CA2905571A1 - Heat-stable respiratory syncytial virus prefusion f protein oligomers and their use in immunological compositions - Google Patents
Heat-stable respiratory syncytial virus prefusion f protein oligomers and their use in immunological compositions Download PDFInfo
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- CA2905571A1 CA2905571A1 CA2905571A CA2905571A CA2905571A1 CA 2905571 A1 CA2905571 A1 CA 2905571A1 CA 2905571 A CA2905571 A CA 2905571A CA 2905571 A CA2905571 A CA 2905571A CA 2905571 A1 CA2905571 A1 CA 2905571A1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/828,667 US9060975B2 (en) | 2013-03-14 | 2013-03-14 | Heat-stable respiratory syncytial virus F protein oligomers and their use in immunological compositions |
| US13/828,667 | 2013-03-14 | ||
| PCT/EP2014/054804 WO2014140083A1 (en) | 2013-03-14 | 2014-03-12 | Heat-stable respiratory syncytial virus prefusion f protein oligomers and their use in immunological compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2905571A1 true CA2905571A1 (en) | 2014-09-18 |
Family
ID=50241453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2905571A Abandoned CA2905571A1 (en) | 2013-03-14 | 2014-03-12 | Heat-stable respiratory syncytial virus prefusion f protein oligomers and their use in immunological compositions |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9060975B2 (enExample) |
| EP (2) | EP3178840A1 (enExample) |
| JP (1) | JP6285469B2 (enExample) |
| CN (2) | CN107029227A (enExample) |
| AU (1) | AU2014230822B2 (enExample) |
| BR (1) | BR112015022617A2 (enExample) |
| CA (1) | CA2905571A1 (enExample) |
| WO (1) | WO2014140083A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108602858A (zh) * | 2015-10-29 | 2018-09-28 | 埃默里大学 | 嵌合rsv、免疫原性组合物以及使用方法 |
| US11471524B2 (en) | 2013-03-14 | 2022-10-18 | Emory University | Recombinant RSV with silent mutations, vaccines, and methods related thereto |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS60056B1 (sr) | 2013-02-01 | 2020-04-30 | Medimmune Llc | Epitopi f proteina respiratornog sincicijalnog virusa |
| MX2018012094A (es) * | 2016-04-05 | 2019-01-10 | Janssen Vaccines & Prevention Bv | Proteinas f de prefusion del virus respiratorio sincicial (vrs) solubles y estabilizadas. |
| SG11201810078PA (en) * | 2016-05-30 | 2018-12-28 | Janssen Vaccines & Prevention Bv | Stabilized pre-fusion rsv f proteins |
| CN108300705B (zh) * | 2017-01-12 | 2021-10-22 | 厦门大学 | 稳定呼吸道合胞病毒融合蛋白的方法 |
| CN110506060B (zh) | 2017-03-30 | 2024-05-07 | 昆士兰大学 | 嵌合分子及其用途 |
| EP3606942B1 (en) | 2017-04-04 | 2025-06-11 | University of Washington | Self-assembling protein nanostructures displaying paramyxovirus and/or pneumovirus f proteins and their use |
| WO2019063844A1 (en) * | 2017-09-29 | 2019-04-04 | Universiteit Antwerpen | VACCINATION AGAINST SYNCYTIAL RESPIRATORY VIRUS |
| WO2019147749A2 (en) * | 2018-01-29 | 2019-08-01 | Merck Sharp & Dohme Corp. | Stabilized rsv f proteins and uses thereof |
| CN110684747B (zh) | 2018-07-06 | 2024-05-24 | 厦门大学 | 灭活及保存呼吸道合胞病毒的方法 |
| US20200129446A1 (en) | 2018-10-29 | 2020-04-30 | University Of Iowa Research Foundation | Respiratory syncytial virus (rsv) polyanhydride nanoparticle vaccine |
| KR102725189B1 (ko) * | 2018-11-01 | 2024-10-31 | 에스케이바이오사이언스(주) | 재조합 호흡기 세포융합 바이러스 f 단백질 및 이를 포함하는 백신 조성물 |
| CN109694400A (zh) * | 2019-01-31 | 2019-04-30 | 苏州高泓利康生物科技有限公司 | 一种表达呼吸道合胞病毒f蛋白及其制备方法 |
| JP7657727B2 (ja) | 2019-04-02 | 2025-04-07 | サノフイ | 抗原性多量体呼吸器合胞体ウイルスポリペプチド |
| CN110054668B (zh) * | 2019-04-25 | 2021-09-10 | 北京交通大学 | 一种呼吸道合胞病毒融合前f蛋白及其应用 |
| JP7818504B2 (ja) | 2019-09-04 | 2026-02-20 | ユニヴァーシティ オブ ワシントン | パラミクソウイルスおよび／またはニューモウイルスのｆタンパク質を提示する自己組織化タンパク質ナノ構造体ならびにその使用 |
| CN111303245B (zh) * | 2020-02-21 | 2023-06-27 | 成都奥达生物科技有限公司 | 一种抗合胞病毒膜融合抑制剂 |
| US20230173055A1 (en) * | 2020-04-22 | 2023-06-08 | POSTECH Research and Business Development Foundation | Influenza virus surface protein-derived recombinant hemagglutinin protein forming trimer, and use thereof |
| US20230174591A1 (en) * | 2020-05-19 | 2023-06-08 | National Research Council Of Canada | Use of Human Resistin as a Trimerization Partner for Expression of Trimeric Proteins |
| CN112480217B (zh) * | 2020-11-30 | 2022-04-08 | 广州阿格纳生物医药制造有限公司 | 基于SARS-CoV-2的S抗原蛋白的疫苗和组合物 |
| IL322502A (en) * | 2023-02-03 | 2025-09-01 | Novavax Inc | RSV F vaccine formulations |
| WO2024192698A1 (zh) * | 2023-03-22 | 2024-09-26 | 中科牧维(南京)生物科技有限公司 | 靶向人呼吸道合胞病毒融合糖蛋白的多肽拮抗剂 |
| AU2024287014A1 (en) * | 2023-06-07 | 2026-01-22 | Sichuan Clover Biopharmaceuticals, Inc. | Rsv vaccine composition, method and use thereof |
| CN117886902B (zh) * | 2023-12-21 | 2024-11-26 | 易康生物(苏州)有限公司 | 改良的呼吸道合胞病毒融合f蛋白突变体及其应用 |
| CN121221753A (zh) * | 2025-02-14 | 2025-12-30 | 北京悦康科创医药科技股份有限公司 | 一种膜融合抑制多肽在抗肺病毒科病毒感染中的应用 |
| CN120329390A (zh) * | 2025-03-03 | 2025-07-18 | 中国医学科学院医学生物学研究所 | 基于异源三聚体基序的蛋白的改造及应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0916726A1 (en) | 1997-11-13 | 1999-05-19 | Rijksuniversiteit te Groningen | Attaching substances to micro-organisms |
| DE60232071D1 (de) | 2001-06-11 | 2009-06-04 | Applied Nanosystems Bv | Verfahren zur bindung von acma-typ protein anker fusionen an mikroorganismen zellwandmaterialien |
| EP1997830A1 (en) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV specific binding molecules and means for producing them |
| PL2445526T3 (pl) | 2009-06-24 | 2017-08-31 | Glaxosmithkline Biologicals S.A. | Rekombinowane antygeny rsv |
| SG176807A1 (en) * | 2009-06-24 | 2012-01-30 | Id Biomedical Corp Quebec | Vaccine |
| EP4183412B1 (en) * | 2009-07-15 | 2024-08-14 | GlaxoSmithKline Biologicals SA | Rsv f protein compositions and methods for making same |
| US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
| JP6069295B2 (ja) | 2011-03-22 | 2017-02-01 | ミュコシス ベー．フェー． | 免疫組成物、免疫組成物の製造方法、疾患の治療剤または予防剤、組み替えポリペプチド、核酸配列、ベクターおよび宿主細胞 |
| RS56748B1 (sr) | 2011-05-13 | 2018-03-30 | Glaxosmithkline Biologicals Sa | Pre-fuzioni rsv f antigeni |
-
2013
- 2013-03-14 US US13/828,667 patent/US9060975B2/en not_active Ceased
-
2014
- 2014-03-12 WO PCT/EP2014/054804 patent/WO2014140083A1/en not_active Ceased
- 2014-03-12 EP EP16200916.1A patent/EP3178840A1/en not_active Withdrawn
- 2014-03-12 BR BR112015022617A patent/BR112015022617A2/pt not_active IP Right Cessation
- 2014-03-12 CA CA2905571A patent/CA2905571A1/en not_active Abandoned
- 2014-03-12 JP JP2015562115A patent/JP6285469B2/ja not_active Expired - Fee Related
- 2014-03-12 CN CN201710040168.9A patent/CN107029227A/zh active Pending
- 2014-03-12 EP EP14709318.1A patent/EP2970393B1/en not_active Not-in-force
- 2014-03-12 AU AU2014230822A patent/AU2014230822B2/en not_active Ceased
- 2014-03-12 CN CN201480022815.8A patent/CN105246910A/zh active Pending
-
2016
- 2016-03-26 US US15/081,854 patent/USRE47471E1/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11471524B2 (en) | 2013-03-14 | 2022-10-18 | Emory University | Recombinant RSV with silent mutations, vaccines, and methods related thereto |
| US12186386B2 (en) | 2013-03-14 | 2025-01-07 | Emory University and Children's Healthcare of Atlanta, Inc. | Recombinant RSV with silent mutations, vaccines, and methods related thereto |
| CN108602858A (zh) * | 2015-10-29 | 2018-09-28 | 埃默里大学 | 嵌合rsv、免疫原性组合物以及使用方法 |
| US12257296B2 (en) | 2015-10-29 | 2025-03-25 | Emory University | Chimeric RSV, immunogenic compositions, and methods of use |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2014230822A1 (en) | 2015-10-01 |
| CN105246910A (zh) | 2016-01-13 |
| US20140271696A1 (en) | 2014-09-18 |
| BR112015022617A2 (pt) | 2017-10-31 |
| US9060975B2 (en) | 2015-06-23 |
| JP2016510983A (ja) | 2016-04-14 |
| CN107029227A (zh) | 2017-08-11 |
| WO2014140083A1 (en) | 2014-09-18 |
| EP2970393A1 (en) | 2016-01-20 |
| JP6285469B2 (ja) | 2018-02-28 |
| EP2970393B1 (en) | 2017-01-11 |
| USRE47471E1 (en) | 2019-07-02 |
| AU2014230822B2 (en) | 2018-04-12 |
| EP3178840A1 (en) | 2017-06-14 |
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Legal Events
| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20200312 |