AU2014205120B2 - Model-based personalization scheme of an artificial pancreas for type I diabetes applications - Google Patents

Model-based personalization scheme of an artificial pancreas for type I diabetes applications Download PDF

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Publication number
AU2014205120B2
AU2014205120B2 AU2014205120A AU2014205120A AU2014205120B2 AU 2014205120 B2 AU2014205120 B2 AU 2014205120B2 AU 2014205120 A AU2014205120 A AU 2014205120A AU 2014205120 A AU2014205120 A AU 2014205120A AU 2014205120 B2 AU2014205120 B2 AU 2014205120B2
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Australia
Prior art keywords
controller
insulin
subject
model
basal
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AU2014205120A
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English (en)
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AU2014205120A1 (en
Inventor
Francis J. Doyle Iii
Dassau EYAL
Joon Book LEE
Dale E. Seborg
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University of California San Diego UCSD
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University of California
University of California San Diego UCSD
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/022—Artificial gland structures using bioreactors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A61M2005/1726—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure the body parameters being measured at, or proximate to, the infusion site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient

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  • Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • External Artificial Organs (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2014205120A 2013-01-14 2014-01-13 Model-based personalization scheme of an artificial pancreas for type I diabetes applications Active AU2014205120B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361751941P 2013-01-14 2013-01-14
US61/751,941 2013-01-14
PCT/US2014/011360 WO2014110538A1 (en) 2013-01-14 2014-01-13 Model-based personalization scheme of an artificial pancreas for type i diabetes applications

Publications (2)

Publication Number Publication Date
AU2014205120A1 AU2014205120A1 (en) 2015-07-23
AU2014205120B2 true AU2014205120B2 (en) 2019-10-17

Family

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AU2014205120A Active AU2014205120B2 (en) 2013-01-14 2014-01-13 Model-based personalization scheme of an artificial pancreas for type I diabetes applications

Country Status (7)

Country Link
US (4) US10413664B2 (enExample)
EP (1) EP2943149B1 (enExample)
JP (2) JP2016506775A (enExample)
KR (1) KR102211352B1 (enExample)
AU (1) AU2014205120B2 (enExample)
CA (1) CA2897189C (enExample)
WO (2) WO2014109898A1 (enExample)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8417311B2 (en) 2008-09-12 2013-04-09 Optiscan Biomedical Corporation Fluid component analysis system and method for glucose monitoring and control
US7959598B2 (en) 2008-08-20 2011-06-14 Asante Solutions, Inc. Infusion pump systems and methods
US9292010B2 (en) * 2012-11-05 2016-03-22 Rockwell Automation Technologies, Inc. Online integration of model-based optimization and model-less control
WO2014109898A1 (en) * 2013-01-14 2014-07-17 The Regents Of University Of California Model-based personalization scheme of an artificial pancreas for type i diabetes applications
US9561324B2 (en) 2013-07-19 2017-02-07 Bigfoot Biomedical, Inc. Infusion pump system and method
GB2523989B (en) 2014-01-30 2020-07-29 Insulet Netherlands B V Therapeutic product delivery system and method of pairing
CN104749954B (zh) * 2015-02-08 2017-04-12 北京化工大学 基于内模控制策略的智能灰箱控制系统装置及控制方法
AU2016219961B2 (en) 2015-02-18 2020-07-02 Insulet Corporation Fluid delivery and infusion devices, and methods of use thereof
HK1257246A1 (zh) 2016-01-13 2019-10-18 Bigfoot Biomedical, Inc. 糖尿病管理系统的用户界面
HK1256995A1 (zh) 2016-01-14 2019-10-11 Bigfoot Biomedical, Inc. 药物输送设备、系统和方法中的阻塞解决方案
US10307538B2 (en) 2016-01-14 2019-06-04 Bigfoot Biomedical, Inc. Adjusting insulin delivery rates
US12383166B2 (en) 2016-05-23 2025-08-12 Insulet Corporation Insulin delivery system and methods with risk-based set points
WO2018058041A1 (en) 2016-09-23 2018-03-29 Insulet Corporation Fluid delivery device with sensor
US11096624B2 (en) 2016-12-12 2021-08-24 Bigfoot Biomedical, Inc. Alarms and alerts for medication delivery devices and systems
EP3568860B1 (en) 2017-01-13 2025-12-10 Insulet Corporation Insulin delivery methods, systems and devices
US10758675B2 (en) 2017-01-13 2020-09-01 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
US10881793B2 (en) 2017-01-13 2021-01-05 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
US11027063B2 (en) 2017-01-13 2021-06-08 Bigfoot Biomedical, Inc. Insulin delivery methods, systems and devices
US10500334B2 (en) 2017-01-13 2019-12-10 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
EP3398558A1 (en) 2017-05-02 2018-11-07 Carlo Andretta In body perfusion system
CN116531603A (zh) 2017-05-05 2023-08-04 伊莱利利公司 生理葡萄糖的闭环控制
EP3438858A1 (en) 2017-08-02 2019-02-06 Diabeloop Closed-loop blood glucose control systems and methods
JP7133625B2 (ja) 2017-12-21 2022-09-08 イーライ リリー アンド カンパニー 生理的グルコースの閉ループ制御
USD928199S1 (en) 2018-04-02 2021-08-17 Bigfoot Biomedical, Inc. Medication delivery device with icons
US11565043B2 (en) 2018-05-04 2023-01-31 Insulet Corporation Safety constraints for a control algorithm based drug delivery system
CA3103479A1 (en) 2018-06-22 2019-12-26 Eli Lilly And Company Insulin and pramlintide delivery systems, methods, and devices
CN109116738B (zh) * 2018-09-27 2021-04-13 杭州电子科技大学 一种工业加热炉的二自由度内模控制分析方法
CN112789070A (zh) 2018-09-28 2021-05-11 英赛罗公司 人造胰腺系统的活动模式
US11565039B2 (en) 2018-10-11 2023-01-31 Insulet Corporation Event detection for drug delivery system
USD920343S1 (en) 2019-01-09 2021-05-25 Bigfoot Biomedical, Inc. Display screen or portion thereof with graphical user interface associated with insulin delivery
KR102788429B1 (ko) 2019-05-02 2025-03-27 삼성전자주식회사 개인화된 생체 정보 보정 장치 및 방법
US11801344B2 (en) 2019-09-13 2023-10-31 Insulet Corporation Blood glucose rate of change modulation of meal and correction insulin bolus quantity
US11935637B2 (en) 2019-09-27 2024-03-19 Insulet Corporation Onboarding and total daily insulin adaptivity
EP4069082B1 (en) 2019-12-06 2024-06-05 Insulet Corporation Techniques and devices providing adaptivity and personalization in diabetes treatment
US11833329B2 (en) 2019-12-20 2023-12-05 Insulet Corporation Techniques for improved automatic drug delivery performance using delivery tendencies from past delivery history and use patterns
AU2021206190A1 (en) 2020-01-06 2022-08-18 Insulet Corporation Prediction of meal and/or exercise events based on persistent residuals
EP4100958A1 (en) 2020-02-03 2022-12-14 Insulet Corporation Use of fuzzy logic in predicting user behavior affecting blood glucose concentration
US11551802B2 (en) 2020-02-11 2023-01-10 Insulet Corporation Early meal detection and calorie intake detection
US11547800B2 (en) 2020-02-12 2023-01-10 Insulet Corporation User parameter dependent cost function for personalized reduction of hypoglycemia and/or hyperglycemia in a closed loop artificial pancreas system
US11986630B2 (en) 2020-02-12 2024-05-21 Insulet Corporation Dual hormone delivery system for reducing impending hypoglycemia and/or hyperglycemia risk
US11324889B2 (en) 2020-02-14 2022-05-10 Insulet Corporation Compensation for missing readings from a glucose monitor in an automated insulin delivery system
US12495994B2 (en) 2020-02-20 2025-12-16 Insulet Corporation Meal bolus subcategories in model based insulin therapy
US11607493B2 (en) 2020-04-06 2023-03-21 Insulet Corporation Initial total daily insulin setting for user onboarding
US12121700B2 (en) 2020-07-22 2024-10-22 Insulet Corporation Open-loop insulin delivery basal parameters based on insulin delivery records
US11684716B2 (en) 2020-07-31 2023-06-27 Insulet Corporation Techniques to reduce risk of occlusions in drug delivery systems
WO2022072618A1 (en) 2020-09-30 2022-04-07 Insulet Corporation Secure wireless communications between a glucose monitor and other devices
US12128215B2 (en) 2020-09-30 2024-10-29 Insulet Corporation Drug delivery device with integrated optical-based glucose monitor
CN112398401B (zh) * 2020-10-29 2022-03-29 上海大学 一种基于参数失配的低开关频率多步模型预测控制方法
US11160925B1 (en) 2021-01-29 2021-11-02 Insulet Corporation Automatic drug delivery system for delivery of a GLP-1 therapeutic
US11904140B2 (en) 2021-03-10 2024-02-20 Insulet Corporation Adaptable asymmetric medicament cost component in a control system for medicament delivery
US12431229B2 (en) 2021-03-10 2025-09-30 Insulet Corporation Medicament delivery device with an adjustable and piecewise analyte level cost component to address persistent positive analyte level excursions
US20220331520A1 (en) * 2021-04-20 2022-10-20 Insulet Corporation Automatic drug delivery system for individuals with type-2 diabetes
US20220351820A1 (en) * 2021-05-01 2022-11-03 Christopher Richard Wilson Method for determining glucose-dependent insulin sensitivity factors
US12496398B2 (en) 2021-05-28 2025-12-16 Insulet Corporation Threshold based automatic glucose control response
US12406760B2 (en) 2021-06-07 2025-09-02 Insulet Corporation Exercise safety prediction based on physiological conditions
US12514980B2 (en) 2021-06-30 2026-01-06 Insulet Corporation Adjustment of medicament delivery by a medicament delivery device based on menstrual cycle phase
US12521486B2 (en) 2021-07-16 2026-01-13 Insulet Corporation Method for modification of insulin delivery during pregnancy in automatic insulin delivery systems
US11738144B2 (en) 2021-09-27 2023-08-29 Insulet Corporation Techniques enabling adaptation of parameters in aid systems by user input
WO2023070245A1 (en) * 2021-10-25 2023-05-04 Medtrum Technologies Inc. Closed-loop artificial pancreas insulin infusion control system
CN116020007B (zh) * 2021-10-25 2025-11-25 上海移宇科技股份有限公司 闭环人工胰腺胰岛素输注控制系统
CN116020006B (zh) * 2021-10-25 2025-12-23 上海移宇科技股份有限公司 闭环人工胰腺胰岛素输注控制系统
US11439754B1 (en) 2021-12-01 2022-09-13 Insulet Corporation Optimizing embedded formulations for drug delivery
WO2024147928A1 (en) 2023-01-06 2024-07-11 Insulet Corporation Automatically or manually initiated meal bolus delivery with subsequent automatic safety constraint relaxation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120123234A1 (en) * 2009-02-26 2012-05-17 Eran Atlas Method and system for automatic monitoring of diabetes related treatments

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7806886B2 (en) 1999-06-03 2010-10-05 Medtronic Minimed, Inc. Apparatus and method for controlling insulin infusion with state variable feedback
US6572545B2 (en) * 2000-09-22 2003-06-03 Knobbe, Lim & Buckingham Method and apparatus for real-time control of physiological parameters
US7460130B2 (en) * 2000-09-26 2008-12-02 Advantage 3D Llc Method and system for generation, storage and distribution of omni-directional object views
US6544212B2 (en) * 2001-07-31 2003-04-08 Roche Diagnostics Corporation Diabetes management system
US8114023B2 (en) * 2006-07-28 2012-02-14 Legacy Emanuel Hospital & Health Center Analyte sensing and response system
EP4276851A3 (en) 2007-06-21 2024-01-24 University Of Virginia Patent Foundation Lqg artificial pancreas control system and related method
GR1007310B (el) * 2009-03-09 2011-06-10 Αχιλλεας Τσουκαλης Εμφυτευσιμος βιοαισθητηρας με αυτοματη βαθμονομηση
AU2010239138B2 (en) * 2009-04-20 2016-01-21 University Of Technology, Sydney A method and system for determining a variation in a metabolic function and managing the variation accordingly
WO2010138848A1 (en) * 2009-05-29 2010-12-02 University Of Virginia Patent Foundation System coordinator and modular architecture for open-loop and closed-loop control of diabetes
CA2789630C (en) * 2010-02-11 2016-12-13 The Regents Of The University Of California Systems, devices and methods to deliver biological factors or drugs to a subject
US9907909B2 (en) * 2012-12-20 2018-03-06 Animas Corporation Method and system for a hybrid control-to-target and control-to-range model predictive control of an artificial pancreas
WO2014109898A1 (en) * 2013-01-14 2014-07-17 The Regents Of University Of California Model-based personalization scheme of an artificial pancreas for type i diabetes applications

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120123234A1 (en) * 2009-02-26 2012-05-17 Eran Atlas Method and system for automatic monitoring of diabetes related treatments

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Alessia Tagliavini, "Development and evaluation of pid controllers for glucose control in people with type 1 diabetes mellitus", (20120716), URL: http://tesi.cab.unipd.it/40204/, (20160708) *
VAN HEUSDEN, K. ET AL., "Control-Relevant Models for Glucose Control Using A Priori Patient Characteristics", IEEE TRANS. BIO. ENG., (2012), vol. 59, pages 1839 - 1849 *

Also Published As

Publication number Publication date
KR102211352B1 (ko) 2021-02-03
WO2014109898A1 (en) 2014-07-17
JP6914907B2 (ja) 2021-08-04
JP2016506775A (ja) 2016-03-07
US20220105270A1 (en) 2022-04-07
US11197955B2 (en) 2021-12-14
EP2943149A1 (en) 2015-11-18
KR20150108862A (ko) 2015-09-30
US20150306314A1 (en) 2015-10-29
EP2943149A4 (en) 2016-08-17
CA2897189A1 (en) 2014-07-17
AU2014205120A1 (en) 2015-07-23
US20200078516A1 (en) 2020-03-12
EP2943149B1 (en) 2020-09-30
US12102796B2 (en) 2024-10-01
US20240366873A1 (en) 2024-11-07
US10413664B2 (en) 2019-09-17
JP2019055258A (ja) 2019-04-11
CA2897189C (en) 2017-09-05
WO2014110538A1 (en) 2014-07-17

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