CA2879704A1 - Combination of pi3k inhibitor and c-met inhibitor - Google Patents
Combination of pi3k inhibitor and c-met inhibitor Download PDFInfo
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- CA2879704A1 CA2879704A1 CA2879704A CA2879704A CA2879704A1 CA 2879704 A1 CA2879704 A1 CA 2879704A1 CA 2879704 A CA2879704 A CA 2879704A CA 2879704 A CA2879704 A CA 2879704A CA 2879704 A1 CA2879704 A1 CA 2879704A1
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- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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Landscapes
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- Chemical & Material Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201261683790P | 2012-08-16 | 2012-08-16 | |
| US61/683,790 | 2012-08-16 | ||
| PCT/US2013/054848 WO2014028566A1 (en) | 2012-08-16 | 2013-08-14 | Combination of pi3k inhibitor and c-met inhibitor |
Publications (1)
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| CA2879704A1 true CA2879704A1 (en) | 2014-02-20 |
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| UY34632A (es) | 2012-02-24 | 2013-05-31 | Novartis Ag | Compuestos de oxazolidin- 2- ona y usos de los mismos |
| EP3964513A1 (en) | 2012-04-03 | 2022-03-09 | Novartis AG | Combination products with tyrosine kinase inhibitors and their use |
| US9296733B2 (en) | 2012-11-12 | 2016-03-29 | Novartis Ag | Oxazolidin-2-one-pyrimidine derivative and use thereof for the treatment of conditions, diseases and disorders dependent upon PI3 kinases |
| SG11201507063YA (en) | 2013-03-14 | 2015-10-29 | Novartis Ag | 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant idh |
| CN105338980A (zh) * | 2013-06-18 | 2016-02-17 | 诺华股份有限公司 | 药物组合 |
| AU2014296887A1 (en) | 2013-08-02 | 2016-01-28 | Aduro Biotech Holdings, Europe B.V. | Combining CD27 agonists and immune checkpoint inhibition for immune stimulation |
| SG11201700147SA (en) | 2014-07-25 | 2017-02-27 | Novartis Ag | Tablet formulation of 2-fluoro-n-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide |
| CN108367003B (zh) | 2014-12-12 | 2022-01-21 | 麻省总医院 | 乳腺癌脑转移的治疗 |
| GB201516504D0 (en) | 2015-09-17 | 2015-11-04 | Astrazeneca Ab | Imadazo(4,5-c)quinolin-2-one Compounds and their use in treating cancer |
| US20230065577A1 (en) * | 2019-12-20 | 2023-03-02 | Recurium Ip Holdings, Llc | Combinations |
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| CN104758288A (zh) * | 2007-02-20 | 2015-07-08 | 诺华股份有限公司 | 作为脂质激酶和mTOR双重抑制剂的咪唑并喹啉类 |
| JP2011513364A (ja) * | 2008-03-05 | 2011-04-28 | ノバルティス アーゲー | Ｅｇｆｒ依存性疾患またはｅｇｆｒファミリーメンバーを標的とする薬剤に対して耐性を獲得した疾患を治療するためのピリミジン誘導体の使用 |
| MX368802B (es) * | 2008-05-21 | 2019-10-17 | Incyte Corp | Sales de 2-fluoro-n-metil-4-[7-(quinolin-6-il-metil)-imidazo[1, 2-b][1 ,2, 4]triazin-2-il]benzamida y procesos relacionados con la preparacion de las mismas. |
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| UA104147C2 (uk) * | 2008-09-10 | 2014-01-10 | Новартис Аг | Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань |
| US20100267742A1 (en) * | 2009-04-17 | 2010-10-21 | Rush University Medical Center | Combination targeted therapy for lung cancer |
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- 2013-08-14 WO PCT/US2013/054848 patent/WO2014028566A1/en active Application Filing
- 2013-08-14 HK HK15112283.4A patent/HK1211476A1/xx unknown
- 2013-08-14 CA CA2879704A patent/CA2879704A1/en not_active Abandoned
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2016
- 2016-10-06 AU AU2016238903A patent/AU2016238903A1/en not_active Abandoned
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2017
- 2017-10-18 JP JP2017201774A patent/JP6644042B2/ja active Active
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2018
- 2018-03-09 AU AU2018201725A patent/AU2018201725A1/en not_active Abandoned
- 2018-10-11 US US16/157,333 patent/US20190083500A1/en not_active Abandoned
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2019
- 2019-07-30 US US16/526,027 patent/US20190350935A1/en not_active Abandoned
- 2019-09-05 AU AU2019226212A patent/AU2019226212B2/en not_active Ceased
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2020
- 2020-01-07 JP JP2020000928A patent/JP6970217B2/ja not_active Expired - Fee Related
- 2020-03-17 US US16/820,886 patent/US20200253980A1/en not_active Abandoned
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2021
- 2021-12-15 US US17/644,491 patent/US20220280523A1/en not_active Abandoned
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| FZDE | Discontinued |
Effective date: 20220927 |