CA2882705C - Nanoparticle formulation comprising cationic cholesterol derivatives for delivery of short-chain fatty acids - Google Patents
Nanoparticle formulation comprising cationic cholesterol derivatives for delivery of short-chain fatty acids Download PDFInfo
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- CA2882705C CA2882705C CA2882705A CA2882705A CA2882705C CA 2882705 C CA2882705 C CA 2882705C CA 2882705 A CA2882705 A CA 2882705A CA 2882705 A CA2882705 A CA 2882705A CA 2882705 C CA2882705 C CA 2882705C
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- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| GBGB1215289.8A GB201215289D0 (en) | 2012-08-28 | 2012-08-28 | Nanoparticle formulation |
| GB1215289.8 | 2012-08-28 | ||
| PCT/GB2013/052258 WO2014033453A1 (en) | 2012-08-28 | 2013-08-28 | Nanoparticle formulation |
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| CA2882705A1 CA2882705A1 (en) | 2014-03-06 |
| CA2882705C true CA2882705C (en) | 2021-06-22 |
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| CA2882705A Active CA2882705C (en) | 2012-08-28 | 2013-08-28 | Nanoparticle formulation comprising cationic cholesterol derivatives for delivery of short-chain fatty acids |
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| JP (1) | JP6483017B2 (OSRAM) |
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| US8962015B2 (en) | 2007-09-28 | 2015-02-24 | Sdg, Inc. | Orally bioavailable lipid-based constructs |
| US20160158174A1 (en) * | 2014-12-09 | 2016-06-09 | Intercontinental Great Brands Llc | Enteric-Coated Functional Food Ingredients And Methods For Making The Enteric-Coated Functional Food Ingredients |
| RU2017127597A (ru) * | 2015-01-23 | 2019-02-25 | Темпл Юнивёрсити-Оф Дзе Коммонвелс Систем Оф Хайе Эдьюкейшен | Применение короткоцепочечных жирных кислот для профилактики рака |
| CN106551902B (zh) * | 2015-09-17 | 2020-07-03 | 阿赖耶识（上海）生物技术有限公司 | 一种高稳定的非囊泡型纳米颗粒及其在治疗微生物感染中的应用 |
| CN105669964B (zh) * | 2016-03-04 | 2017-11-21 | 博瑞生物医药（苏州）股份有限公司 | 卵巢癌特异靶向的生物可降解双亲性聚合物、由其制备的聚合物囊泡及应用 |
| US11065217B2 (en) | 2017-01-27 | 2021-07-20 | Temple University—Of the Commonwealth System of Higher Education | Use of short chain fatty acids for the treatment and prevention of diseases and disorders |
| US11077173B2 (en) | 2017-03-13 | 2021-08-03 | Sdg, Inc. | Lipid-based nanoparticles and methods using same |
| AU2018236190B2 (en) * | 2017-03-13 | 2025-02-20 | Sdg, Inc. | Lipid-based nanoparticles with enhanced stability |
| CN110891982B (zh) | 2017-04-17 | 2023-12-22 | 芝加哥大学 | 向肠道递送短链脂肪酸以用于人体保健和疾病治疗的聚合物材料 |
| CN107049954A (zh) * | 2017-06-12 | 2017-08-18 | 杭州普施康生物科技有限公司 | 一种药物组合及其制备方法和用途 |
| CN110192651A (zh) * | 2019-05-31 | 2019-09-03 | 浙江工业大学 | 一种利用大豆分离蛋白负载植物甾醇酯的纳米乳液的制备方法 |
| CN111426659B (zh) * | 2020-03-24 | 2023-06-06 | 深圳唯公生物科技有限公司 | 磁性荧光编码微球及其制备方法 |
| US20250269003A1 (en) * | 2022-04-22 | 2025-08-28 | University Of Virginia Patent Foundation | Nano-enhanced vaccine |
| KR20250107214A (ko) * | 2022-11-10 | 2025-07-11 | 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 | 간질환 또는 간장애의 치료 또는 예방 방법 |
| CN118105524B (zh) * | 2024-03-14 | 2024-11-22 | 南京鼓楼医院 | 一种靶向肠上皮细胞的焦亡抑制剂药物递送系统及其制备方法和应用 |
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| US6441025B2 (en) * | 1996-03-12 | 2002-08-27 | Pg-Txl Company, L.P. | Water soluble paclitaxel derivatives |
| DE69727384T2 (de) * | 1996-05-24 | 2004-11-04 | IC-VEC Ltd. | Polykatonische sterin-derivate zur transfektion |
| US6146847A (en) * | 1996-11-01 | 2000-11-14 | Genespan Corporation | Stabilized transient gene expression |
| IT1303787B1 (it) * | 1998-11-25 | 2001-02-23 | Maria Rosa Gasco | "nanosfere lipidiche solide atte ad una rapida internalizzazione nellecellule" |
| EP1140022B8 (en) * | 1998-12-18 | 2008-10-15 | Hadasit Medical Research Services & Development Ltd. | Method of administering a compound to multi-drug resistant cells |
| US6387952B1 (en) | 2000-09-19 | 2002-05-14 | Arco Chemical Technology L.P. | Method of treating gastrointestinal disorders, particularly colitis |
| WO2003030864A1 (en) * | 2001-05-29 | 2003-04-17 | Neopharm, Inc. | Liposomal formulation of irinotecan |
| WO2006007634A1 (en) | 2004-07-16 | 2006-01-26 | Cerylid Biosciences Ltd | Processes and intermediates |
| WO2006076734A2 (en) | 2005-01-14 | 2006-07-20 | Medical College Of Georgia Research Institute | Prodrugs of short-chain fatty acids and treatment methods |
| US9315532B2 (en) | 2005-05-24 | 2016-04-19 | The Johns Hopkins University | Fatty acid carbohydrate hybrid molecules as therapeutic agents and methods thereof |
| ITMI20051024A1 (it) | 2005-06-01 | 2006-12-02 | Maria Rosa Gasco | Nuovo uso di nanoparticelle lipidiche solide |
| US7700567B2 (en) * | 2005-09-29 | 2010-04-20 | Supergen, Inc. | Oligonucleotide analogues incorporating 5-aza-cytosine therein |
| CA2673622A1 (en) | 2006-12-22 | 2008-07-03 | Imuthes Limited | Lipid |
| CA2742689A1 (en) * | 2008-11-17 | 2010-05-20 | Enzon Pharmaceuticals, Inc. | Branched cationic lipids for nucleic acids delivery system |
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| EP2890365A1 (en) | 2015-07-08 |
| GB201215289D0 (en) | 2012-10-10 |
| AU2013308245B2 (en) | 2018-03-29 |
| EP2890365B1 (en) | 2019-11-20 |
| CN104837482A (zh) | 2015-08-12 |
| CN104837482B (zh) | 2018-09-18 |
| AU2013308245A1 (en) | 2015-04-09 |
| JP2015530382A (ja) | 2015-10-15 |
| US20150224054A1 (en) | 2015-08-13 |
| US10201499B2 (en) | 2019-02-12 |
| WO2014033453A1 (en) | 2014-03-06 |
| JP6483017B2 (ja) | 2019-03-13 |
| HK1211862A1 (en) | 2016-06-03 |
| CA2882705A1 (en) | 2014-03-06 |
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