CA2877299C - Methods of treating or preventing periodontitis and diseases associated with periodontitis - Google Patents
Methods of treating or preventing periodontitis and diseases associated with periodontitis Download PDFInfo
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- CA2877299C CA2877299C CA2877299A CA2877299A CA2877299C CA 2877299 C CA2877299 C CA 2877299C CA 2877299 A CA2877299 A CA 2877299A CA 2877299 A CA2877299 A CA 2877299A CA 2877299 C CA2877299 C CA 2877299C
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- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
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| PCT/US2013/046599 WO2013192319A1 (en) | 2012-06-20 | 2013-06-19 | Methods of treating or preventing periodontitis and diseases associated with periodontitis |
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| US9579360B2 (en) * | 2012-06-20 | 2017-02-28 | The Trustees Of The University Of Pennsylvania | Methods of treating or preventing periodontitis and diseases associated with periodontitis |
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| KR101981532B1 (ko) | 2014-06-12 | 2019-09-02 | 라 파마슈티컬스 인코포레이티드 | 보체 활성의 조절 |
| PL3250230T3 (pl) | 2015-01-28 | 2022-02-14 | Ra Pharmaceuticals, Inc. | Modulatory aktywności dopełniacza |
| WO2017035405A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amino compounds for treatment of immune and inflammatory disorders |
| EP3340983B1 (en) | 2015-08-26 | 2023-10-04 | Achillion Pharmaceuticals, Inc. | Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders |
| WO2017035401A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amide compounds for treatment of immune and inflammatory disorders |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| RU2733720C2 (ru) | 2015-12-16 | 2020-10-06 | Ра Фармасьютикалз, Инк. | Модуляторы активности комплемента |
| MX2019006527A (es) | 2016-12-07 | 2019-08-01 | Ra Pharmaceuticals Inc | Moduladores de la actividad del complemento. |
| CN110603252A (zh) | 2017-03-01 | 2019-12-20 | 艾其林医药公司 | 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物 |
| WO2018160891A1 (en) | 2017-03-01 | 2018-09-07 | Achillion Pharmaceutical, Inc. | Pharmaceutical compounds for treatment of medical disorders |
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| KR20240167712A (ko) | 2017-12-15 | 2024-11-27 | 아펠리스 파마슈티컬스 인코포레이티드 | 투여 요법 및 관련 조성물 및 방법 |
| HUE057693T2 (hu) | 2018-04-06 | 2022-05-28 | Univ Pennsylvania | Fokozott oldhatóságú és javított farmakokinetikai tulajdonságú kompsztatin analógok |
| US11814391B2 (en) | 2018-09-06 | 2023-11-14 | Achillion Pharmaceuticals, Inc. | Macrocyclic compounds for the treatment of medical disorders |
| MX2021002640A (es) | 2018-09-06 | 2021-07-16 | Achillion Pharmaceuticals Inc | Formas morficas de los inhibidores del factor d del complemento. |
| EP3856164B1 (en) | 2018-09-25 | 2024-08-07 | Achillion Pharmaceuticals, Inc. | Morphic forms of complement factor d inhibitors |
| US12239645B2 (en) | 2018-12-17 | 2025-03-04 | Achillion Pharmaceuticals, Inc. | Targeted dosing for the treatment of complement mediated disorders |
| CN113543796A (zh) | 2019-03-08 | 2021-10-22 | Ra制药公司 | 齐鲁考普作为深层组织穿透性c5抑制剂 |
| JP7635138B2 (ja) | 2019-03-22 | 2025-02-25 | アキリオン ファーマシューティカルズ， インコーポレーテッド | 補体媒介性障害の治療のための医薬化合物 |
| US20230115176A1 (en) | 2019-03-29 | 2023-04-13 | Ra Pharmaceuticals, Inc. | Complement Modulators and Related Methods |
| US20220211799A1 (en) | 2019-04-24 | 2022-07-07 | Ra Pharmaceuticals, Inc. | Compositions and methods for modulating complement activity |
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| JP2001294536A (ja) * | 2000-04-12 | 2001-10-23 | Sunstar Inc | 歯周病予防・治療剤 |
| US20050169921A1 (en) * | 2004-02-03 | 2005-08-04 | Leonard Bell | Method of treating hemolytic disease |
| PT1928454E (pt) * | 2005-05-10 | 2014-12-04 | Intermune Inc | Derivativos da piridona para modulação do sistema de proteína quinase ativada pelo stress |
| EP2148691B1 (en) * | 2007-02-05 | 2015-05-20 | Apellis Pharmaceuticals, Inc. | Compstatin analogues for use in the treatment of inflammatory conditions of the respiratory system |
| WO2010056399A1 (en) * | 2008-11-17 | 2010-05-20 | Incode Biopharmaceutics, Inc. | Method and composition for modulating the immune system and various inflammatory conditions comprising complement depletors |
| ES2655389T3 (es) * | 2009-05-01 | 2018-02-19 | The Trustees Of The University Of Pennsylvania | Compstatina modificada con esqueleto peptídico y modificaciones c-terminales |
| WO2010132954A1 (en) | 2009-05-21 | 2010-11-25 | Oral Health Australia Pty Ltd | Method of treating periodontal disease by administering antagonists of par-2 |
| EP2480536B1 (en) * | 2009-09-23 | 2014-08-13 | The Regents of the University of Colorado, A Body Corporate | Toll-like receptor modulators and uses thereof |
| EP2525814A4 (en) | 2010-01-22 | 2013-09-11 | Univ Louisville Res Found | METHODS OF TREATING OR PREVENTING PERIODONTITIS AND PARODONTIST-RELATED DISEASES |
| US10627412B2 (en) * | 2010-03-17 | 2020-04-21 | Kagoshima University | Periodontal-disease-specific peptide, and treatment and diagnosis of periodontal disease using same |
| CN103796667A (zh) * | 2011-06-22 | 2014-05-14 | 艾普莱斯制药公司 | 用补体抑制剂治疗慢性障碍的方法 |
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| WO2013192319A1 (en) | 2013-12-27 |
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| US20130344082A1 (en) | 2013-12-26 |
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