CA2903121C - Methods, systems and computer program products for non-invasive determination of blood flow distribution using speckle imaging techniques and hemodynamic modeling - Google Patents

Methods, systems and computer program products for non-invasive determination of blood flow distribution using speckle imaging techniques and hemodynamic modeling Download PDF

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Publication number
CA2903121C
CA2903121C CA2903121A CA2903121A CA2903121C CA 2903121 C CA2903121 C CA 2903121C CA 2903121 A CA2903121 A CA 2903121A CA 2903121 A CA2903121 A CA 2903121A CA 2903121 C CA2903121 C CA 2903121C
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region
interest
flow
image
blood flow
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French (fr)
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CA2903121A1 (en
Inventor
Thomas Bruce Ferguson, Jr.
Xin-hua HU
Cheng Chen
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East Carolina University
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East Carolina University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A61B5/0261—Measuring blood flow using optical means, e.g. infrared light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
    • A61B5/004—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0044—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/33—Heart-related electrical modalities, e.g. electrocardiography [ECG] specially adapted for cooperation with other devices
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/48—Laser speckle optics
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077—Devices for viewing the surface of the body, e.g. camera, magnifying lens

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physiology (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Optics & Photonics (AREA)
  • Vascular Medicine (AREA)
  • Quality & Reliability (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CA2903121A 2013-03-15 2014-03-14 Methods, systems and computer program products for non-invasive determination of blood flow distribution using speckle imaging techniques and hemodynamic modeling Active CA2903121C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/833,862 2013-03-15
US13/833,862 US9226673B2 (en) 2011-01-10 2013-03-15 Methods, systems and computer program products for non-invasive determination of blood flow distribution using speckle imaging techniques and hemodynamic modeling
PCT/US2014/027696 WO2014152753A1 (en) 2013-03-15 2014-03-14 Methods, systems and computer program products for non-invasive determination of blood flow distribution using speckle imaging techniques and hemodynamic modeling

Publications (2)

Publication Number Publication Date
CA2903121A1 CA2903121A1 (en) 2014-09-25
CA2903121C true CA2903121C (en) 2022-01-11

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CA2903121A Active CA2903121C (en) 2013-03-15 2014-03-14 Methods, systems and computer program products for non-invasive determination of blood flow distribution using speckle imaging techniques and hemodynamic modeling

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US (1) US9226673B2 (enExample)
EP (1) EP2967380B1 (enExample)
JP (1) JP6706199B2 (enExample)
CN (1) CN105358052A (enExample)
CA (1) CA2903121C (enExample)
WO (1) WO2014152753A1 (enExample)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070122344A1 (en) 2005-09-02 2007-05-31 University Of Rochester Medical Center Office Of Technology Transfer Intraoperative determination of nerve location
US20080161744A1 (en) 2006-09-07 2008-07-03 University Of Rochester Medical Center Pre-And Intra-Operative Localization of Penile Sentinel Nodes
US8406860B2 (en) 2008-01-25 2013-03-26 Novadaq Technologies Inc. Method for evaluating blush in myocardial tissue
US10219742B2 (en) 2008-04-14 2019-03-05 Novadaq Technologies ULC Locating and analyzing perforator flaps for plastic and reconstructive surgery
EP2687235A3 (en) 2008-05-02 2014-11-05 Novadaq Technologies Inc. Methods for production and use of substance-loaded erythrocytes (S-LES) for observation and treatment of microvascular hemodynamics
US9066686B2 (en) 2008-07-10 2015-06-30 Novadaq Technologies Inc. Functional optical coherent imaging
US10492671B2 (en) 2009-05-08 2019-12-03 Novadaq Technologies ULC Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest
WO2012107050A1 (en) * 2011-02-08 2012-08-16 Region Nordjylland, Aalborg Sygehus A system for determining flow properties of a blood vessel
WO2013160861A1 (en) 2012-04-27 2013-10-31 Aïmago S.A. Optical coherent imaging medical device
EP2863801B8 (en) 2012-06-21 2024-06-12 Stryker Corporation Quantification and analysis of angiography and perfusion
JP6076111B2 (ja) * 2013-02-07 2017-02-08 浜松ホトニクス株式会社 塊状細胞評価方法および塊状細胞評価装置
US10028668B2 (en) 2014-05-06 2018-07-24 Alivecor, Inc. Blood pressure monitor
CN106413536A (zh) * 2014-05-23 2017-02-15 柯惠有限合伙公司 用于在腹腔镜中为血流成像的系统
US10178959B1 (en) * 2014-07-10 2019-01-15 Verily Life Sciences Llc Non-invasive flow monitoring
JP6507509B2 (ja) * 2014-07-18 2019-05-08 ソニー株式会社 流路撮像装置及び流路撮像方法
KR102299361B1 (ko) 2014-09-03 2021-09-07 삼성전자주식회사 혈압을 모니터링하는 장치 및 방법, 혈압 모니터링 기능을 갖는 웨어러블 디바이스
AU2015327665B2 (en) 2014-09-29 2018-09-27 Stryker European Operations Limited Imaging a target fluorophore in a biological material in the presence of autofluorescence
AU2014408488B2 (en) 2014-10-09 2019-07-18 Stryker European Operations Limited Quantification of absolute blood flow in tissue using fluorescence-mediated photoplethysmography
US11553844B2 (en) 2014-10-14 2023-01-17 East Carolina University Methods, systems and computer program products for calculating MetaKG signals for regions having multiple sets of optical characteristics
CN107405094A (zh) 2014-10-14 2017-11-28 东卡罗莱娜大学 用于使用成像技术来可视化解剖结构以及血流和灌注生理机能的方法、系统和计算机程序产品
CN107257655B (zh) * 2014-10-14 2020-06-16 东卡罗莱娜大学 用于利用从多谱段血液流动和灌注成像获取的信号确定血液动力学状态参数的方法、系统和计算机程序产品
US10194808B1 (en) * 2014-12-29 2019-02-05 Verily Life Sciences Llc Correlated hemodynamic measurements
KR102411658B1 (ko) 2015-01-15 2022-06-21 삼성전자주식회사 생체 정보 검출 장치
US10070796B2 (en) * 2015-02-04 2018-09-11 General Electric Company Systems and methods for quantitative microcirculation state monitoring
JP2016151524A (ja) * 2015-02-18 2016-08-22 ソニー株式会社 スペックルイメージング装置、スペックルイメージングシステム及びスペックルイメージング方法
KR102384225B1 (ko) 2015-03-06 2022-04-07 삼성전자주식회사 혈압 측정 장치 및 방법
US10058256B2 (en) 2015-03-20 2018-08-28 East Carolina University Multi-spectral laser imaging (MSLI) methods and systems for blood flow and perfusion imaging and quantification
US10390718B2 (en) 2015-03-20 2019-08-27 East Carolina University Multi-spectral physiologic visualization (MSPV) using laser imaging methods and systems for blood flow and perfusion imaging and quantification in an endoscopic design
EP3291725B1 (en) * 2015-05-07 2024-07-24 Stryker Corporation Methods and systems for laser speckle imaging of tissue using a color image sensor
DE102015216115B4 (de) 2015-08-24 2023-08-10 Siemens Healthcare Gmbh Verfahren und System zum Bestimmen eines Triggersignals
KR102434701B1 (ko) 2015-09-01 2022-08-22 삼성전자주식회사 생체 정보 획득 장치 및 생체 정보 획득 방법과 생체 정보 검사 장치
EP3364858B1 (en) 2015-10-22 2023-12-13 Tyto Care Ltd. System, method and computer program product for physiological monitoring
WO2017091492A1 (en) 2015-11-23 2017-06-01 Heartflow, Inc. Systems and methods for assessing organ and/or tissue transplantation by simulating one or more transplant characteristics
JP2017170064A (ja) * 2016-03-25 2017-09-28 ソニー株式会社 画像解析装置、画像解析方法
CN109152544B (zh) * 2016-04-06 2021-09-10 雷瑟联合科技有限公司 使用粘附激光散斑对比分析的血流量测量系统
RU2648029C2 (ru) * 2016-08-10 2018-03-21 Самсунг Электроникс Ко., Лтд. Устройство и способ измерения кровяного давления
KR101815388B1 (ko) * 2016-08-11 2018-01-08 서울대학교산학협력단 유체 속도 측정 장치 및 방법
KR102655671B1 (ko) 2016-10-12 2024-04-05 삼성전자주식회사 생체정보 추정 장치 및 방법
WO2018145193A1 (en) 2017-02-10 2018-08-16 Novadaq Technologies ULC Open-field handheld fluorescence imaging systems and methods
CN108523872A (zh) * 2017-03-06 2018-09-14 上海健康医学院 一种理疗功效评估方法及系统
US10813597B2 (en) * 2017-04-14 2020-10-27 The Regents Of The University Of California Non-invasive hemodynamic assessment via interrogation of biological tissue using a coherent light source
KR101952013B1 (ko) * 2017-04-28 2019-04-29 포항공과대학교 산학협력단 정맥혈관 네비게이터 시스템 및 그 방법
US20210145295A1 (en) * 2017-05-16 2021-05-20 Sony Corporation Image processing apparatus and method and image processing system
CN107389139B (zh) * 2017-08-03 2023-01-24 尤立荣 微流量视觉测量装置及视觉测量方法
EP3801211A1 (en) 2018-06-08 2021-04-14 East Carolina University Determining peripheral oxygen saturation (spo2) and hemoglobin concentration using multi-spectral laser imaging (msli) methods and systems
JP2021529053A (ja) * 2018-06-28 2021-10-28 チルドレンズ ナショナル メディカル センターＣｈｉｌｄｒｅｎ’Ｓ Ｎａｔｉｏｎａｌ Ｍｅｄｉｃａｌ Ｃｅｎｔｅｒ 腹腔鏡検査における血流及び組織灌流を無染料で視覚化するための方法及びシステム
JP2021164494A (ja) * 2018-07-02 2021-10-14 ソニーグループ株式会社 医療用観察システム、医療用観察装置、及び医療用観察装置の駆動方法
CN109222952A (zh) * 2018-07-17 2019-01-18 上海健康医学院 一种激光散斑血流灌注成像方法
KR102545980B1 (ko) 2018-07-19 2023-06-21 액티브 서지컬, 인크. 자동화된 수술 로봇을 위한 비전 시스템에서 깊이의 다중 모달 감지를 위한 시스템 및 방법
CN109106360A (zh) * 2018-08-15 2019-01-01 河北科技大学 人体血液流速测量方法及其装置
US10948350B2 (en) 2018-09-05 2021-03-16 East Carolina University Systems for detecting vascular and arterial disease in asymptomatic patients and related methods
WO2020081651A1 (en) 2018-10-16 2020-04-23 Activ Surgical, Inc. Autonomous methods and systems for tying surgical knots
US20210015991A1 (en) * 2018-10-19 2021-01-21 PatenSee Ltd. Systems and methods for monitoring the functionality of a blood vessel
EP3903165A4 (en) 2018-12-28 2023-01-25 Activ Surgical, Inc. SYSTEMS AND METHODS TO OPTIMIZE AVAILABILITY, WORKPLACE AND SKILL IN MINIMALLY INVASIVE SURGERY
WO2020140042A1 (en) 2018-12-28 2020-07-02 Activ Surgical, Inc. User interface elements for orientation of remote camera during surgery
US11986266B2 (en) 2019-01-28 2024-05-21 The General Hospital Corporation Speckle-based image distortion correction for laser scanning microscopy
EP3945986A1 (en) 2019-03-26 2022-02-09 East Carolina University Near-infrared fluorescence imaging for blood flow and perfusion visualization and related systems and computer program products
KR20220021920A (ko) 2019-04-08 2022-02-22 액티브 서지컬, 인크. 의료 이미징을 위한 시스템 및 방법
US12292564B2 (en) 2019-04-08 2025-05-06 Activ Surgical, Inc. Systems and methods for medical imaging
WO2020214821A1 (en) 2019-04-19 2020-10-22 Activ Surgical, Inc. Systems and methods for trocar kinematics
EP3987481B1 (en) * 2019-06-18 2025-09-17 SurgVision GmbH Luminescence imaging with refining loop based on combination of partial illuminations
WO2021035094A1 (en) 2019-08-21 2021-02-25 Activ Surgical, Inc. Systems and methods for medical imaging
CN115243610A (zh) 2020-01-08 2022-10-25 艾科缇弗外科公司 激光散斑力反馈估计
EP4090924A4 (en) * 2020-01-14 2024-01-31 University of South Florida Integrated detection scheme for fast blood flow measurement
CN111899262B (zh) * 2020-09-08 2023-11-21 上海交通大学 一种用于内窥镜的实时血流量获取方法、装置
US12064293B2 (en) 2020-10-02 2024-08-20 Cilag Gmbh International Field programmable surgical visualization system
US11877897B2 (en) 2020-10-02 2024-01-23 Cilag Gmbh International Situational awareness of instruments location and individualization of users to control displays
EP3977934A1 (en) * 2020-10-02 2022-04-06 Koninklijke Philips N.V. Systems and methods for performing blood flow velocity measurements
US11963683B2 (en) 2020-10-02 2024-04-23 Cilag Gmbh International Method for operating tiered operation modes in a surgical system
US11830602B2 (en) 2020-10-02 2023-11-28 Cilag Gmbh International Surgical hub having variable interconnectivity capabilities
US12472032B2 (en) 2020-10-02 2025-11-18 Cilag Gmbh International Monitoring of user visual gaze to control which display system displays the primary information
US11748924B2 (en) 2020-10-02 2023-09-05 Cilag Gmbh International Tiered system display control based on capacity and user operation
US12213801B2 (en) 2020-10-02 2025-02-04 Cilag Gmbh International Surgical visualization and particle trend analysis system
US20220104713A1 (en) * 2020-10-02 2022-04-07 Ethicon Llc Tiered-access surgical visualization system
US12484897B2 (en) 2020-10-02 2025-12-02 Cilag Gmbh International Surgical instrument with adaptive configuration control
US11672534B2 (en) 2020-10-02 2023-06-13 Cilag Gmbh International Communication capability of a smart stapler
CA3200540A1 (en) 2020-12-04 2022-06-09 Bogdan MITREA Systems and methods for providing surgical guidance
KR102496066B1 (ko) * 2021-04-08 2023-02-07 주식회사 더웨이브톡 수질 검사기
US12134450B2 (en) 2021-09-08 2024-11-05 Brunswick Corporation Propulsion devices having electric motors for marine vessels and methods for making the same
US12201396B2 (en) 2021-09-10 2025-01-21 Rockley Photonics Limited Optical speckle receiver
US12390117B2 (en) 2021-11-16 2025-08-19 Rockley Photonics Limited Optical sensor module for speckleplethysmography (SPG) and photoplethysmography (PPG)
JPWO2023190382A1 (enExample) * 2022-03-29 2023-10-05
CN118052757B (zh) * 2022-11-14 2025-11-25 中国科学院理化技术研究所 用于观测心肌血流灌注规律的方法及装置
CN116735390A (zh) * 2022-12-17 2023-09-12 北京强度环境研究所 一种管路振动试验截面载荷非接触式高速测试方法
US12396648B1 (en) 2024-11-27 2025-08-26 Rockley Photonics Limited Wearable device with light source and optical sensor
US12484796B1 (en) 2024-11-27 2025-12-02 Rockley Photonics Limited System and method for measuring pulse wave velocity
CN119606350B (zh) * 2024-12-12 2025-09-16 深圳大学 基于神经形态视觉传感器的定量激光散斑血流成像方法

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4541433A (en) 1984-06-01 1985-09-17 Medtronic, Inc. Cardiac output monitor
DE69011158T2 (de) 1989-03-06 1995-01-12 Kowa Co Gerät zur Diagnostik in der Augenheilkunde.
EP0392744B1 (en) 1989-04-10 1995-03-01 Kowa Company Ltd. Ophthalmological measurement method and apparatus
JPH02268727A (ja) 1989-04-10 1990-11-02 Kowa Co 眼科測定方法及び装置
JPH0428348A (ja) 1990-05-24 1992-01-30 Hitoshi Fujii 血流状態画像化装置
US5161531A (en) 1990-09-14 1992-11-10 Duke University Method and apparatus for intravascularly measuring oxidative metabolism in body organs and tissues
JP3035336B2 (ja) 1990-11-27 2000-04-24 興和株式会社 血流測定装置
JP3021628B2 (ja) 1990-11-27 2000-03-15 興和株式会社 血流測定装置
DE19506484C2 (de) 1995-02-24 1999-09-16 Stiftung Fuer Lasertechnologie Verfahren und Vorrichtung zur selektiven nichtinvasiven Lasermyographie (LMG)
US5692510A (en) 1995-09-07 1997-12-02 Technion Research And Development Foundation Ltd. Determining coronary blood flow by cardiac thermography in open chest conditions
US5860922A (en) 1995-09-07 1999-01-19 Technion Research And Development Foundation Ltd. Determining blood flow by measurement of temperature
US5588436A (en) 1995-10-11 1996-12-31 Cook Pacemaker Corporation Pulsed doppler probe
JPH10290791A (ja) 1997-04-18 1998-11-04 Advance Co Ltd レーザー血流計
US20050182434A1 (en) 2000-08-11 2005-08-18 National Research Council Of Canada Method and apparatus for performing intra-operative angiography
US6915154B1 (en) 1999-09-24 2005-07-05 National Research Council Of Canada Method and apparatus for performing intra-operative angiography
US6458086B1 (en) 2000-04-05 2002-10-01 Kenneth Lawrence Franco Implantable blood flow monitoring system
AU2001286424A1 (en) 2000-08-16 2002-02-25 Cook Vascular Incorporated Doppler probe with shapeable portion
US6537223B1 (en) 2000-09-05 2003-03-25 Medi-Stim As Probe head
US7231243B2 (en) 2000-10-30 2007-06-12 The General Hospital Corporation Optical methods for tissue analysis
DE10059070C1 (de) 2000-11-28 2002-02-14 Pulsion Medical Sys Ag Vorrichtung zur Bestimmung von Gewebeperfusion und intraoperative Verwendung
JP5076203B2 (ja) 2001-06-21 2012-11-21 学校法人日本大学 血管疾患検査装置およびバイパス血管診断装置
ATE438109T1 (de) 2001-10-02 2009-08-15 B K Medical As Verfahren und vorrichtung zur geschwindigkeitsschätzung bei synthetischer aperturabbildung
US7113817B1 (en) 2001-10-04 2006-09-26 Wintec, Llc Optical imaging of blood circulation velocities
US6766188B2 (en) 2001-10-15 2004-07-20 University Of Massachusetts Tissue oxygen measurement system
CA2413483A1 (en) 2001-12-26 2003-06-26 Kevin R. Forrester Motion measuring device
EP1332718A1 (en) 2002-02-01 2003-08-06 Stichting Voor De Technische Wetenschappen Laser doppler perfusion imaging using a CMOS image sensor
US6922580B2 (en) 2002-06-04 2005-07-26 Koninklijke Philips Electronics N.V. Blood flow gated MRI
US7404640B2 (en) 2002-06-14 2008-07-29 Physical Sciences, Inc. Monitoring blood flow in the retina using a line-scanning laser ophthalmoscope
JP3490433B1 (ja) 2003-06-02 2004-01-26 株式会社サイバーファーム 生体情報監視システム
KR100634499B1 (ko) 2004-01-12 2006-10-13 삼성전자주식회사 생체광자 측정을 통한 혈류 측정 장치 및 방법
JP4995720B2 (ja) 2004-07-02 2012-08-08 ザ ジェネラル ホスピタル コーポレイション ダブルクラッドファイバを有する内視鏡撮像プローブ
WO2006021096A1 (en) 2004-08-23 2006-03-02 Robarts Research Institute Determination of hemodynamic parameters
JP4649147B2 (ja) * 2004-08-31 2011-03-09 株式会社東芝 超音波診断装置
JP4855423B2 (ja) 2005-02-10 2012-01-18 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 血流センサ
JP4767551B2 (ja) 2005-02-14 2011-09-07 セイコーインスツル株式会社 血液レオロジー測定装置および血液レオロジー計測方法
WO2006111909A1 (en) 2005-04-20 2006-10-26 Cvl Cosmetics S.A. Instrument and method for high-speed perfusion imaging
JPWO2007080743A1 (ja) 2006-01-16 2009-06-11 国立大学法人 北海道大学 検査システムおよび検査方法
US7468039B2 (en) 2006-06-02 2008-12-23 Cook Vascular Incorporated Adjustable tension cuff assembly
US7995814B2 (en) * 2006-06-26 2011-08-09 California Institute Of Technology Dynamic motion contrast and transverse flow estimation using optical coherence tomography
EP2079363B1 (en) 2006-10-30 2020-06-10 Elfi-Tech Ltd Method for in vivo measurement of biological parameters
WO2008069062A1 (ja) * 2006-12-01 2008-06-12 Kyushu Tlo Company, Limited 血流速度画像化装置
WO2008116010A1 (en) * 2007-03-19 2008-09-25 The General Hospital Corporation System and method for providing noninvasive diagnosis of compartment syndrome exemplary laser speckle imaging procedure
US10534129B2 (en) 2007-03-30 2020-01-14 The General Hospital Corporation System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
US7541602B2 (en) 2007-06-04 2009-06-02 Or-Nim Medical Ltd. System and method for noninvasively monitoring conditions of a subject
US9226661B2 (en) 2007-07-06 2016-01-05 Industrial Research Limited Laser speckle imaging systems and methods
IL184868A0 (en) * 2007-07-26 2008-03-20 Univ Bar Ilan Motion detection system and method
US9066686B2 (en) 2008-07-10 2015-06-30 Novadaq Technologies Inc. Functional optical coherent imaging
JP5322548B2 (ja) 2008-09-17 2013-10-23 株式会社東芝 Ｘ線ｃｔ装置、医用画像処理装置および医用画像処理プログラム
CN101485565B (zh) * 2009-02-13 2011-04-13 华中科技大学 一种激光散斑血流成像分析方法
WO2010096453A1 (en) * 2009-02-17 2010-08-26 Board Of Regents, The University Of Texas System Methods of producing laser speckle contrast images
WO2010096447A2 (en) * 2009-02-17 2010-08-26 Board Of Regents, The University Of Texas System Quantitative imaging with multi-exposure speckle imaging (mesi)
US9028421B2 (en) 2009-05-13 2015-05-12 Kyushu Institute Of Technology Blood flow image diagnosing device
CN102860827B (zh) 2009-09-18 2017-05-17 东芝医疗系统株式会社 磁共振成像装置以及磁共振成像方法
JP5689662B2 (ja) * 2009-12-09 2015-03-25 株式会社東芝 超音波診断装置、超音波画像処理装置、超音波画像処理プログラム、医用画像診断装置、医用画像処理装置及び医用画像処理プログラム
US9510758B2 (en) 2010-10-27 2016-12-06 The General Hospital Corporation Apparatus, systems and methods for measuring blood pressure within at least one vessel
WO2012096878A2 (en) 2011-01-10 2012-07-19 East Carolina University Methods, systems and computer program products for non-invasive determination of blood flow distribution using speckle imaging techniques and hemodynamic modeling
CN102429650B (zh) * 2011-11-10 2013-09-25 华中科技大学 一种激光散斑血流成像衬比分析方法

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