CA2885940A1 - Cyclic depsipeptide compounds and their uses - Google Patents
Cyclic depsipeptide compounds and their uses Download PDFInfo
- Publication number
- CA2885940A1 CA2885940A1 CA2885940A CA2885940A CA2885940A1 CA 2885940 A1 CA2885940 A1 CA 2885940A1 CA 2885940 A CA2885940 A CA 2885940A CA 2885940 A CA2885940 A CA 2885940A CA 2885940 A1 CA2885940 A1 CA 2885940A1
- Authority
- CA
- Canada
- Prior art keywords
- meleu
- alkyl
- optionally substituted
- leu
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- OHRURASPPZQGQM-GCCNXGTGSA-N romidepsin Chemical class O1C(=O)[C@H](C(C)C)NC(=O)C(=C/C)/NC(=O)[C@H]2CSSCC\C=C\[C@@H]1CC(=O)N[C@H](C(C)C)C(=O)N2 OHRURASPPZQGQM-GCCNXGTGSA-N 0.000 title abstract description 4
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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Landscapes
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1217560.0 | 2012-10-02 | ||
| GBGB1217560.0A GB201217560D0 (en) | 2012-10-02 | 2012-10-02 | Novel cyclic depsipeptide compounds and their uses |
| PCT/GB2013/052570 WO2014053834A1 (en) | 2012-10-02 | 2013-10-02 | Cyclic depsipeptide compounds and their uses |
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| Publication Number | Publication Date |
|---|---|
| CA2885940A1 true CA2885940A1 (en) | 2014-04-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2885940A Abandoned CA2885940A1 (en) | 2012-10-02 | 2013-10-02 | Cyclic depsipeptide compounds and their uses |
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| Country | Link |
|---|---|
| US (3) | US9382295B2 (enExample) |
| EP (1) | EP2904001A1 (enExample) |
| JP (1) | JP6263541B2 (enExample) |
| CN (1) | CN104768968B (enExample) |
| AU (1) | AU2013326231B2 (enExample) |
| CA (1) | CA2885940A1 (enExample) |
| GB (1) | GB201217560D0 (enExample) |
| WO (1) | WO2014053834A1 (enExample) |
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|---|---|---|---|---|
| WO2016112321A1 (en) * | 2015-01-08 | 2016-07-14 | Allergan, Inc. | Cyclosporin derivatives wherein the mebmt sidechain has been cyclized |
| US11046730B2 (en) | 2016-04-15 | 2021-06-29 | The Regents Of The University Of California | Antimicrobial compositions |
| CN111449050A (zh) | 2019-01-20 | 2020-07-28 | 睿诺医疗科技（上海）有限公司 | 环孢菌素类似物及其用途 |
| CN109821020B (zh) * | 2019-01-28 | 2021-07-30 | 温州医科大学 | 一种制备干眼症药物的应用及治疗干眼症的方法 |
| KR20220080181A (ko) | 2019-10-12 | 2022-06-14 | 파사이트 메디컬 테크놀로지 (상하이) 컴퍼니 리미티드 | 신독소-유도된 신장 손상의 치료 및 예방 |
| PE20221323A1 (es) * | 2019-11-07 | 2022-09-09 | Chugai Pharmaceutical Co Ltd | Compuesto de peptidos ciclicos que tiene accion inhibidora de kras |
| BR112022018929A2 (pt) | 2020-03-26 | 2022-12-06 | Farsight Medical Tech Shanghai Co Ltd | Inibidores da ciclofilina e seus usos |
| US12465629B2 (en) | 2020-04-15 | 2025-11-11 | Farsight Medical Technology (Shanghai) Co., Ltd. | Prevention and treatment of organ injuries |
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| ATE110784T1 (de) * | 1987-06-19 | 1994-09-15 | Sandoz Ag | Zyklische peptolide. |
| US5595756A (en) * | 1993-12-22 | 1997-01-21 | Inex Pharmaceuticals Corporation | Liposomal compositions for enhanced retention of bioactive agents |
| ES2387682T3 (es) | 2005-01-10 | 2012-09-28 | Debiopharm S.A. | Utilización de un undecapéptido cíclico para la preparación de un medicamento administrable durante situaciones isquémicas miocárdicas |
| MX2011004881A (es) * | 2008-11-06 | 2011-08-12 | Debio Rech Pharma Sa | Compuestos cicloundecadepsipeptidos y el uso de dichos compuestos como un medicamento. |
| US8623814B2 (en) * | 2010-02-23 | 2014-01-07 | Enanta Pharmaceuticals, Inc. | Antiviral agents |
| WO2011141891A1 (en) | 2010-05-12 | 2011-11-17 | Debio Recherche Pharmaceutique S.A. | Use of cycloundecadepsipeptide compounds |
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2012
- 2012-10-02 GB GBGB1217560.0A patent/GB201217560D0/en not_active Ceased
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2013
- 2013-10-02 WO PCT/GB2013/052570 patent/WO2014053834A1/en not_active Ceased
- 2013-10-02 CA CA2885940A patent/CA2885940A1/en not_active Abandoned
- 2013-10-02 CN CN201380056072.1A patent/CN104768968B/zh not_active Expired - Fee Related
- 2013-10-02 EP EP13771583.5A patent/EP2904001A1/en not_active Withdrawn
- 2013-10-02 US US14/433,327 patent/US9382295B2/en not_active Expired - Fee Related
- 2013-10-02 JP JP2015533704A patent/JP6263541B2/ja not_active Expired - Fee Related
- 2013-10-02 AU AU2013326231A patent/AU2013326231B2/en not_active Ceased
-
2016
- 2016-06-20 US US15/187,039 patent/US9895412B2/en active Active
-
2018
- 2018-01-29 US US15/882,510 patent/US20180153958A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20170007664A1 (en) | 2017-01-12 |
| US20150259386A1 (en) | 2015-09-17 |
| US20180153958A1 (en) | 2018-06-07 |
| US9895412B2 (en) | 2018-02-20 |
| GB201217560D0 (en) | 2012-11-14 |
| US9382295B2 (en) | 2016-07-05 |
| AU2013326231A1 (en) | 2015-04-09 |
| CN104768968B (zh) | 2019-04-05 |
| CN104768968A (zh) | 2015-07-08 |
| JP6263541B2 (ja) | 2018-01-17 |
| JP2016500653A (ja) | 2016-01-14 |
| AU2013326231B2 (en) | 2017-06-29 |
| EP2904001A1 (en) | 2015-08-12 |
| WO2014053834A1 (en) | 2014-04-10 |
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