CA2900002C - Methods and compositions for the diagnosis of alzheimer's disease - Google Patents
Methods and compositions for the diagnosis of alzheimer's disease Download PDFInfo
- Publication number
- CA2900002C CA2900002C CA2900002A CA2900002A CA2900002C CA 2900002 C CA2900002 C CA 2900002C CA 2900002 A CA2900002 A CA 2900002A CA 2900002 A CA2900002 A CA 2900002A CA 2900002 C CA2900002 C CA 2900002C
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- alpha
- complement
- apolipoprotein
- protein
- additional biomarker
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Classifications
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q2600/112—Disease subtyping, staging or classification
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
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- Epidemiology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1303936.7 | 2013-03-05 | ||
| GB1303936.7A GB2511525A (en) | 2013-03-05 | 2013-03-05 | Methods and Compositions for the Diagnosis of Alzheimer's Disease |
| PCT/EP2014/054185 WO2014135546A1 (en) | 2013-03-05 | 2014-03-04 | Methods and compositions for the diagnosis of alzheimer's disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2900002A1 CA2900002A1 (en) | 2014-09-12 |
| CA2900002C true CA2900002C (en) | 2022-01-25 |
Family
ID=48142456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2900002A Active CA2900002C (en) | 2013-03-05 | 2014-03-04 | Methods and compositions for the diagnosis of alzheimer's disease |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20160097780A1 (enExample) |
| EP (1) | EP2965090B1 (enExample) |
| JP (1) | JP6430413B2 (enExample) |
| CN (1) | CN105164536B (enExample) |
| AU (1) | AU2014224727B2 (enExample) |
| CA (1) | CA2900002C (enExample) |
| ES (1) | ES2674526T3 (enExample) |
| GB (1) | GB2511525A (enExample) |
| WO (1) | WO2014135546A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201504432D0 (en) * | 2015-03-17 | 2015-04-29 | Electrophoretics Ltd | Materials and methods for diagnosis and treatment of alzheimers disease |
| JP6702836B2 (ja) * | 2016-09-28 | 2020-06-03 | ハルメク・ベンチャーズ株式会社 | 認知症判定得点算出装置及びそのプログラム |
| EP3309550A1 (en) * | 2016-10-12 | 2018-04-18 | sphingotec GmbH | Method for the detection of apolipoprotein e4 |
| WO2019086555A1 (en) * | 2017-10-31 | 2019-05-09 | Ge Healthcare Limited | Medical system for diagnosing cognitive disease pathology and/or outcome |
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| JP7109499B2 (ja) * | 2020-05-07 | 2022-07-29 | 一般社団法人脳と心の健康科学研究所 | 認知症判定得点算出装置及びそのプログラム |
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| ITMI20120865A1 (it) * | 2012-05-18 | 2013-11-19 | Antonio Bertolotto | Biomarcatori per patologie del sistema nervoso centrale |
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| AU2014224727A1 (en) | 2015-08-13 |
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| ES2674526T3 (es) | 2018-07-02 |
| CN105164536B (zh) | 2018-02-06 |
| AU2014224727B2 (en) | 2020-09-03 |
| EP2965090A1 (en) | 2016-01-13 |
| GB2511525A (en) | 2014-09-10 |
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