GB201217560D0 - Novel cyclic depsipeptide compounds and their uses - Google Patents

Novel cyclic depsipeptide compounds and their uses

Info

Publication number
GB201217560D0
GB201217560D0 GBGB1217560.0A GB201217560A GB201217560D0 GB 201217560 D0 GB201217560 D0 GB 201217560D0 GB 201217560 A GB201217560 A GB 201217560A GB 201217560 D0 GB201217560 D0 GB 201217560D0
Authority
GB
United Kingdom
Prior art keywords
novel cyclic
cyclic depsipeptide
depsipeptide compounds
compounds
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1217560.0A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SELCIA PHARMA LIMITED
Original Assignee
MITOPHARM Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MITOPHARM Ltd filed Critical MITOPHARM Ltd
Priority to GBGB1217560.0A priority Critical patent/GB201217560D0/en
Publication of GB201217560D0 publication Critical patent/GB201217560D0/en
Priority to CN201380056072.1A priority patent/CN104768968B/zh
Priority to AU2013326231A priority patent/AU2013326231B2/en
Priority to CA2885940A priority patent/CA2885940A1/en
Priority to JP2015533704A priority patent/JP6263541B2/ja
Priority to PCT/GB2013/052570 priority patent/WO2014053834A1/en
Priority to US14/433,327 priority patent/US9382295B2/en
Priority to EP13771583.5A priority patent/EP2904001A1/en
Priority to US15/187,039 priority patent/US9895412B2/en
Priority to US15/882,510 priority patent/US20180153958A1/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
GBGB1217560.0A 2012-10-02 2012-10-02 Novel cyclic depsipeptide compounds and their uses Ceased GB201217560D0 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
GBGB1217560.0A GB201217560D0 (en) 2012-10-02 2012-10-02 Novel cyclic depsipeptide compounds and their uses
EP13771583.5A EP2904001A1 (en) 2012-10-02 2013-10-02 Cyclic depsipeptide compounds and their uses
JP2015533704A JP6263541B2 (ja) 2012-10-02 2013-10-02 環状デプシペプチド化合物およびそれらの用途
AU2013326231A AU2013326231B2 (en) 2012-10-02 2013-10-02 Cyclic depsipeptide compounds and their uses
CA2885940A CA2885940A1 (en) 2012-10-02 2013-10-02 Cyclic depsipeptide compounds and their uses
CN201380056072.1A CN104768968B (zh) 2012-10-02 2013-10-02 环状缩酚肽化合物及其用途
PCT/GB2013/052570 WO2014053834A1 (en) 2012-10-02 2013-10-02 Cyclic depsipeptide compounds and their uses
US14/433,327 US9382295B2 (en) 2012-10-02 2013-10-02 Cyclic depsipeptide compounds and their uses
US15/187,039 US9895412B2 (en) 2012-10-02 2016-06-20 Cyclic depsipeptide compounds and their uses
US15/882,510 US20180153958A1 (en) 2012-10-02 2018-01-29 Cyclic depsipeptide compounds and their uses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1217560.0A GB201217560D0 (en) 2012-10-02 2012-10-02 Novel cyclic depsipeptide compounds and their uses

Publications (1)

Publication Number Publication Date
GB201217560D0 true GB201217560D0 (en) 2012-11-14

Family

ID=47225510

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1217560.0A Ceased GB201217560D0 (en) 2012-10-02 2012-10-02 Novel cyclic depsipeptide compounds and their uses

Country Status (8)

Country Link
US (3) US9382295B2 (enExample)
EP (1) EP2904001A1 (enExample)
JP (1) JP6263541B2 (enExample)
CN (1) CN104768968B (enExample)
AU (1) AU2013326231B2 (enExample)
CA (1) CA2885940A1 (enExample)
GB (1) GB201217560D0 (enExample)
WO (1) WO2014053834A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201639873A (zh) 2015-01-08 2016-11-16 歐樂根公司 Ｍｅｂｍｔ側鏈已環化之環孢菌素衍生物
US11046730B2 (en) 2016-04-15 2021-06-29 The Regents Of The University Of California Antimicrobial compositions
CN111449050A (zh) 2019-01-20 2020-07-28 睿诺医疗科技（上海）有限公司 环孢菌素类似物及其用途
CN109821020B (zh) * 2019-01-28 2021-07-30 温州医科大学 一种制备干眼症药物的应用及治疗干眼症的方法
CN116870135A (zh) 2019-10-12 2023-10-13 睿诺医疗科技（上海）有限公司 肾毒素诱发的肾损伤的治疗和预防
EP4043478A4 (en) * 2019-11-07 2024-01-03 Chugai Seiyaku Kabushiki Kaisha CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITING ACTION
CA3172535A1 (en) 2020-03-26 2021-09-30 Ching-Pong Mak Cyclophilin inhibitors and uses thereof
AU2021256222A1 (en) 2020-04-15 2022-10-06 Farsight Medical Technology (Shanghai) Co., Ltd. Prevention and treatment of organ injuries
CN115636872B (zh) * 2022-06-24 2026-02-24 中国农业科学院生物技术研究所 木糖酸肽类化合物及其在抗寄生虫药物中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE110784T1 (de) * 1987-06-19 1994-09-15 Sandoz Ag Zyklische peptolide.
US5595756A (en) * 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
JP2008526816A (ja) 2005-01-10 2008-07-24 デビオファーム ソシエテ アノニム 心筋虚血状態の間の投与のための薬剤の製造のための環状ウンデカペプチドの使用
CN102202679B (zh) * 2008-11-06 2014-05-07 帝柏奥研究制药有限公司 环十一缩酚酸肽化合物及其作为药物的用途
US8623814B2 (en) * 2010-02-23 2014-01-07 Enanta Pharmaceuticals, Inc. Antiviral agents
WO2011141891A1 (en) * 2010-05-12 2011-11-17 Debio Recherche Pharmaceutique S.A. Use of cycloundecadepsipeptide compounds

Also Published As

Publication number Publication date
AU2013326231B2 (en) 2017-06-29
JP2016500653A (ja) 2016-01-14
US9895412B2 (en) 2018-02-20
US20150259386A1 (en) 2015-09-17
CN104768968B (zh) 2019-04-05
CA2885940A1 (en) 2014-04-10
AU2013326231A1 (en) 2015-04-09
EP2904001A1 (en) 2015-08-12
US9382295B2 (en) 2016-07-05
CN104768968A (zh) 2015-07-08
WO2014053834A1 (en) 2014-04-10
US20170007664A1 (en) 2017-01-12
JP6263541B2 (ja) 2018-01-17
US20180153958A1 (en) 2018-06-07

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Legal Events

Date Code Title Description
COOA Change in applicant's name or ownership of the application

Owner name: SELCIA PHARMA LIMITED

Free format text: FORMER OWNER: MITOPHARM LTD

AT Applications terminated before publication under section 16(1)