2022536692A (ja) | 2019-06-11 | 2022-08-18 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | 調節不全の血漿カリクレインによって媒介される疾患の治療のための抗体のアデノ随伴ウイルスベクター送達 |
| CN116829595A (zh) | 2020-12-16 | 2023-09-29 | 武田药品工业株式会社 | 用于治疗由失调的血浆激肽释放酶介导的疾病的抗体的腺相关病毒载体递送 |
| CN114790246A (zh) * | 2021-01-25 | 2022-07-26 | 成都康弘生物科技有限公司 | 一种抗体及其用途 |
| CN114790245A (zh) * | 2021-01-25 | 2022-07-26 | 成都康弘生物科技有限公司 | 一种抗体及其用途 |
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| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US5444156A (en) | 1985-07-12 | 1995-08-22 | Temple University-Of The Commonwealth System Of Higher Education | Monoclonal antibodies to human plasma prekallikrein |
| US4777127A (en) | 1985-09-30 | 1988-10-11 | Labsystems Oy | Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| EP0296171A4 (en) | 1986-03-03 | 1989-11-07 | Brigham & Womens Hospital | ASSESSMENT PROCEDURE FOR NEPHROTOXICITY. |
| US4704692A (en) | 1986-09-02 | 1987-11-03 | Ladner Robert C | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
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| AP129A (en) | 1988-06-03 | 1991-04-17 | Smithkline Biologicals S A | Expression of retrovirus gag protein eukaryotic cells |
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| EP0454781B1 (en) | 1989-01-23 | 1998-12-16 | Chiron Corporation | Recombinant cells for therapies of infection and hyperproliferative disorders and preparation thereof |
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| EP3594244A1 (en) | 2020-01-15 |
| AU2021200144B2 (en) | 2024-06-20 |
| CN118406688A (zh) | 2024-07-30 |
| US20230002509A1 (en) | 2023-01-05 |
| AU2019200638B2 (en) | 2021-01-28 |
| CA3208188A1 (en) | 2014-09-25 |
| HK1218762A1 (zh) | 2017-03-10 |
| KR20150132473A (ko) | 2015-11-25 |
| IL241334B (en) | 2022-05-01 |
| JP2016513682A (ja) | 2016-05-16 |
| EP2970502A4 (en) | 2016-11-30 |
| IL292121B1 (en) | 2023-10-01 |
| IL292121A (en) | 2022-06-01 |
| BR112015022282A2 (pt) | 2017-10-10 |
| JP2020007354A (ja) | 2020-01-16 |
| EP2970502A2 (en) | 2016-01-20 |
| WO2014152232A3 (en) | 2014-11-13 |
| CN111704672A (zh) | 2020-09-25 |
| US12110343B2 (en) | 2024-10-08 |
| US11299553B2 (en) | 2022-04-12 |
| CN105051068A (zh) | 2015-11-11 |
| US20190185580A1 (en) | 2019-06-20 |
| AU2021200144A1 (en) | 2021-03-18 |
| IL241334A0 (en) | 2015-11-30 |
| AU2014240045A1 (en) | 2015-09-10 |
| CN111704672B (zh) | 2024-06-04 |
| US20160017055A1 (en) | 2016-01-21 |
| AU2019200638A1 (en) | 2019-02-21 |
| US20250129182A1 (en) | 2025-04-24 |
| AU2024219756A1 (en) | 2024-10-10 |
| IL292121B2 (en) | 2024-02-01 |
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