CA2897189C - Model-based personalization scheme of an artificial pancreas for type i diabetes applications - Google Patents
Model-based personalization scheme of an artificial pancreas for type i diabetes applications Download PDFInfo
- Publication number
- CA2897189C CA2897189C CA2897189A CA2897189A CA2897189C CA 2897189 C CA2897189 C CA 2897189C CA 2897189 A CA2897189 A CA 2897189A CA 2897189 A CA2897189 A CA 2897189A CA 2897189 C CA2897189 C CA 2897189C
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- CA
- Canada
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- controller
- model
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- insulin
- basal
- Prior art date
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- Active
Links
- 210000000496 pancreas Anatomy 0.000 title claims abstract description 20
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 title claims description 20
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims abstract description 148
- 102000004877 Insulin Human genes 0.000 claims abstract description 74
- 108090001061 Insulin Proteins 0.000 claims abstract description 74
- 229940125396 insulin Drugs 0.000 claims abstract description 74
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 46
- 239000008103 glucose Substances 0.000 claims description 46
- 239000008280 blood Substances 0.000 claims description 35
- 210000004369 blood Anatomy 0.000 claims description 34
- 230000002218 hypoglycaemic effect Effects 0.000 claims description 18
- 238000004422 calculation algorithm Methods 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 14
- 238000013461 design Methods 0.000 claims description 13
- 230000001610 euglycemic effect Effects 0.000 claims description 8
- 206010022489 Insulin Resistance Diseases 0.000 claims description 7
- 235000012054 meals Nutrition 0.000 description 16
- 208000013016 Hypoglycemia Diseases 0.000 description 13
- 238000012937 correction Methods 0.000 description 12
- 238000004364 calculation method Methods 0.000 description 11
- 238000011161 development Methods 0.000 description 9
- 238000013459 approach Methods 0.000 description 8
- 238000002347 injection Methods 0.000 description 8
- 239000007924 injection Substances 0.000 description 8
- 238000007920 subcutaneous administration Methods 0.000 description 8
- 238000004088 simulation Methods 0.000 description 7
- 230000002503 metabolic effect Effects 0.000 description 6
- 230000009471 action Effects 0.000 description 5
- 238000000126 in silico method Methods 0.000 description 5
- 230000006872 improvement Effects 0.000 description 4
- 230000000291 postprandial effect Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 102000040945 Transcription factor Human genes 0.000 description 3
- 108091023040 Transcription factor Proteins 0.000 description 3
- 150000001720 carbohydrates Chemical class 0.000 description 3
- 235000014633 carbohydrates Nutrition 0.000 description 3
- 201000001421 hyperglycemia Diseases 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- -1 Humalog insulin analog Chemical class 0.000 description 2
- 108010065920 Insulin Lispro Proteins 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 230000002641 glycemic effect Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 229940038661 humalog Drugs 0.000 description 2
- 230000003345 hyperglycaemic effect Effects 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 239000004026 insulin derivative Substances 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 201000004569 Blindness Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 208000001380 Diabetic Ketoacidosis Diseases 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 206010044565 Tremor Diseases 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 238000013528 artificial neural network Methods 0.000 description 1
- 230000002238 attenuated effect Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 208000010643 digestive system disease Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/022—Artificial gland structures using bioreactors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
- A61M2005/1726—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure the body parameters being measured at, or proximate to, the infusion site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
Landscapes
- Health & Medical Sciences (AREA)
- Transplantation (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- External Artificial Organs (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361751941P | 2013-01-14 | 2013-01-14 | |
| US61/751,941 | 2013-01-14 | ||
| PCT/US2014/011360 WO2014110538A1 (en) | 2013-01-14 | 2014-01-13 | Model-based personalization scheme of an artificial pancreas for type i diabetes applications |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2897189A1 CA2897189A1 (en) | 2014-07-17 |
| CA2897189C true CA2897189C (en) | 2017-09-05 |
Family
ID=51167293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2897189A Active CA2897189C (en) | 2013-01-14 | 2014-01-13 | Model-based personalization scheme of an artificial pancreas for type i diabetes applications |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US10413664B2 (enExample) |
| EP (1) | EP2943149B1 (enExample) |
| JP (2) | JP2016506775A (enExample) |
| KR (1) | KR102211352B1 (enExample) |
| AU (1) | AU2014205120B2 (enExample) |
| CA (1) | CA2897189C (enExample) |
| WO (2) | WO2014109898A1 (enExample) |
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| US8417311B2 (en) | 2008-09-12 | 2013-04-09 | Optiscan Biomedical Corporation | Fluid component analysis system and method for glucose monitoring and control |
| US7959598B2 (en) | 2008-08-20 | 2011-06-14 | Asante Solutions, Inc. | Infusion pump systems and methods |
| US9292010B2 (en) * | 2012-11-05 | 2016-03-22 | Rockwell Automation Technologies, Inc. | Online integration of model-based optimization and model-less control |
| WO2014109898A1 (en) * | 2013-01-14 | 2014-07-17 | The Regents Of University Of California | Model-based personalization scheme of an artificial pancreas for type i diabetes applications |
| US9561324B2 (en) | 2013-07-19 | 2017-02-07 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
| GB2523989B (en) | 2014-01-30 | 2020-07-29 | Insulet Netherlands B V | Therapeutic product delivery system and method of pairing |
| CN104749954B (zh) * | 2015-02-08 | 2017-04-12 | 北京化工大学 | 基于内模控制策略的智能灰箱控制系统装置及控制方法 |
| AU2016219961B2 (en) | 2015-02-18 | 2020-07-02 | Insulet Corporation | Fluid delivery and infusion devices, and methods of use thereof |
| HK1257246A1 (zh) | 2016-01-13 | 2019-10-18 | Bigfoot Biomedical, Inc. | 糖尿病管理系统的用户界面 |
| HK1256995A1 (zh) | 2016-01-14 | 2019-10-11 | Bigfoot Biomedical, Inc. | 药物输送设备、系统和方法中的阻塞解决方案 |
| US10307538B2 (en) | 2016-01-14 | 2019-06-04 | Bigfoot Biomedical, Inc. | Adjusting insulin delivery rates |
| US12383166B2 (en) | 2016-05-23 | 2025-08-12 | Insulet Corporation | Insulin delivery system and methods with risk-based set points |
| WO2018058041A1 (en) | 2016-09-23 | 2018-03-29 | Insulet Corporation | Fluid delivery device with sensor |
| US11096624B2 (en) | 2016-12-12 | 2021-08-24 | Bigfoot Biomedical, Inc. | Alarms and alerts for medication delivery devices and systems |
| EP3568860B1 (en) | 2017-01-13 | 2025-12-10 | Insulet Corporation | Insulin delivery methods, systems and devices |
| US10758675B2 (en) | 2017-01-13 | 2020-09-01 | Bigfoot Biomedical, Inc. | System and method for adjusting insulin delivery |
| US10881793B2 (en) | 2017-01-13 | 2021-01-05 | Bigfoot Biomedical, Inc. | System and method for adjusting insulin delivery |
| US11027063B2 (en) | 2017-01-13 | 2021-06-08 | Bigfoot Biomedical, Inc. | Insulin delivery methods, systems and devices |
| US10500334B2 (en) | 2017-01-13 | 2019-12-10 | Bigfoot Biomedical, Inc. | System and method for adjusting insulin delivery |
| EP3398558A1 (en) | 2017-05-02 | 2018-11-07 | Carlo Andretta | In body perfusion system |
| CN116531603A (zh) | 2017-05-05 | 2023-08-04 | 伊莱利利公司 | 生理葡萄糖的闭环控制 |
| EP3438858A1 (en) | 2017-08-02 | 2019-02-06 | Diabeloop | Closed-loop blood glucose control systems and methods |
| JP7133625B2 (ja) | 2017-12-21 | 2022-09-08 | イーライ リリー アンド カンパニー | 生理的グルコースの閉ループ制御 |
| USD928199S1 (en) | 2018-04-02 | 2021-08-17 | Bigfoot Biomedical, Inc. | Medication delivery device with icons |
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| CA3103479A1 (en) | 2018-06-22 | 2019-12-26 | Eli Lilly And Company | Insulin and pramlintide delivery systems, methods, and devices |
| CN109116738B (zh) * | 2018-09-27 | 2021-04-13 | 杭州电子科技大学 | 一种工业加热炉的二自由度内模控制分析方法 |
| CN112789070A (zh) | 2018-09-28 | 2021-05-11 | 英赛罗公司 | 人造胰腺系统的活动模式 |
| US11565039B2 (en) | 2018-10-11 | 2023-01-31 | Insulet Corporation | Event detection for drug delivery system |
| USD920343S1 (en) | 2019-01-09 | 2021-05-25 | Bigfoot Biomedical, Inc. | Display screen or portion thereof with graphical user interface associated with insulin delivery |
| KR102788429B1 (ko) | 2019-05-02 | 2025-03-27 | 삼성전자주식회사 | 개인화된 생체 정보 보정 장치 및 방법 |
| US11801344B2 (en) | 2019-09-13 | 2023-10-31 | Insulet Corporation | Blood glucose rate of change modulation of meal and correction insulin bolus quantity |
| US11935637B2 (en) | 2019-09-27 | 2024-03-19 | Insulet Corporation | Onboarding and total daily insulin adaptivity |
| EP4069082B1 (en) | 2019-12-06 | 2024-06-05 | Insulet Corporation | Techniques and devices providing adaptivity and personalization in diabetes treatment |
| US11833329B2 (en) | 2019-12-20 | 2023-12-05 | Insulet Corporation | Techniques for improved automatic drug delivery performance using delivery tendencies from past delivery history and use patterns |
| AU2021206190A1 (en) | 2020-01-06 | 2022-08-18 | Insulet Corporation | Prediction of meal and/or exercise events based on persistent residuals |
| EP4100958A1 (en) | 2020-02-03 | 2022-12-14 | Insulet Corporation | Use of fuzzy logic in predicting user behavior affecting blood glucose concentration |
| US11551802B2 (en) | 2020-02-11 | 2023-01-10 | Insulet Corporation | Early meal detection and calorie intake detection |
| US11547800B2 (en) | 2020-02-12 | 2023-01-10 | Insulet Corporation | User parameter dependent cost function for personalized reduction of hypoglycemia and/or hyperglycemia in a closed loop artificial pancreas system |
| US11986630B2 (en) | 2020-02-12 | 2024-05-21 | Insulet Corporation | Dual hormone delivery system for reducing impending hypoglycemia and/or hyperglycemia risk |
| US11324889B2 (en) | 2020-02-14 | 2022-05-10 | Insulet Corporation | Compensation for missing readings from a glucose monitor in an automated insulin delivery system |
| US12495994B2 (en) | 2020-02-20 | 2025-12-16 | Insulet Corporation | Meal bolus subcategories in model based insulin therapy |
| US11607493B2 (en) | 2020-04-06 | 2023-03-21 | Insulet Corporation | Initial total daily insulin setting for user onboarding |
| US12121700B2 (en) | 2020-07-22 | 2024-10-22 | Insulet Corporation | Open-loop insulin delivery basal parameters based on insulin delivery records |
| US11684716B2 (en) | 2020-07-31 | 2023-06-27 | Insulet Corporation | Techniques to reduce risk of occlusions in drug delivery systems |
| WO2022072618A1 (en) | 2020-09-30 | 2022-04-07 | Insulet Corporation | Secure wireless communications between a glucose monitor and other devices |
| US12128215B2 (en) | 2020-09-30 | 2024-10-29 | Insulet Corporation | Drug delivery device with integrated optical-based glucose monitor |
| CN112398401B (zh) * | 2020-10-29 | 2022-03-29 | 上海大学 | 一种基于参数失配的低开关频率多步模型预测控制方法 |
| US11160925B1 (en) | 2021-01-29 | 2021-11-02 | Insulet Corporation | Automatic drug delivery system for delivery of a GLP-1 therapeutic |
| US11904140B2 (en) | 2021-03-10 | 2024-02-20 | Insulet Corporation | Adaptable asymmetric medicament cost component in a control system for medicament delivery |
| US12431229B2 (en) | 2021-03-10 | 2025-09-30 | Insulet Corporation | Medicament delivery device with an adjustable and piecewise analyte level cost component to address persistent positive analyte level excursions |
| US20220331520A1 (en) * | 2021-04-20 | 2022-10-20 | Insulet Corporation | Automatic drug delivery system for individuals with type-2 diabetes |
| US20220351820A1 (en) * | 2021-05-01 | 2022-11-03 | Christopher Richard Wilson | Method for determining glucose-dependent insulin sensitivity factors |
| US12496398B2 (en) | 2021-05-28 | 2025-12-16 | Insulet Corporation | Threshold based automatic glucose control response |
| US12406760B2 (en) | 2021-06-07 | 2025-09-02 | Insulet Corporation | Exercise safety prediction based on physiological conditions |
| US12514980B2 (en) | 2021-06-30 | 2026-01-06 | Insulet Corporation | Adjustment of medicament delivery by a medicament delivery device based on menstrual cycle phase |
| US12521486B2 (en) | 2021-07-16 | 2026-01-13 | Insulet Corporation | Method for modification of insulin delivery during pregnancy in automatic insulin delivery systems |
| US11738144B2 (en) | 2021-09-27 | 2023-08-29 | Insulet Corporation | Techniques enabling adaptation of parameters in aid systems by user input |
| WO2023070245A1 (en) * | 2021-10-25 | 2023-05-04 | Medtrum Technologies Inc. | Closed-loop artificial pancreas insulin infusion control system |
| CN116020007B (zh) * | 2021-10-25 | 2025-11-25 | 上海移宇科技股份有限公司 | 闭环人工胰腺胰岛素输注控制系统 |
| CN116020006B (zh) * | 2021-10-25 | 2025-12-23 | 上海移宇科技股份有限公司 | 闭环人工胰腺胰岛素输注控制系统 |
| US11439754B1 (en) | 2021-12-01 | 2022-09-13 | Insulet Corporation | Optimizing embedded formulations for drug delivery |
| WO2024147928A1 (en) | 2023-01-06 | 2024-07-11 | Insulet Corporation | Automatically or manually initiated meal bolus delivery with subsequent automatic safety constraint relaxation |
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| US7806886B2 (en) | 1999-06-03 | 2010-10-05 | Medtronic Minimed, Inc. | Apparatus and method for controlling insulin infusion with state variable feedback |
| US6572545B2 (en) * | 2000-09-22 | 2003-06-03 | Knobbe, Lim & Buckingham | Method and apparatus for real-time control of physiological parameters |
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| US6544212B2 (en) * | 2001-07-31 | 2003-04-08 | Roche Diagnostics Corporation | Diabetes management system |
| US8114023B2 (en) * | 2006-07-28 | 2012-02-14 | Legacy Emanuel Hospital & Health Center | Analyte sensing and response system |
| EP4276851A3 (en) | 2007-06-21 | 2024-01-24 | University Of Virginia Patent Foundation | Lqg artificial pancreas control system and related method |
| KR20120047841A (ko) * | 2009-02-26 | 2012-05-14 | 몰 리서치 어플리케이션스 엘티디 | 당뇨병 관련 치료의 자동 감시를 위한 방법 및 시스템 |
| GR1007310B (el) * | 2009-03-09 | 2011-06-10 | Αχιλλεας Τσουκαλης | Εμφυτευσιμος βιοαισθητηρας με αυτοματη βαθμονομηση |
| AU2010239138B2 (en) * | 2009-04-20 | 2016-01-21 | University Of Technology, Sydney | A method and system for determining a variation in a metabolic function and managing the variation accordingly |
| WO2010138848A1 (en) * | 2009-05-29 | 2010-12-02 | University Of Virginia Patent Foundation | System coordinator and modular architecture for open-loop and closed-loop control of diabetes |
| CA2789630C (en) * | 2010-02-11 | 2016-12-13 | The Regents Of The University Of California | Systems, devices and methods to deliver biological factors or drugs to a subject |
| US9907909B2 (en) * | 2012-12-20 | 2018-03-06 | Animas Corporation | Method and system for a hybrid control-to-target and control-to-range model predictive control of an artificial pancreas |
| WO2014109898A1 (en) * | 2013-01-14 | 2014-07-17 | The Regents Of University Of California | Model-based personalization scheme of an artificial pancreas for type i diabetes applications |
-
2013
- 2013-12-22 WO PCT/US2013/077363 patent/WO2014109898A1/en not_active Ceased
-
2014
- 2014-01-13 CA CA2897189A patent/CA2897189C/en active Active
- 2014-01-13 EP EP14737937.4A patent/EP2943149B1/en active Active
- 2014-01-13 JP JP2015552868A patent/JP2016506775A/ja not_active Withdrawn
- 2014-01-13 KR KR1020157021705A patent/KR102211352B1/ko active Active
- 2014-01-13 AU AU2014205120A patent/AU2014205120B2/en active Active
- 2014-01-13 WO PCT/US2014/011360 patent/WO2014110538A1/en not_active Ceased
-
2015
- 2015-07-06 US US14/792,524 patent/US10413664B2/en active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| KR102211352B1 (ko) | 2021-02-03 |
| WO2014109898A1 (en) | 2014-07-17 |
| JP6914907B2 (ja) | 2021-08-04 |
| JP2016506775A (ja) | 2016-03-07 |
| US20220105270A1 (en) | 2022-04-07 |
| US11197955B2 (en) | 2021-12-14 |
| EP2943149A1 (en) | 2015-11-18 |
| KR20150108862A (ko) | 2015-09-30 |
| US20150306314A1 (en) | 2015-10-29 |
| AU2014205120B2 (en) | 2019-10-17 |
| EP2943149A4 (en) | 2016-08-17 |
| CA2897189A1 (en) | 2014-07-17 |
| AU2014205120A1 (en) | 2015-07-23 |
| US20200078516A1 (en) | 2020-03-12 |
| EP2943149B1 (en) | 2020-09-30 |
| US12102796B2 (en) | 2024-10-01 |
| US20240366873A1 (en) | 2024-11-07 |
| US10413664B2 (en) | 2019-09-17 |
| JP2019055258A (ja) | 2019-04-11 |
| WO2014110538A1 (en) | 2014-07-17 |
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