CN104541152B - 使用拟合选择标准的高斯残差的图像归一化装置、系统和方法 - Google Patents

使用拟合选择标准的高斯残差的图像归一化装置、系统和方法 Download PDF

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CN104541152B
CN104541152B CN201380031436.0A CN201380031436A CN104541152B CN 104541152 B CN104541152 B CN 104541152B CN 201380031436 A CN201380031436 A CN 201380031436A CN 104541152 B CN104541152 B CN 104541152B
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particles
calibration
channel
intensity
calibration particles
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CN104541152A (zh
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M·S·费希尔
N·阿拉伯
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Luminex Corp
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Luminex Corp
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    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/695—Preprocessing, e.g. image segmentation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1012—Calibrating particle analysers; References therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/693—Acquisition
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/698—Matching; Classification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Multimedia (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Theoretical Computer Science (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Image Analysis (AREA)
  • Image Processing (AREA)
CN201380031436.0A 2012-06-15 2013-06-14 使用拟合选择标准的高斯残差的图像归一化装置、系统和方法 Active CN104541152B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261660270P 2012-06-15 2012-06-15
US61/660,270 2012-06-15
PCT/US2013/046035 WO2013188857A2 (en) 2012-06-15 2013-06-14 Apparatus, system, and method for image normalization using a gaussian residual of fit selection criteria

Publications (2)

Publication Number Publication Date
CN104541152A CN104541152A (zh) 2015-04-22
CN104541152B true CN104541152B (zh) 2017-08-25

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Country Status (6)

Country Link
US (3) US9245169B2 (enExample)
EP (1) EP2861969B1 (enExample)
JP (1) JP6105061B2 (enExample)
CN (1) CN104541152B (enExample)
CA (1) CA2876903C (enExample)
WO (1) WO2013188857A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102370360B1 (ko) * 2015-02-06 2022-03-04 라이프 테크놀로지스 코포레이션 결합 염료를 보정하기 위한 시스템 및 방법
GB2571743A (en) * 2018-03-07 2019-09-11 Pop Bio Ltd A method of capturing image data of a luminescent sample and apparatus for the same
CN110361304B (zh) * 2019-06-20 2021-10-01 南开大学 基于pmf3模型和ams数据估算不同生成路径对颗粒物中二次无机粒子贡献的方法
US20220136956A1 (en) * 2020-10-30 2022-05-05 Becton, Dickinson And Company Method and systems for characterizing and encoding a light detection system
CN112504934B (zh) * 2020-11-23 2021-09-21 中国水利水电科学研究院 一种混凝土坝渗流渗压预测和监控阈值确定方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1175602A1 (en) * 1999-04-29 2002-01-30 Evotec OAI AG A method of characterizing fluorescent molecules or other particles using generating functions
CN1524925A (zh) * 2003-09-18 2004-09-01 吉林大学 荧光磁性纳米复合物及其制备方法和应用
CN1774200A (zh) * 2003-04-15 2006-05-17 皇家飞利浦电子股份有限公司 对检测区域内的状态变量进行空间解像测定的装置及方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3824393A (en) 1971-08-25 1974-07-16 American Express Invest System for differential particle counting
US5981180A (en) 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
WO1997014028A2 (en) 1995-10-11 1997-04-17 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
US5736330A (en) 1995-10-11 1998-04-07 Luminex Corporation Method and compositions for flow cytometric determination of DNA sequences
US6449562B1 (en) 1996-10-10 2002-09-10 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
WO1999019515A1 (en) 1997-10-14 1999-04-22 Luminex Corporation Precision fluorescently dyed particles and methods of making and using same
KR100593712B1 (ko) 1998-01-22 2006-06-30 루미넥스 코포레이션 다수의 형광 시그널을 갖는 마이크로입자
CA2331897C (en) 1998-05-14 2008-11-18 Luminex Corporation Multi-analyte diagnostic system and computer implemented process for same
US6376843B1 (en) 1999-06-23 2002-04-23 Evotec Oai Ag Method of characterizing fluorescent molecules or other particles using generating functions
EP1204869B1 (en) 1999-08-17 2008-10-22 Luminex Corporation Method for analyzing a number of samples from a variety of sources for a single analyte
ATE324588T1 (de) 1999-08-17 2006-05-15 Luminex Corp Verkapselung von fluoreszierenden partikeln
US7274809B2 (en) * 2002-08-29 2007-09-25 Perceptronix Medical, Inc. And British Columbia Cancer Agency Computerized methods and systems related to the detection of malignancy-associated changes (MAC) to detect cancer
US7175810B2 (en) * 2002-11-15 2007-02-13 Eksigent Technologies Processing of particles
AU2006338285B8 (en) * 2005-02-09 2012-11-08 S3I, Llc Method and system for detecting, classifying and identifying particles
CN101268355A (zh) 2005-09-21 2008-09-17 卢米尼克斯股份有限公司 图像数据处理的方法和系统
US8187885B2 (en) * 2009-05-07 2012-05-29 Nodality, Inc. Microbead kit and method for quantitative calibration and performance monitoring of a fluorescence instrument
US8767069B2 (en) * 2010-06-30 2014-07-01 Luminex Corporation Apparatus, system, and method for increasing measurement accuracy in a particle imaging device using light distribution
US8274656B2 (en) * 2010-06-30 2012-09-25 Luminex Corporation Apparatus, system, and method for increasing measurement accuracy in a particle imaging device

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1175602A1 (en) * 1999-04-29 2002-01-30 Evotec OAI AG A method of characterizing fluorescent molecules or other particles using generating functions
CN1774200A (zh) * 2003-04-15 2006-05-17 皇家飞利浦电子股份有限公司 对检测区域内的状态变量进行空间解像测定的装置及方法
CN1524925A (zh) * 2003-09-18 2004-09-01 吉林大学 荧光磁性纳米复合物及其制备方法和应用

Also Published As

Publication number Publication date
CN104541152A (zh) 2015-04-22
WO2013188857A2 (en) 2013-12-19
CA2876903C (en) 2020-07-14
JP6105061B2 (ja) 2017-03-29
US20130336568A1 (en) 2013-12-19
US9245169B2 (en) 2016-01-26
EP2861969B1 (en) 2022-08-03
HK1209482A1 (en) 2016-04-01
EP2861969A4 (en) 2016-03-09
JP2015523660A (ja) 2015-08-13
US10733418B2 (en) 2020-08-04
CA2876903A1 (en) 2013-12-19
WO2013188857A3 (en) 2014-02-13
US9984279B2 (en) 2018-05-29
EP2861969A2 (en) 2015-04-22
US20160232396A1 (en) 2016-08-11
US20180268191A1 (en) 2018-09-20

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