CA2898324A1 - Rapid identification of optimized combinations of input parameters for a complex system - Google Patents

Rapid identification of optimized combinations of input parameters for a complex system Download PDF

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Publication number
CA2898324A1
CA2898324A1 CA2898324A CA2898324A CA2898324A1 CA 2898324 A1 CA2898324 A1 CA 2898324A1 CA 2898324 A CA2898324 A CA 2898324A CA 2898324 A CA2898324 A CA 2898324A CA 2898324 A1 CA2898324 A1 CA 2898324A1
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CA
Canada
Prior art keywords
complex system
drugs
input parameters
tests
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2898324A
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English (en)
French (fr)
Inventor
Chih-Ming Ho
Xianting DING
Ieong Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California San Diego UCSD filed Critical University of California San Diego UCSD
Publication of CA2898324A1 publication Critical patent/CA2898324A1/en
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10—Complex mathematical operations
    • G06F17/11—Complex mathematical operations for solving equations, e.g. nonlinear equations, general mathematical optimization problems
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F30/00—Computer-aided design [CAD]
    • G06F30/20—Design optimisation, verification or simulation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/70—Machine learning, data mining or chemometrics
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F2119/00—Details relating to the type or aim of the analysis or the optimisation
    • G06F2119/22—Yield analysis or yield optimisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/20—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Data Mining & Analysis (AREA)
  • General Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Mathematical Physics (AREA)
  • Databases & Information Systems (AREA)
  • General Health & Medical Sciences (AREA)
  • Mathematical Analysis (AREA)
  • Pure & Applied Mathematics (AREA)
  • Public Health (AREA)
  • Mathematical Optimization (AREA)
  • Computational Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Software Systems (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Computation (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Algebra (AREA)
  • Operations Research (AREA)
  • Computing Systems (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Artificial Intelligence (AREA)
  • Physiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Computer Hardware Design (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Geometry (AREA)
CA2898324A 2013-01-17 2014-01-17 Rapid identification of optimized combinations of input parameters for a complex system Abandoned CA2898324A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361753842P 2013-01-17 2013-01-17
US61/753,842 2013-01-17
PCT/US2014/012111 WO2014113714A1 (en) 2013-01-17 2014-01-17 Rapid identification of optimized combinations of input parameters for a complex system

Publications (1)

Publication Number Publication Date
CA2898324A1 true CA2898324A1 (en) 2014-07-24

Family

ID=51210107

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2898324A Abandoned CA2898324A1 (en) 2013-01-17 2014-01-17 Rapid identification of optimized combinations of input parameters for a complex system

Country Status (9)

Country Link
US (2) US20150356269A1 (enExample)
EP (1) EP2946263A4 (enExample)
JP (3) JP2016507105A (enExample)
KR (1) KR102272849B1 (enExample)
CN (1) CN104981752A (enExample)
AU (2) AU2014207327A1 (enExample)
CA (1) CA2898324A1 (enExample)
SG (1) SG11201505579TA (enExample)
WO (1) WO2014113714A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11986819B2 (en) * 2016-04-13 2024-05-21 Skillcell Method for the preparation of biosynthetic device and their uses in diagnostics
WO2021014343A1 (en) * 2019-07-23 2021-01-28 Reagene Innovations Pvt. Ltd. Artificial intelligence guided identification of affordable re-purposed drugs for leukemias
EP4046161A4 (en) * 2019-10-18 2023-11-29 National University of Singapore METHOD FOR PREDICTING APPROPRIATE THERAPY

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4368509A (en) * 1979-08-24 1983-01-11 Li Chou H Self-optimizing machine and method
JPH11154170A (ja) * 1997-11-20 1999-06-08 Oki Electric Ind Co Ltd 回路シミュレータ
US7124031B1 (en) * 2000-05-11 2006-10-17 Medco Health Solutions, Inc. System for monitoring regulation of pharmaceuticals from data structure of medical and labortory records
US20020165762A1 (en) * 2001-05-02 2002-11-07 Clinical Discovery Israel Ltd. Method for integrated analysis of safety, efficacy and business aspects of drugs undergoing development
US20040009536A1 (en) * 2001-07-30 2004-01-15 George Grass System and method for predicting adme/tox characteristics of a compound
US20040138826A1 (en) * 2002-09-06 2004-07-15 Carter Walter Hansbrough Experimental design and data analytical methods for detecting and characterizing interactions and interaction thresholds on fixed ratio rays of polychemical mixtures and subsets thereof
AU2003269395A1 (en) * 2002-09-16 2004-04-30 Optimata, Ltd. An interactive technique for optimizing drug development from the pre-clinical phases through phase-iv
JP3987059B2 (ja) * 2004-07-30 2007-10-03 株式会社東芝 最適値探索支援装置、最適値探索支援方法、及び記録媒体
JP2007041784A (ja) * 2005-08-02 2007-02-15 Toshiba Corp 最適値探索支援装置、最適値探索支援方法、及びプログラム
JP4670826B2 (ja) * 2007-03-26 2011-04-13 トヨタ自動車株式会社 制御パラメータの実験計画設定方法、その実験計画設定方法をコンピュータに実行させるためのプログラム、およびそのプログラムを記録したコンピュータ読取可能な記録媒体
MX2009010534A (es) * 2007-03-30 2009-12-01 9898 Ltd Tecnologia de plataforma farmaceutica para el desarollo de productos naturales.
SG177938A1 (en) * 2008-03-26 2012-02-28 Theranos Inc Methods and systems for assessing clinical outcomes
KR101013940B1 (ko) * 2009-11-12 2011-02-14 주식회사 자연인 방풍통성산 한약재로부터 방향성 물질을 추출하는 방법
US20130041683A1 (en) * 2010-04-07 2013-02-14 Novacare Computer based system for predicting treatment outcomes
US20120078521A1 (en) * 2010-09-27 2012-03-29 General Electric Company Apparatus, system and methods for assessing drug efficacy using holistic analysis and visualization of pharmacological data

Also Published As

Publication number Publication date
JP2016507105A (ja) 2016-03-07
EP2946263A4 (en) 2016-08-31
KR102272849B1 (ko) 2021-07-02
JP2019029027A (ja) 2019-02-21
AU2014207327A1 (en) 2015-08-06
US20210358636A1 (en) 2021-11-18
SG11201505579TA (en) 2015-08-28
EP2946263A1 (en) 2015-11-25
KR20150110567A (ko) 2015-10-02
WO2014113714A1 (en) 2014-07-24
JP2022048275A (ja) 2022-03-25
US20150356269A1 (en) 2015-12-10
CN104981752A (zh) 2015-10-14
AU2019257388A1 (en) 2019-11-14

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20190115

FZDE Discontinued

Effective date: 20210831