CA2876903C - Apparatus, system, and method for image normalization using a gaussian residual of fit selection criteria - Google Patents

Apparatus, system, and method for image normalization using a gaussian residual of fit selection criteria Download PDF

Info

Publication number
CA2876903C
CA2876903C CA2876903A CA2876903A CA2876903C CA 2876903 C CA2876903 C CA 2876903C CA 2876903 A CA2876903 A CA 2876903A CA 2876903 A CA2876903 A CA 2876903A CA 2876903 C CA2876903 C CA 2876903C
Authority
CA
Canada
Prior art keywords
calibration
particles
image
intensity
particle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2876903A
Other languages
English (en)
French (fr)
Other versions
CA2876903A1 (en
Inventor
Matthew S. Fisher
Nicolas Arab
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Luminex Corp
Original Assignee
Luminex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Luminex Corp filed Critical Luminex Corp
Publication of CA2876903A1 publication Critical patent/CA2876903A1/en
Application granted granted Critical
Publication of CA2876903C publication Critical patent/CA2876903C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/695—Preprocessing, e.g. image segmentation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1012—Calibrating particle analysers; References therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/693—Acquisition
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/698—Matching; Classification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Multimedia (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Theoretical Computer Science (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Image Analysis (AREA)
  • Image Processing (AREA)
CA2876903A 2012-06-15 2013-06-14 Apparatus, system, and method for image normalization using a gaussian residual of fit selection criteria Active CA2876903C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261660270P 2012-06-15 2012-06-15
US61/660,270 2012-06-15
PCT/US2013/046035 WO2013188857A2 (en) 2012-06-15 2013-06-14 Apparatus, system, and method for image normalization using a gaussian residual of fit selection criteria

Publications (2)

Publication Number Publication Date
CA2876903A1 CA2876903A1 (en) 2013-12-19
CA2876903C true CA2876903C (en) 2020-07-14

Family

ID=49755971

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2876903A Active CA2876903C (en) 2012-06-15 2013-06-14 Apparatus, system, and method for image normalization using a gaussian residual of fit selection criteria

Country Status (6)

Country Link
US (3) US9245169B2 (enExample)
EP (1) EP2861969B1 (enExample)
JP (1) JP6105061B2 (enExample)
CN (1) CN104541152B (enExample)
CA (1) CA2876903C (enExample)
WO (1) WO2013188857A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107407631B (zh) * 2015-02-06 2020-11-03 生命技术公司 用于校准结合染料的系统和方法
GB2571743A (en) * 2018-03-07 2019-09-11 Pop Bio Ltd A method of capturing image data of a luminescent sample and apparatus for the same
CN110361304B (zh) * 2019-06-20 2021-10-01 南开大学 基于pmf3模型和ams数据估算不同生成路径对颗粒物中二次无机粒子贡献的方法
CN116583735A (zh) * 2020-10-30 2023-08-11 贝克顿·迪金森公司 用于表征和编码光检测系统的方法和系统
CN112504934B (zh) * 2020-11-23 2021-09-21 中国水利水电科学研究院 一种混凝土坝渗流渗压预测和监控阈值确定方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3824393A (en) 1971-08-25 1974-07-16 American Express Invest System for differential particle counting
US5981180A (en) 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
EP0852004B1 (en) 1995-10-11 2011-01-19 Luminex Corporation Multiplexed analysis of clinical specimens
US5736330A (en) 1995-10-11 1998-04-07 Luminex Corporation Method and compositions for flow cytometric determination of DNA sequences
US6449562B1 (en) 1996-10-10 2002-09-10 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
IL135593A (en) 1997-10-14 2004-06-01 Luminex Corp Precisely fluorescently painted polymeric microspheres and methods for making and using them
CA2318779C (en) 1998-01-22 2009-08-25 Luminex Corporation Microparticles with multiple fluorescent signals
US6592822B1 (en) 1998-05-14 2003-07-15 Luminex Corporation Multi-analyte diagnostic system and computer implemented process for same
US6376843B1 (en) 1999-06-23 2002-04-23 Evotec Oai Ag Method of characterizing fluorescent molecules or other particles using generating functions
WO2000066985A1 (en) * 1999-04-29 2000-11-09 Evotec Biosystems Ag A method of characterizing fluorescent molecules or other particles using generating functions
EP1208382B1 (en) 1999-08-17 2006-04-26 Luminex Corporation Encapsulation of fluorescent particles
ATE412184T1 (de) 1999-08-17 2008-11-15 Luminex Corp Verfahren zur analyse einer mehrzahl von proben verschiedenen ursprungs auf einen analyten
US7274809B2 (en) * 2002-08-29 2007-09-25 Perceptronix Medical, Inc. And British Columbia Cancer Agency Computerized methods and systems related to the detection of malignancy-associated changes (MAC) to detect cancer
US7175810B2 (en) * 2002-11-15 2007-02-13 Eksigent Technologies Processing of particles
WO2004091386A2 (en) * 2003-04-15 2004-10-28 Philips Intellectual Property & Standards Gmbh Arrangement and method for the spatially resolved determination of state variables in an examination area
CN1524925A (zh) * 2003-09-18 2004-09-01 吉林大学 荧光磁性纳米复合物及其制备方法和应用
US8520205B2 (en) * 2005-02-09 2013-08-27 Flir Systems, Inc. Method and system for detecting, classifying and identifying particles
CA2623130C (en) * 2005-09-21 2018-01-09 Luminex Corporation Methods and systems for image data processing
US8187885B2 (en) 2009-05-07 2012-05-29 Nodality, Inc. Microbead kit and method for quantitative calibration and performance monitoring of a fluorescence instrument
US8767069B2 (en) * 2010-06-30 2014-07-01 Luminex Corporation Apparatus, system, and method for increasing measurement accuracy in a particle imaging device using light distribution
US8274656B2 (en) * 2010-06-30 2012-09-25 Luminex Corporation Apparatus, system, and method for increasing measurement accuracy in a particle imaging device

Also Published As

Publication number Publication date
US20180268191A1 (en) 2018-09-20
US10733418B2 (en) 2020-08-04
WO2013188857A2 (en) 2013-12-19
EP2861969B1 (en) 2022-08-03
JP6105061B2 (ja) 2017-03-29
CN104541152B (zh) 2017-08-25
HK1209482A1 (en) 2016-04-01
US9245169B2 (en) 2016-01-26
CN104541152A (zh) 2015-04-22
CA2876903A1 (en) 2013-12-19
US9984279B2 (en) 2018-05-29
WO2013188857A3 (en) 2014-02-13
US20160232396A1 (en) 2016-08-11
EP2861969A2 (en) 2015-04-22
EP2861969A4 (en) 2016-03-09
JP2015523660A (ja) 2015-08-13
US20130336568A1 (en) 2013-12-19

Similar Documents

Publication Publication Date Title
US10733418B2 (en) Apparatus, system, and method for image normalization using a Gaussian residual of fit selection criteria
EP2588835B1 (en) Apparatus, system, and method for increasing measurement accuracy in a particle imaging device
AU2011279976B2 (en) Apparatus, system, and method for increasing measurement accuracy in a particle imaging device using light distribution
CA2852915C (en) Methods and systems for image data processing
HK1209482B (en) Apparatus, system, and method for image normalization using a gaussian residual of fit selection criteria
HK1185406B (en) Apparatus, system, and method for increasing measurement accuracy in a particle imaging device
HK1185406A (en) Apparatus, system, and method for increasing measurement accuracy in a particle imaging device
HK1185410A (en) System, and method for increasing measurement accuracy in a particle imaging device using light distribution
HK1185410B (en) System, and method for increasing measurement accuracy in a particle imaging device using light distribution
HK1212024B (zh) 用於通過使用光分布來提高粒子成像設備中的測量精確度的裝置、系統和方法

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20180608