CA2871468C - Lactoferrin fusion protein and method for preparation thereof - Google Patents
Lactoferrin fusion protein and method for preparation thereof Download PDFInfo
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- CA2871468C CA2871468C CA2871468A CA2871468A CA2871468C CA 2871468 C CA2871468 C CA 2871468C CA 2871468 A CA2871468 A CA 2871468A CA 2871468 A CA2871468 A CA 2871468A CA 2871468 C CA2871468 C CA 2871468C
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- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- Health & Medical Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Diabetes (AREA)
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- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
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| JP2012-098085 | 2012-04-23 | ||
| PCT/JP2013/062685 WO2013162050A1 (ja) | 2012-04-23 | 2013-04-23 | ラクトフェリン融合タンパク質及びその製造方法 |
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| CA2871468C true CA2871468C (en) | 2021-09-21 |
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| CA2871468A Active CA2871468C (en) | 2012-04-23 | 2013-04-23 | Lactoferrin fusion protein and method for preparation thereof |
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| KR102177252B1 (ko) | 2012-04-23 | 2020-11-10 | 가부시키가이샤 에스 앤드 케이 바이오파마 | 락토페린 융합 단백질 및 그의 제조방법 |
| KR102461210B1 (ko) * | 2014-02-24 | 2022-10-31 | 다케다 게엠베하 | Uti 융합 단백질 |
| EP3291670A1 (en) * | 2015-05-04 | 2018-03-14 | Laboratoire Français du Fractionnement et des Biotechnologies | Transgenic production of fc fusion proteins |
| WO2016210328A1 (en) | 2015-06-24 | 2016-12-29 | Board Of Regents Of The University Of Texas System | Methods and compositions for treatment of symptoms associated with intracranial hemorrhage |
| DK3355913T3 (da) * | 2015-09-30 | 2024-12-02 | Igm Biosciences Inc | Bindingsmolekyler med modificeret j-kæde |
| JPWO2018079701A1 (ja) * | 2016-10-28 | 2019-09-19 | 株式会社Ｎｒｌファーマ | ラクトフェリン活性を有するタンパク質を含む、抗ガン治療補助剤 |
| WO2018079702A1 (ja) * | 2016-10-28 | 2018-05-03 | 株式会社Ｎｒｌファーマ | ラクトフェリン／アルブミン融合タンパク質及びその製造方法 |
| CR20190372A (es) | 2017-02-17 | 2019-10-17 | Denali Therapeutics Inc | Polipéptidos de unión al receptor de transferrina diseñado |
| CR20200129A (es) | 2017-10-02 | 2020-08-22 | Denali Therapeutics Inc | Proteínas de fusión que comprenden enzimas de terapia de reemplazo de enzimas |
| KR20210024999A (ko) * | 2018-06-26 | 2021-03-08 | 가부시키가이샤 에스 앤드 케이 바이오파마 | 글리코사미노글리칸 저해제 및 촉진제 |
| US20200024329A1 (en) * | 2018-07-17 | 2020-01-23 | Bradley G. Thompson | Methods for regulating endogenous production of lactoferrin and sub-peptides thereof |
| MX2022007486A (es) | 2019-12-23 | 2022-06-29 | Denali Therapeutics Inc | Variantes de progranulina. |
| CN116917336A (zh) * | 2020-11-25 | 2023-10-20 | 阿维鲁斯公司 | 用于治疗病毒感染的方法和组合物 |
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| US5723125A (en) | 1995-12-28 | 1998-03-03 | Tanox Biosystems, Inc. | Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide |
| US6111081A (en) * | 1996-05-31 | 2000-08-29 | Baylor College Of Medicine | Lactoferrin variants and uses thereof |
| JP3681982B2 (ja) * | 1998-07-15 | 2005-08-10 | サムヤン ジェネックス コーポレイション | 酵母からラクトフェリンポリペプチドを大量生産する方法及びそれに有用な微生物菌株 |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| EP1367908B1 (en) | 2001-02-14 | 2014-04-09 | Ventria Bioscience | Expression of human milk proteins in transgenic plants |
| CN1330664C (zh) | 2001-03-07 | 2007-08-08 | 默克专利有限公司 | 用于含杂合同种型抗体部分的蛋白质的表达技术 |
| KR100453877B1 (ko) | 2001-07-26 | 2004-10-20 | 메덱스젠 주식회사 | 연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 ＴＮＦＲ/Ｆｃ 융합 단백질, 상기 단백질을 코딩하는 ＤＮＡ, 상기 ＤＮＡ를 포함하는벡터, 및 상기 벡터에 의한 형질전환체 |
| ES2454666T3 (es) * | 2003-11-13 | 2014-04-11 | Hanmi Science Co., Ltd. | Fragmento Fc de IgG para un vehículo de fármaco y procedimiento para la preparación del mismo |
| AP2007003920A0 (en) * | 2004-08-03 | 2007-02-28 | Biorexis Technology Inc | Combination therapy using transferrin fusion proteins comprising glp-1 |
| JP4261531B2 (ja) * | 2005-09-06 | 2009-04-30 | 株式会社Ｎｒｌファーマ | ラクトフェリン複合体及びその製造方法 |
| UY30820A1 (es) | 2006-12-21 | 2008-07-03 | Centocor Inc | Uso de agonistas del receptor de glp-1 de accion prolongada para mejorar la sensibilidad a la insulina y los perfiles lipidicos |
| KR101380732B1 (ko) | 2007-05-30 | 2014-04-10 | 포항공과대학교 산학협력단 | 면역글로불린 융합 단백질 |
| US8273351B2 (en) | 2008-04-25 | 2012-09-25 | Dyax Corp. | Fc receptor binding proteins |
| JP2010138160A (ja) | 2008-11-14 | 2010-06-24 | Nrl Pharma Inc | 肝機能保護医薬品組成物 |
| JP2010215522A (ja) | 2009-03-13 | 2010-09-30 | Nrl Pharma Inc | 皮膚疾患治療用又は皮膚疾患予防用医薬組成物、及び、皮膚疾患予防用化粧料 |
| KR102177252B1 (ko) | 2012-04-23 | 2020-11-10 | 가부시키가이샤 에스 앤드 케이 바이오파마 | 락토페린 융합 단백질 및 그의 제조방법 |
| JP2015027981A (ja) | 2013-07-05 | 2015-02-12 | 富士フイルム株式会社 | 腸溶性細粒及び医薬組成物 |
| WO2018079702A1 (ja) | 2016-10-28 | 2018-05-03 | 株式会社Ｎｒｌファーマ | ラクトフェリン／アルブミン融合タンパク質及びその製造方法 |
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2013
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2015
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| ES2671631T3 (es) | 2018-06-07 |
| US20150093382A1 (en) | 2015-04-02 |
| BR112014026162A2 (pt) | 2017-10-03 |
| EP2842969A1 (en) | 2015-03-04 |
| JPWO2013162050A1 (ja) | 2015-12-24 |
| EP2842969B1 (en) | 2018-03-14 |
| CN104245739A (zh) | 2014-12-24 |
| US20180072794A1 (en) | 2018-03-15 |
| KR20150008870A (ko) | 2015-01-23 |
| US10562959B2 (en) | 2020-02-18 |
| CA2871468A1 (en) | 2013-10-31 |
| KR102177252B1 (ko) | 2020-11-10 |
| JP5855239B2 (ja) | 2016-02-09 |
| WO2013162050A1 (ja) | 2013-10-31 |
| JP6356115B2 (ja) | 2018-07-11 |
| US9809641B2 (en) | 2017-11-07 |
| EP2842969A4 (en) | 2016-01-13 |
| IN2014DN09815A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2015-07-31 |
| JP2016117717A (ja) | 2016-06-30 |
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