CA2892859A1 - Combination therapy for treating her2-positive cancers - Google Patents
Combination therapy for treating her2-positive cancers Download PDFInfo
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- CA2892859A1 CA2892859A1 CA2892859A CA2892859A CA2892859A1 CA 2892859 A1 CA2892859 A1 CA 2892859A1 CA 2892859 A CA2892859 A CA 2892859A CA 2892859 A CA2892859 A CA 2892859A CA 2892859 A1 CA2892859 A1 CA 2892859A1
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- her2
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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- C—CHEMISTRY; METALLURGY
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
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| US201261732736P | 2012-12-03 | 2012-12-03 | |
| US61/732,736 | 2012-12-03 | ||
| US201361810254P | 2013-04-09 | 2013-04-09 | |
| US61/810,254 | 2013-04-09 | ||
| PCT/US2013/072941 WO2014089127A1 (en) | 2012-12-03 | 2013-12-03 | Combination therapy for treating her2-positive cancers |
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| CA2892859A1 true CA2892859A1 (en) | 2014-06-12 |
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| CA2892859A Abandoned CA2892859A1 (en) | 2012-12-03 | 2013-12-03 | Combination therapy for treating her2-positive cancers |
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| EP (1) | EP2925361A4 (enExample) |
| JP (1) | JP2016501234A (enExample) |
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| CN105050619A (zh) | 2012-12-03 | 2015-11-11 | 梅里马克制药公司 | 用于治疗her2-阳性癌症的组合疗法 |
| US9861633B2 (en) * | 2013-07-17 | 2018-01-09 | Foundation Medicine, Inc. | Methods of treating urothelial carcinoma |
| US20160045596A1 (en) * | 2014-08-05 | 2016-02-18 | Merrimack Pharmaceuticals, Inc. | Combination therapies for treating her2-positive cancers that are resistant to her2-targeted therapies |
| WO2017136770A1 (en) * | 2016-02-05 | 2017-08-10 | Merrimack Pharmaceuticals, Inc. | Treatment of her2-intermediate cancer |
| KR102646046B1 (ko) * | 2017-01-06 | 2024-03-08 | 바이오션, 인코포레이티드 | Erbb2 항체 및 이의 용도 |
| CN115957321A (zh) * | 2023-03-03 | 2023-04-14 | 盛禾(中国)生物制药有限公司 | 一种抗her2抗体在制备治疗癌症的药物中的用途 |
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| JPH0720857B2 (ja) | 1988-08-11 | 1995-03-08 | テルモ株式会社 | リポソームおよびその製法 |
| US6214388B1 (en) | 1994-11-09 | 2001-04-10 | The Regents Of The University Of California | Immunoliposomes that optimize internalization into target cells |
| US6210707B1 (en) | 1996-11-12 | 2001-04-03 | The Regents Of The University Of California | Methods of forming protein-linked lipidic microparticles, and compositions thereof |
| US7244826B1 (en) | 1998-04-24 | 2007-07-17 | The Regents Of The University Of California | Internalizing ERB2 antibodies |
| US20050084524A1 (en) | 1998-09-30 | 2005-04-21 | Alza Corporation | Method for potentiating activity of a chemotherapeutic drug |
| US20020151508A1 (en) * | 2001-02-09 | 2002-10-17 | Schering Corporation | Methods for treating proliferative diseases |
| ZA200507752B (en) | 2003-03-28 | 2007-01-31 | Threshold Pharmaceuticals Inc | Compositions and methods for treating cancer |
| GB0326486D0 (en) | 2003-11-14 | 2003-12-17 | Pharma Mar Sau | Combination treatment |
| US7674456B2 (en) | 2004-06-14 | 2010-03-09 | Charles Wiseman | Breast cancer cell lines and uses thereof |
| KR20200058588A (ko) * | 2005-01-21 | 2020-05-27 | 제넨테크, 인크. | Her 항체의 고정 용량 투여법 |
| JP2008536944A (ja) | 2005-04-22 | 2008-09-11 | アルザ・コーポレーシヨン | Her2細胞受容体を標的とするためのイムノリポソーム組成物 |
| JP5185813B2 (ja) * | 2005-04-26 | 2013-04-17 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 癌免疫治療のための組成物および方法 |
| BRPI0808055A2 (pt) | 2007-02-16 | 2013-07-30 | Merrimack Pharmaceuticals Inc | anticorpo monoclonal isolado ou porÇço do mesmo que se liga ao antÍgeno, composiÇço, Ácido nucleico isolado, vetor de expressço, cÉlula hospedeira, hibridoma, kit, uso de um anticorpo monoclonal isolado ou porÇço do mesmo que se liga ao antÍgeno, mÉtodo para diagnosticar um cÂncer associado com erbb3 em um paciente, e, anticorpo |
| CA2700810A1 (en) | 2007-09-28 | 2009-04-02 | Universitatsspital Basel | Immunoliposomes for treatment of cancer |
| EA022201B1 (ru) | 2008-04-11 | 2015-11-30 | Мерримак Фармасьютикалз, Инк. | Агент, способный связываться с опухолевой клеткой, содержащий линкер на основе hsa, и его применение |
| US8927694B2 (en) | 2008-11-18 | 2015-01-06 | Merrimack Pharmaceuticals, Inc. | Human serum albumin linkers and conjugates thereof |
| CN107252417A (zh) * | 2010-12-06 | 2017-10-17 | 梅里麦克制药股份有限公司 | 在使用包含蒽环类化疗剂的erbb2靶向免疫脂质体的治疗中防止心肌毒性的剂量和给药 |
| US20120231066A1 (en) | 2011-01-24 | 2012-09-13 | Henry John Smith | Multi-drug liposomes to treat tumors |
| CN105050619A (zh) | 2012-12-03 | 2015-11-11 | 梅里马克制药公司 | 用于治疗her2-阳性癌症的组合疗法 |
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Also Published As
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| CN105050619A (zh) | 2015-11-11 |
| CN107412163A (zh) | 2017-12-01 |
| MX2015006931A (es) | 2016-07-05 |
| US20160250328A1 (en) | 2016-09-01 |
| EP2925361A1 (en) | 2015-10-07 |
| KR20150091116A (ko) | 2015-08-07 |
| US9913901B2 (en) | 2018-03-13 |
| WO2014089127A1 (en) | 2014-06-12 |
| AU2013355337B2 (en) | 2018-07-12 |
| JP2016501234A (ja) | 2016-01-18 |
| EP2925361A4 (en) | 2016-06-29 |
| HK1214955A1 (zh) | 2016-08-12 |
| SG11201504293WA (en) | 2015-06-29 |
| AU2013355337A1 (en) | 2015-07-09 |
| IL239031A0 (en) | 2015-07-30 |
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| FZDE | Discontinued |
Effective date: 20191203 |